WP2064

Neural Crest Differentiation

WikiPathways

TWIST1, CDH6, HES1, PMP22, ZIC1, HDAC7, CTBP2, LHX2, ITGB1, AXIN1, NFKB1, MYC, CDH2, HDAC8, HDAC5, HDAC6, HDAC4, COL11A2, ASCL1, NOTCH2, NOTCH1, SNAI2, HDAC3, HOXA1, RHOB, FGF2, TCF4, SOX9, DLL4, FGFR2, ID1, FGFR1, ETS1, FGF19, SMAD1, GSK3B, DLX5, CTNNB1, TCF7L1, HDAC9, BMP4, MITF, HDAC1, HDAC2

WP2112

IL17 signaling pathway

WikiPathways

STAT3, RELA, GSK3B, CEBPB, TRAF3IP2, IL17RB, CEBPD, MAP3K7, JAK1, AKT1, JAK2, MAPK3, NFKB1, MAPK1

WP2113

Type III interferon signaling

WikiPathways

STAT2, IRF9, JAK1, IL10RB

WP2118

Arrhythmogenic Right Ventricular Cardiomyopathy

WikiPathways

CACNA2D1, CACNB3, ITGA9, RYR2, CACNG8, JUP, CACNG6, LMNA, ATP2A2, ITGA3, ITGA5, EMD, ACTN4, DSC2, ITGA11, DSG2, ACTN1, DMD, CACNA1C, ITGB3, ITGB4, ITGB5, ITGAV, ITGB1, ACTG1, PKP2, CTNNA1, CDH2, TCF7L2, SGCD, ITGA10, SGCB, CTNNA2, DAG1, CTNNB1, LAMA2, GJA1, ITGB8, ACTB, ITGA6, ITGA2, TCF7L1, DSP, DES, ACTN2

WP2190

One carbon donor

WikiPathways

MTHFR

WP2197

Endothelin Pathways

WikiPathways

CALM2, PLCB1, RAMP1, RAF1, ECE1, PRKCA, ATP2A2, GNAI1, ADRB1, MYLK, NOS3, CNN1, ADRA1A, MAP2K1, GNAS, NPY1R, EDN1, CAD, EDNRA, MAPK1

WP22

IL-9 Signaling Pathway

WikiPathways

IL9R, MAP2K2, STAT3, MAP2K1, JAK1, JAK3, GRB2, STAT5B, MAPK3, STAT5A, PIK3R1, MAPK1

WP2249

Metastatic brain tumor

WikiPathways

TP53, CDK6, PIK3R1, CDC42, MYC

WP2253

Pilocytic astrocytoma

WikiPathways

PTPN11, GRB2, SOS1

WP2261

Signaling Pathways in Glioblastoma

WikiPathways

E2F1, FOXO4, PRKCB, RAF1, PRKCA, TSC2, IGF1R, MSH6, PRKCI, PRKCD, PDGFRB, ERBB2, BRCA2, ERBB3, MAP2K2, MDM4, PRKCQ, BRCA1, MAP2K1, MAP2K7, FGFR2, MDM2, MAP2K5, MAP2K6, RB1, AKT1, AKT2, FGFR1, AKT3, NRAS, GRB2, MAPK3, MAPK1, MIR21, EP300, EGFR, KRAS, CDKN1B, CDKN1A, CDKN2B, CDKN2C, PIK3C2A, MET, PTEN, SPRY2, FOXO1, PDGFRA, FOXO3, CDK2, CDK4, TP53, PIK3CA, PIK3CB, CDK6, ERRFI1, PIK3CD, GAB1, PLCG2, IRS1, CCND2, PIK3CG, PIK3R1

WP2267

Synaptic Vesicle Pathway

WikiPathways

STX2, SNAP25, SLC1A3, ATP1A2, AP2A2, AP2B1, CPLX2, VAMP2, STX3, SLC22A3, AP2S1, NSF, AP2M1, STXBP1, SYN1, SLC38A1, SYN2, SYT1, SLC25A4, CLTA, SLC18A2

WP2272

Pathogenic Escherichia coli infection

WikiPathways

TUBA1A, PRKCA, KRT18, CLDN1, TUBB4A, TUBB4B, TUBB3, RHOA, CTTN, TUBB2A, WASL, OCLN, TUBA1B, ARPC4, CD14, ITGB1, ARPC3, ACTG1, ARPC2, TUBA3C, TLR5, TUBB2B, CTNNB1, TUBA4A, ACTB, ROCK2, TUBB1, HCLS1, EZR, ARHGEF2, TLR4, TUBB6, YWHAZ, TUBB, FYN, CDC42

WP2276

Glial Cell Differentiation

WikiPathways

TPPP, MAG, GAP43, PLP1, CNP

WP2289

Drug Induction of Bile Acid Pathway

WikiPathways

ABCC4, SULT2A1, CYP3A4, SLC51A, VDR, NR1H4

WP229

Irinotecan Pathway

WikiPathways

NPC1, ABCC1, APC, CYP3A5, CYP3A4

WP2290

RalA downstream regulated genes

WikiPathways

RAC2, EXOC2, NRAS, RALA, RAC3, KRAS, RALBP1, RAC1, CDC42

WP2291

Deregulation of Rab and Rab Effector Genes in Bladder Cancer

WikiPathways

RAB27A, RPH3AL, SYTL4, MYRIP, SYTL5, MLPH, SYTL2, RAB27B, EXPH5

WP23

B Cell Receptor Signaling Pathway

WikiPathways

MEF2C, JUN, MEF2D, ELK1, BCL6, VAV1, MAP3K7, CREB1, AKT1, PIP5K1B, NFKB1, MYC, MAPK14, RELA, PIP5K1C, REL, BLNK, FOXO1, CRKL, PLCG2, NFATC2, GTF2I, CDC42, PTPN11, RAF1, PRKCB, PRKCD, INPP5D, MAPK9, RAC2, MAP2K2, MAP2K1, MAP2K6, CD81, RAPGEF1, GRB2, ETS1, RAC1, PTPRC, SOS1, RPS6KA1, MAPK1, MAPK8, ILF2, GSK3B, SYK, HCLS1, GAB1, BCL10, FYN, PIK3CG, PIK3R1, LYN

WP231

TNF alpha Signaling Pathway

WikiPathways

JUN, CASP9, CASP8, TAB3, RAF1, TXN, TNF, CCL2, BIRC3, FADD, CFLAR, CREBBP, RIPK1, BAD, OTUD7B, MAPK9, MAP3K5, BID, PSMD2, BAX, CDC37, MAP2K7, MAP3K8, MAP2K6, MAP3K7, TNFRSF1B, AKT1, NRAS, GRB2, RFFL, TNFAIP3, MAPK3, NFKB1, RAC1, SOS1, MAPK1, NSMAF, MAPK8, RFK, SELE, KRAS, BTRC, SKP1, TANK, HSP90AA1, PLK1, TRAF1, TRADD, REL, TBK1, TAB1, IL6

WP2324

AGE/RAGE pathway

WikiPathways

JUN, CASP9, CASP8, FOXO4, STAT3, RAF1, PRKCB, PRKCA, INHBB, RHOA, INS, ALPL, PRKCD, MAPK9, MMP2, NOS3, MMP9, PLA2G4A, MAP2K1, HIF1A, AKT1, JAK2, DDOST, SMAD3, MAPK3, STAT5B, STAT5A, INSR, NFKB1, LGALS3, RAC1, MAPK1, SMAD2, MAPK8, TIRAP, MAPK14, EGFR, RELA, MMP14, FOXO1, EZR, CYCS, IRS1, CDC42

WP2328

Allograft Rejection

WikiPathways

CASP9, CASP8, HLA-DOB, CD28, TNF, MICA, HLA-C, COL5A1, HLA-B, HLA-DMB, HLA-DMA, HLA-A, CXCL8, FOXP3, HLA-G, IL12A, IL1A, TUBA1B, IL10, HLA-DRB5, HARS, TGFB1, VEGFA, IL1B, C4A, HLA-F, HLA-E, HLA-DPA1, CD40LG, GABPA, HLA-DQA1, HLA-DQA2, PDGFRA, HLA-DQB1, VIM, CXCL12, FAS, C3, AGTR1, HLA-DRB1, HLA-DRA

WP2332

Interleukin-11 Signaling Pathway

WikiPathways

RUNX2, STAT3, PTPN11, RAF1, RELA, BIRC5, ICAM1, TGFB1, SOCS3, ITGA2, BCL2, MAP2K2, IL6ST, MAP2K1, BGLAP, CREB1, JAK1, AKT1, JAK2, PPP2R4, ATF1, GRB2, MAPK3, FYN, PIK3R1, RPS6, IL11, RPS6KA1, MAPK1

WP2333

Trans-sulfuration pathway

WikiPathways

CSAD, MAT2B, MTR, GCLM, CBS, MPST, CTH, AHCY, DNMT1

WP2338

miRNA Biogenesis

WikiPathways

DICER1

WP2355

Corticotropin-releasing hormone signaling pathway

WikiPathways

STAR, CASP9, RAF1, PRKCB, ELK1, PRKCA, HSD3B2, HSD3B1, ADRBK2, JUP, SULT2A1, JUND, JUNB, CYP11A1, RHOA, NR4A2, PRKCI, TRIM28, POMC, PRKCD, CXCL8, TCF4, MAP3K5, MAPK9, PTK2, NOS3, PRKCQ, MAP2K1, CYP21A2, CREB1, AKT1, FOSL1, CYP11B1, MAPK3, NFKB1, MAPK1, MAPK8, MAPK14, ECE1, FOSL2, KRT1, IL18, FOSB, RELA, GSK3B, GNA11, GNB3, GNB2, CTNNB1, GJA1, GNAI1, GNAI2, TGFB1, HSP90AA1, PRKAA2, BCL2, ERN1, GNAQ, GNAS, GRK6, NCOA2, GNB1, NR4A1, PLCG2, TLR4, FOS, PARP1

WP2359

Parkin-Ubiquitin Proteasomal System pathway

WikiPathways

CASP8, TUBA1A, CASK, TUBB4A, TUBB4B, TUBB3, RNF19A, HSPA1L, HSPA1B, TUBB2A, PSMD2, PSMD3, HSPA1A, PSMC6, PSMC4, PSMC3, HSPA5, PSMC1, PARK2, CASP1, HSPA4, PSMC2, TUBA1B, HSPA6, TUBA3C, PSMD11, PSMD12, TUBB2B, SNCAIP, STUB1, PSMD7, UBE2J2, PSMD10, TUBA4A, SIAH2, SIAH1, TUBB1, SNCA, UBA1, HSPA14, GPR37, TUBB6, TUBB

WP236

Adipogenesis

WikiPathways

MEF2C, TWIST1, MEF2D, STAT3, MEF2A, PPARGC1A, STAT2, KLF6, CISD1, IGF1, GADD45B, NAMPT, PTGIS, UCP1, TRIB3, RORA, HIF1A, CREB1, CYP26A1, STAT5B, STAT5A, RBL1, LPL, PRLR, SOCS1, GATA4, KLF15, TGFB1, NCOA1, GTF3A, GADD45A, PLIN1, DDIT3, ID3, SOCS3, WNT5B, FOXO1, ADIPOQ, IRS2, SERPINE1, NCOA2, AGT, E2F1, NR2F1, BMP1, TNF, AHR, SLC2A4, LPIN1, LMNA, CEBPB, HNF1A, SCD, CEBPD, INS, NR1H3, MBNL1, NCOR2, NCOR1, PLIN2, NR3C1, RB1, DLK1, LEP, SMAD3, CYP26B1, EGR2, PCK2, PCK1, EPAS1, LIPE, CDKN1A, NRIP1, CTNNB1, PPARA, IL6ST, KLF7, BMP3, BMP4, HMGA1, BMP2, PNPLA3, PPARG, PPARD, MIF, RETN, FAS, GH1, LIF, LIFR, IRS1, SREBF1, IRS4, SFRP4, IL6

WP2361

Gastric Cancer Network 1

WikiPathways

SMOC2, S100P, NOTCH1, TPX2, AURKA, CCNA1, RNF216, ACTL6A, MCM4, ECT2, CEP192, KIF15, UBE2C, INO80D, APC, RUVBL1, TOP2A, CENPF, NUP107, MYBL2, KIF20B, H3F3A, ESM1

WP2363

Gastric Cancer Network 2

WikiPathways

FANCI, COL9A1, EGFR, CHTF18, ATAD2, CD48, CTNNB1, MTDH, AHCTF1, RFC4, UBE2T, LMNB2, CEBPZ, UBE2C, S100A6, RFC3, TOP2A, DSCC1, TP53, CHTF8, CACYBP, MYC, RNF144B

WP2366

Butyrate-induced histone acetylation

WikiPathways

AKT1

WP2369

Histone Modifications

WikiPathways

EZH2, EZH1, KMT2E, EHMT2, HIST1H4A, SET, SETD6, KMT5C, KMT2C, HIST1H3D, SETDB2, SUV39H2, PRDM2, SMYD3, SETD9, KMT5A, KMT5B, ASH1L, KMT2B, SETD7, SETD5, H3F3A

WP237

Glucocorticoid & Mineralcorticoid Metabolism

WikiPathways

CYP11A1, HSD11B2, HSD11B1, HSD3B2, CYP21A2, HSD3B1, CYP17A1, CYP11B2

WP2371

Parkinsons Disease Pathway

WikiPathways

CASP9, SYT11, PINK1, MAPK13, CASP6, PARK2, UCHL1, EPRS, MAPK14, SNCAIP, UBE2J2, SNCA, UBA7, UBA1, CYCS, CCNE2, GPR37, MIR132, TH

WP2374

Oncostatin M Signaling Pathway

WikiPathways

STAT3, PTPN11, PRKCB, RAF1, PRKCA, CCL2, JUND, JUNB, CEBPB, RICTOR, PRKCD, MAPK9, MMP1, MAP2K2, MAP2K1, HIF1A, CREB1, JAK1, AKT1, JAK3, JAK2, CYR61, GRB2, MAPK3, STAT5B, TIMP3, NFKB1, SOS1, RPS6, MAPK1, MAPK8, EGR1, MAPK14, RELA, KRAS, CDKN1B, LDLR, VEGFA, SOCS3, IL6ST, CDK2, SERPINE1, TP53, OSMR, LIFR, IRS1, FOS, PIK3R1

WP2380

Brain-Derived Neurotrophic Factor (BDNF) signaling pathway

WikiPathways

MEF2C, JUN, FRS2, STAT3, MEF2A, ELK1, ADAM17, EIF4E, SQSTM1, EIF4EBP1, RPS6KA5, NCF2, CREB1, AKT1, JAK2, SPP1, ACACB, TIAM1, SH2B1, STAT5B, STAT5A, CAMK1, NFKB1, CDH2, NFATC4, MAPK14, RELA, CFL1, CYFIP1, NGF, PRKAA2, BDNF, NGFR, BCL2L11, CNR1, SIRPA, FOXO3, APC, IRS2, CDC42, PTPN11, RAF1, EEF2, TSC2, RACK1, DOK5, BAD, ALPL, PRKCD, MAPK9, MAP2K2, PTPRF, MAP2K1, MAP2K5, MARCKS, GRB2, MAPK3, KIDINS220, MAPK7, RAC1, RPS6, RPS6KA1, MAPK1, RANBP9, EGR2, MAPK8, EGR1, NCAM1, GSK3B, CTNNB1, DPYSL2, NSF, YBX1, RAP1A, MAPT, SYN1, EIF2S1, BMP2, DLG1, CDK5, SHC2, IRS1, FYN, FOS, NTRK2, NTRK1, VAV3, PIK3R1

WP24

Peptide GPCRs

WikiPathways

OXTR, CXCR4, CXCR2, CCKBR, MC2R, NPY6R, NPY5R, NPY1R, NPY2R, EDNRA, MC4R, SSTR1, FPR2, FPR1, C5AR1, OPRL1, AVPR2, GNRHR, GHSR, LHCGR, FSHR, AGTR1, AGTR2, SSTR5

WP2406

Cardiac Progenitor Differentiation

WikiPathways

MEF2C, NRG1, NOTCH1, BMP1, IGF1, INHBA, IGF2, FGF2, CXCR4, INS, TNNI3, KIT, DKK1, ACTC1, SOX17, NCAM1, MAPK14, GSK3B, GATA4, LIN28A, TGFB1, POU5F1, SIRPA, PDGFRA, BMP4

WP241

One Carbon Metabolism

WikiPathways

MTHFD2, TYMS, DNMT1, AHCY, GLRX, DNMT3B, MTHFS, SHMT1, MTHFD1L, GART, ALDH1L1, MTFMT, DHFR, MAT2B, MTHFD1, MTR, MTHFR

WP2431

Spinal Cord Injury

WikiPathways

ZFP36, TNFSF13, CCL2, PRB1, MMP9, PTGS2, SLIT2, PLXNA2, IL1A, FCGR2A, MYC, SEMA6A, TNFSF13B, ACAN, TGFB1, GADD45A, GAP43, MAG, BDNF, NGFR, VCAN, RTN4, FOXO3, CSPG4, NCAN, VIM, CDC42, E2F1, CXCL1, PRKCA, TNF, CDK1, ICAM1, RHOB, RHOA, CXCL8, SOX9, BTG2, PLA2G2A, EFNB2, ANXA1, PLA2G5, RB1, LEP, MAPK3, LGALS3, RAC1, MAPK1, EGR1, EGFR, CDKN1B, CD47, GJA1, IL1B, IL1R1, BCAN, ROCK2, EPHA4, CDK2, CXCL2, CDK4, CHST11, TP53, PPP3CA, MIF, NR4A1, NOX4, TLR4, FOS, CCNG1, IL6

WP2435

Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis

WikiPathways

JUN, MMP1, PTGS2, ACOX2, CYP2A6, MAFG, VEGFA, NFKB1, FOS

WP2436

Dopamine metabolism

WikiPathways

MAOB, MAOA, PRKACA, TYR, COMT, NQO1, PPP2CB, TH

WP244

Alpha 6 Beta 4 signaling pathway

WikiPathways

PTPN11, MAPK14, PRKCA, LAMA3, LAMA2, RHOA, EIF4EBP1, ITGA6, PRKCD, PTK2, IRS2, ITGB4, AKT1, GAB1, GRB2, LAMC1, IRS1, MAPK3, LAMB1, RAC1, PIK3R1, SOS1, MAPK1

WP2446

Retinoblastoma (RB) in Cancer

WikiPathways

SMARCA2, E2F1, HMGB2, RAF1, HMGB1, TFDP1, FANCG, CDC7, TYMS, KIF4A, CDK1, RFC4, STMN1, RFC5, RBP1, MSH6, POLD3, RPA3, CDT1, BARD1, RBBP4, MAPK13, MDM2, RFC3, RB1, SKP2, DHFR, PRKDC, MYC, SMC1A, MIR21, CCDC6, RRM1, PRIM1, RRM2, CDKN1B, CDKN1A, DNMT1, SMC3, POLA1, ZNF655, TTK, PCNA, PLK4, POLE2, NPAT, MCM4, MCM3, MCM6, CCNA2, MCM7, SMC2, POLE, CDK2, CHEK1, CDK4, WEE1, TOP2A, H2AFZ, ANLN, TP53, E2F2, ORC1, CDK6, CDC25B, CCNE2, CCNB2, CDC25A, HDAC1, DCK, CCNB1, FAF1, CCND3

WP2447

Amyotrophic lateral sclerosis (ALS)

WikiPathways

CASP9, MAPK14, TNF, ALS2, GPX1, BAD, RAB5A, CCS, MAP3K5, BCL2, BID, MAP2K2, BAX, SLC1A2, NEFH, MAP2K6, CASP1, TP53, PPP3CA, CST3, RAC1, TOMM40

WP2453

TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)

WikiPathways

DLST, PCK1, PDHA1, DLD, DLAT, MDH1, PC, FH, SDHA, OGDH, IDH1

WP247

Small Ligand GPCRs

WikiPathways

PTGFR, PTGDR, PTGER2, PTGER4, PTGER3, S1PR1, S1PR3, PTAFR, MTNR1A, MTNR1B, CNR1

WP2485

NAD Biosynthesis II (from tryptophan)

WikiPathways

KYNU, KMO, QPRT, NADSYN1

WP2491

Diclofenac Metabolic Pathway

WikiPathways

CYP2B6

WP2507

Nanomaterial induced apoptosis

WikiPathways

CASP9, CASP8, BID, BAX, CASP6, MCL1, CYCS, FAS, FADD, CFLAR, AIFM1

WP2509

Nanoparticle triggered autophagic cell death

WikiPathways

MAP1LC3A, CHAF1A, BCL2, ULK1, VMP1, ATG10, SH3GLB1, TSC2, ATG12, INSR, INS

WP2513

Nanoparticle triggered regulated necrosis

WikiPathways

CASP8, MAPK8, FADD, PLA2G4A, RIPK1, FTL, TRADD, PARP1

WP2516

ATM Signaling Pathway

WikiPathways

JUN, SMC1A, NBN, CDKN1A, CDK1, CRADD, GADD45A, RIPK1, RAD51, RAD50, FANCD2, MDC1, MAPK9, MRE11A, BID, MDM4, BRCA1, RAD9A, CDK2, CHEK1, MDM2, CREB1, H2AFX, TP53, TLK1, CDC25C, CDC25A, CCNB1

WP2525

Trans-sulfuration and one carbon metabolism

WikiPathways

MTHFD2, TYMS, GCLC, AHCY, DNMT1, DNMT3B, MTHFD2L, SHMT1, MTHFD1L, PHGDH, PSAT1, GCLM, AHCYL1, DHFR, MAT2B, MTHFD1, MTR, MTHFR, CBS, CTH, MAT2A

WP2526

PDGF Pathway

WikiPathways

JUN, MAPK8, PTPN11, STAT3, RAF1, ELK1, RHOA, PDGFRB, PDGFA, WASL, PDGFB, PLA2G4A, MAP2K1, VAV1, JAK1, RASA1, GRB2, TIAM1, MAPK3, FOS, RAC1, PIK3R1, CDC42, SOS1, MAPK1

WP2533

Glycerophospholipid Biosynthetic Pathway

WikiPathways

AGPS, PLA2G2A, GK, PEMT, PTPMT1, CDS2, LPIN1, PCYT2, PTDSS1, CEPT1, CHKB, GNPAT, CRLS1, PGS1

WP2536

Colchicine Metabolic Pathway

WikiPathways

CYP3A4

WP254

Apoptosis

WikiPathways

JUN, CASP9, CASP8, BIRC5, TNF, TNFSF10, IGF1, BIRC3, XIAP, CRADD, IGF1R, IGF2, FADD, CFLAR, RIPK1, BAD, BID, BAX, CASP4, MDM2, CASP6, CASP1, TNFRSF1B, AKT1, PMAIP1, NFKB1, MYC, RELA, BNIP3L, BOK, HELLS, BBC3, IRF1, SCAF11, BCL2L11, TRAF1, TRADD, TNFRSF25, BCL2, BCL2L2, TP53, MCL1, TNFRSF21, FAS, DFFA, CYCS, PIK3R1, IRF6

WP2542

Sulindac Metabolic Pathway

WikiPathways

MSRB3, CYP1B1

WP2572

Primary Focal Segmental Glomerulosclerosis FSGS

WikiPathways

LRP5, LRP6, NOTCH1, PARVA, WT1, CLDN1, VTN, ITGA3, FAT1, ACTN4, PLAUR, MME, CD151, PTK2, COL4A3, DKK1, ITGB3, ILK, ITGB4, AKT1, KRT8, CTSL, ITGAV, ITGB1, CR1, MYO1E, CDH2, CDKN1C, CDKN1B, DAG1, CDKN1A, CTNNB1, TGFB1, LIMS1, PTPRO, PCNA, VIM, JAG1, TLR4, MKI67, MYH9, TLN1, TRPC6, FYN, IRF6

WP2583

T-Cell Receptor and Co-stimulatory Signaling

WikiPathways

CALM2, CSNK1A1, PRKCA, CD28, PDK1, GSK3B, DYRK2, PTEN, AKT1, RASA1, PPP3CA, FYN, NFATC2, NFKB1

WP2586

Aryl Hydrocarbon Receptor

WikiPathways

LPL, E2F1, RAF1, EP300, EGFR, RELA, KLF6, TNF, KRAS, GCLC, ESR1, CDKN1B, AHR, CDKN1A, NRIP1, CD36, NQO1, VEGFA, AIP, HSP90AA1, PLAGL1, CYP1A1, CYP1B1, PSRC1, AHRR, NCOR2, PTGS2, CDC37, MAP2K1, CDK2, NCOA7, RB1, NRAS, ARNT, NFKB1, MYC, MAPK1

WP2596

Gastric acid production

WikiPathways

CCK, SCT

WP2597

Secretion of Hydrochloric Acid in Parietal Cells

WikiPathways

CCKBR

WP26

Signal Transduction of S1P Receptor

WikiPathways

PLCB1, RACGAP1, GNAI1, GNAI2, SPHK1, S1PR1, S1PR3, GNAI3, AKT1, AKT2, ASAH1, AKT3, MAPK3, MAPK7, MAPK1

WP262

EBV LMP1 signaling

WikiPathways

MAPK8, RELA, TNF, MAP3K7, PDLIM7, CCL5, CCL20, HSP90AA1, NFKB1, IRAK1, TRAF1, TRADD, CXCL8, MAPK1

WP2636

Common Pathways Underlying Drug Addiction

WikiPathways

CALM2, RAF1, PRKCB, PRKCA, GNAI1, GRIA4, ACTB, RAP1A, GRIN2A, MAP2K2, MAP2K1, PRKACA, CREB1, GNAS, PPP1R1A, PPP1CC, PPP1CB, PPP1CA, MAPK3, DRD2, ACTG1, ACTG2, MAPK1

WP2637

Structural Pathway of Interleukin 1 (IL-1)

WikiPathways

TAB3, ELK1, MKNK1, EIF4E, MAPK9, MAP2K2, RPS6KA5, MAP2K1, MAP2K7, MAP3K8, MAP3K7, IL1A, MAP2K6, MAPK3, NFKB1, MYC, MAPK1, MAPK8, MAPK14, RELA, MAPKAPK2, MKNK2, TOLLIP, TANK, IL1RAP, IRAK2, IL1R1, IRAK1, TAB1, FOS

WP2643

Nanoparticle-mediated activation of receptor signaling

WikiPathways

MAPK8, RAF1, MAPK14, EGFR, KRAS, FN1, MAPK9, PTK2, MAP2K2, MAPK13, MAP2K1, ITGB1, AKT3, PIK3CD, NRAS, GRB2, AREG, COL1A1, TLN1, SOS1, MAPK1

WP2646

Lidocaine metabolism

WikiPathways

CYP3A4

WP268

Notch Signaling Pathway

WikiPathways

NOTCH2, HES1, NOTCH1, NUMB, PSEN2, PSEN1, PTCRA, APH1A, ADAM17, RFNG, APH1B, CREBBP, CTBP2, NCOR2, DLL4, KAT2B, JAG1, MAML3, INPP5K, HDAC1, HDAC2

WP272

Blood Clotting Cascade

WikiPathways

F8, F2, VWF, FGG, FGA, SERPINE1, PLG, FGB, PLAT, F13B, F5, PLAU

WP2795

Cardiac Hypertrophic Response

WikiPathways

CALM2, RAF1, MEF2A, PRKCA, NRG1, TNF, IGF1, FGF2, PRKD1, HDAC7, MAP2K2, PLA2G2A, MAP2K1, FGFR2, MAP2K7, MAP2K5, MAP3K7, MAP2K6, AKT1, AKT2, MAPK3, MAPK7, NFKB1, RAC1, MAPK1, MAPK8, MAPK14, GSK3B, HDAC5, TGFB1, TGFBR1, CAMK2D, HDAC9, HDAC4, PPP3CA, CDK7, NFATC2

WP28

Selenium Metabolism and Selenoproteins

WikiPathways

JUN, SELT, SARS, RELA, TXNRD1, CREM, TRNAU1AP, SEPN1, SEPHS1, SEPP1, GPX1, SECISBP2, GPX3, GPX4, SELM, SELENBP1, EPT1, DIO2, SELENOH, RPL30, SEPSECS, SCLY, VIMP, SP3, CTH, POU2F1, FOS, NFKB1

WP2805

RNA interference

WikiPathways

DICER1

WP2816

Felbamate Metabolism

WikiPathways

CYP2E1, CYP3A4

WP2828

Bladder Cancer

WikiPathways

E2F1, EGFR, CDKN1A, TYMP, VEGFA, CXCL8, ERBB2, MMP1, MAP2K2, RPS6KA5, MAP2K1, CDK4, MDM2, RB1, RASSF1, TP53, DAPK3, PIK3R1, DAPK1, THBS1, MYC, MAPK1

WP2846

Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation

WikiPathways

LDLR, PCSK9

WP2848

Differentiation Pathway

WikiPathways

CSF1R, NOTCH1, HGF, GDF5, IGF1, WNT2, WNT5A, INHBA, TGFB1, KITLG, VEGFA, FGF2, TF, FST, INS, NT5E, TNFSF11, IL6R, PDGFA, PDGFB, DKK1, KIT, BMP4, WNT2B, IL6, IL11

WP2849

Hematopoietic Stem Cell Differentiation

WikiPathways

RUNX1, IKZF1, NOTCH1, KITLG, KCNH2, GYPA, CXCR4, IL1B, ACVR1B, VAV1, ITGB3, IL1A, MXI1, STAT5A, NFATC2, FOS, RIOK3, LMO2, IL6

WP2853

Endoderm Differentiation

WikiPathways

EZH2, HHEX, SFRP1, CEBPZ, BTAF1, CTBP2, ZNF462, PTHLH, NCAPG2, UBR5, TOX3, NME1, LAMC1, TAF5, SOX17, GATA6, GATA4, DNMT3B, DUSP2, TGFB1, ELAVL1, TNRC6C, RGS10, SIAH2, DUSP5, CDYL, NLK, FOXO1, APC, FOXN3, TOX, LRPPRC, WWC1, DIP2A, NABP2, NAA15, NOTCH1, ZBTB17, ELP4, HOXA1, C1QBP, TCF4, NR3C1, DKK1, BCORL1, RTF1, CUL4B, SMAD3, SMAD4, SMAD2, DAB2, EXT1, ASCC3, PARP8, PBX1, EMSY, WNT3, DDAH1, CTNNB1, OTX2, POU5F1, NKX2-1, CAND1, MTF2, BMPR1A, TCF7L1, SESN1, GLI2, APP, WDHD1, VAV3

WP2854

Gene regulatory network modelling somitogenesis

WikiPathways

HES1, NOTCH1, EPHA4

WP2855

Dopaminergic Neurogenesis

WikiPathways

STAT3, ALDH1A1, CDKN1C, TGFB1, OTX2, NR4A2, GLI2, ASCL1, SLC18A2, TH

WP2857

Mesodermal Commitment Pathway

WikiPathways

RPL38, FOXC1, FZD4, FZD8, MEIS1, TRIM28, CTBP2, ZNF462, NCAPG2, UBR5, KDM6A, JAK2, ADAM19, TOX3, AXIN1, SOX17, CCDC6, BHLHE40, GATA6, DNMT3B, RGS10, SMAD6, YAP1, CSRP2, NLK, ACVR2B, ACVR2A, ACVR1, PRKACA, MACF1, TOX, TBX1, PRKAR1A, DIP2A, NABP2, ELP4, INHBA, TEAD2, C1QBP, TCF4, DKK1, BCORL1, FGFR1, LATS1, CUL4B, SMAD3, KLF4, SMAD4, CCDC88A, SMAD1, SMAD2, EXT2, EXT1, ASCC3, PARP8, PBX1, EMSY, C9orf72, HMGA2, WNT3, DDAH1, ARID5B, POU5F1, PITX2, AMH, MTF2, BMPR2, BMPR1A, TCF7L1, BMP4, SESN1, WDHD1, VAV3, HTT

WP2858

Ectoderm Differentiation

WikiPathways

CDH6, RHPN1, HMGB2, NLGN1, CCL2, JUP, FZD4, FZD8, SKIL, STC1, ELOVL4, PLXNA2, AES, WDR44, TOX3, UBTF, RIT1, RAB8B, MYC, TRIM33, GATA6, HDAC6, NLK, PDE7A, CCDC130, PLCXD3, SDCBP, PGM1, NF2, NFATC1, TSC22D1, AHI1, LDB2, MZF1, ZBTB16, NR2F2, SOCS2, TCF3, ST8SIA4, DMD, FGFR2, TNFRSF11B, GREB1, SMAD4, PTPRB, TTC14, CTNNA2, CTNNB1, RRBP1, BAZ1A, TBL1X, HIST1H2BH, ABCC4, BMPR1A, SNCA, SPRY2, MAFB, TCF7L1, BMP4, GLI3, PPARD, MKS1, OGT, LY6E, FYN, GRAMD1B

WP286

IL-3 Signaling Pathway

WikiPathways

JUN, ENPP3, STAT3, PTPN11, RAF1, BAD, INPP5D, CXCL8, MAP2K1, VAV1, JAK1, AKT1, JAK2, RAPGEF1, GRB2, STAT5B, MAPK3, STAT5A, SOS1, MAPK1, MAPK8, TGFB1, SYK, YWHAB, BCL2, PRKACA, CRKL, PIK3CD, FYN, FOS, IL5RA, LYN, PIK3R1

WP2864

Apoptosis-related network due to altered Notch3 in ovarian cancer

WikiPathways

F2R, NRG1, TNF, RIPK2, BIRC5, PAK2, JUND, NQO1, SQSTM1, PKN1, IL7R, BCL3, PTK2, ERBB3, IER3, CUL5, ANXA5, HSPA5, AKT1, APOE, AXIN1, ETS1, NFKB1, CTNNA1, MAPK1, GCLC, CDKN1B, CDKN1A, HSPB1, HELLS, NET1, SOCS3, TRAF1, SMAD7, ERN1, SERBP1, HSPD1, TNFRSF21, APP, VIM, HDAC1, VAV3, THBS1

WP2865

IL1 and megakaryocytes in obesity

WikiPathways

F2, F2R, MMP9, IL18, CCL2, S100A9, PLA2G7, ICAM1, PIK3CA, TIMP2, HBEGF, TIMP1, IL1B, SELENBP1, TLR1, NFKB1, TLR2, IL1R1, IRAK1

WP2868

TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer

WikiPathways

STAT3, EGFR, MAPK3, JAK1, MAPK1

WP2870

Extracellular vesicle-mediated signaling in recipient cells

WikiPathways

TSPAN8, RAF1, EGFR, HGF, KRAS, WNT5A, CTNNB1, TGFB2, TGFB1, TGFBR3, TGFBR2, TGFBR1, MET, ERBB2, TGFA, APC, AKT1, NRAS, AXIN1, SMAD3, SMAD4, MFGE8, SMAD2

WP2873

Aryl Hydrocarbon Receptor Pathway

WikiPathways

JUN, HES1, EGFR, EP300, TNF, CDKN1B, AHR, JUND, JUNB, NQO1, NCOA1, TGFB1, AIP, IGFBP1, HSP90AA1, IL1B, CYP1A1, SLC7A5, CYP1B1, POLK, AHRR, IL12A, BAX, CDC37, CES3, MGST1, ARNT, PTGES3

WP2874

Liver X Receptor Pathway

WikiPathways

SCD, FASN, SREBF1, CYP2B6, ABCG8, NR1H3, CYP3A4

WP2875

Constitutive Androstane Receptor Pathway

WikiPathways

SMC1A, PPARGC1A, CYP3A5, SULT2A1, CYP3A4, CYP2A6, NCOA1, HSP90AA1, FOXO1, NCOA2, PPP2R4, DNAJC7, CYP2C9, CYP2B6

WP2878

PPAR Alpha Pathway

WikiPathways

CPT1A, SCP2, APOA2, APOA1, CDK1, PPARA, SLC27A1, CYP8B1, DBI, NR1H3, APOA5, CDK4, APOC3, MYC

WP2879

Farnesoid X Receptor Pathway

WikiPathways

PPARGC1A, IRS2, FKBP5, CYP3A4, SULT2A1, CYP8B1, NR0B2, SLCO2B1, NR1H4, UGT2B4, FGF19

WP288

NLR Proteins

WikiPathways

MAPK8, RELA, MAP3K7, EPHB2

WP2881

Estrogen Receptor Pathway

WikiPathways

PPARA, JUN, PDK4, STAT3, PCK1, NR0B2, ACOX1, CYP1A1, ESR1, GPAM, CYP1B1

WP2884

NRF2 pathway

WikiPathways

TXN, NRG1, SLC39A8, HGF, SLC39A14, TXNRD1, DNAJB1, SLC7A11, NQO1, GSTP1, GSTT2, SQSTM1, PGD, GSTM1, GSTA4, GSTM4, GSTM3, GSTM2, CBR1, SLC2A10, TGFB2, MAFG, TGFB1, HSP90AA1, TGFBR2, SLC39A6, PDGFB, CES3, HSP90AB1, PRDX1, SLC2A14, HBEGF, SLC6A14, SLC2A5, BLVRB, SLC2A4, SLC2A3, SLC2A1, SERPINA1, ABCC5, SLC5A11, SOD3, TGFA, HSPA1A, SLC2A6, MGST2, PTGR1, MGST3, PRDX6, FGF13, FTL, GSTA1, GSR, EGR1, GCLC, SLC6A8, CYP2A6, GPX3, ADH7, ABCC4, EPHA3, GCLM, SLC5A3, SLC5A5, PPARD, SLC6A1, MAFF, HMOX1, SLC39A4, G6PD, SLC6A6, FTH1, SLC39A10

WP2889

Oxytocin signaling

WikiPathways

PLCD1, OXTR, GNAQ

WP289

Myometrial Relaxation and Contraction Pathways

WikiPathways

JUN, CALM2, CALD1, OXTR, ATP2A2, IGFBP1, IGFBP2, IGFBP3, DGKZ, PKIG, ITPR3, GSTO1, RGS5, IGFBP6, IGFBP5, IGFBP4, CREB1, FLJ10038, NFKB1, PDE4D, GNG7, GNG5, GNB3, GNB2, GNG4, GNG11, ADCY3, MYL4, RGS7, RGS10, YWHAB, CNN1, CAMK2D, PRKACA, GNAQ, GNAS, PKIA, CRCP, GNB1, PRKAR1A, PLCG2, PRKAR2A, YWHAZ, CALM3, YWHAH, YWHAE, ADCY9, CACNB3, SFN, PLCD1, ADCY7, PRKCB, PRKCA, PRKAR2B, RYR2, RYR3, PRKD1, PRKCD, NOS3, PRKCQ, ACTC1, ACTG1, ETS2, RAMP3, RAMP1, ACTA2, ADM, ITPR1, ITPR2, GJA1, IL1B, ACTB, GABPA, GRK6, RGS2, MAFF, RGS3, ATF1, RGS4, ATF3, ATF4, FOS, GRK5, IL6

WP2895

Differentiation of white and brown adipocyte

WikiPathways

MPZL2, PPARGC1A, CEBPB, CEBPG, ZNF423, SMAD5, SMAD9, ZIC1, ADIPOQ, BMP4, BMP2, PPARG, PPARGC1B, LEP, SMAD1