| Pathway ID |
Pathway Term |
Pathway Source |
Proteins |
|
h_tsp1Pathway
|
TSP-1 Induced Apoptosis in Microvascular Endothelial Cell
|
BioCarta
|
CD36,
MAPK14,
FOS,
FYN,
JUN,
THBS1
|
|
h_tubbyPathway
|
G-Protein Signaling Through Tubby Proteins
|
BioCarta
|
GNAQ,
GNB1,
HTR2C,
PLCB1
|
|
h_ucalpainPathway
|
uCalpain and friends in Cell spread
|
BioCarta
|
PTK2,
ACTN1,
ACTN2,
RHOA,
ITGB1,
ITGB3,
RAC1,
TLN1,
EZR
|
|
h_vdrPathway
|
Control of Gene Expression by Vitamin D Receptor
|
BioCarta
|
CREBBP,
HDAC1,
ACTL6A,
EP300,
PRMT1,
SMARCA4,
SMARCC1,
SMARCC2,
SMARCD1,
TSC2,
VDR,
NCOA3,
ARID1A,
NCOA1,
KAT2B,
BAZ1B,
NCOR1,
CHAF1A,
CARM1,
NCOA2,
SUPT16H
|
|
h_vegfPathway
|
VEGF, Hypoxia, and Angiogenesis
|
BioCarta
|
ARNT,
EIF1AX,
EIF2S1,
EIF2B1,
EIF2S3,
ELAVL1,
FLT4,
HIF1A,
NOS3,
PIK3CA,
PIK3CG,
PIK3R1,
PRKCA,
PRKCB,
PTK2,
VEGFA,
EIF2B4,
EIF2B3,
EIF2B5,
EIF1
|
|
h_vifPathway
|
HIV-1 defeats host-mediated resistance by CEM15,
|
BioCarta
|
CD4,
CXCR4
|
|
h_vipPathway
|
Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells
|
BioCarta
|
MYC,
CALM2,
CALM3,
EGR2,
EGR3,
GNAQ,
NFATC1,
NFATC2,
NFKB1,
PPP3CA,
PRKAR1A,
PRKAR2A,
PRKAR2B,
RELA
|
|
h_vitCBPathway
|
Vitamin C in the Brain
|
BioCarta
|
COL4A2,
COL4A3,
COL4A6,
P4HB,
SLC2A1,
SLC2A3,
SLC23A2
|
|
h_vobesityPathway
|
Visceral Fat Deposits and the Metabolic Syndrome
|
BioCarta
|
NR3C1,
HSD11B1,
LPL,
PPARG,
TNF,
ADIPOQ,
RETN
|
|
h_wnt-lrp6Pathway
|
Wnt/LRP6 Signalling
|
BioCarta
|
LRP6,
DKK1,
DKK2
|
|
h_wntPathway
|
WNT Signaling Pathway
|
BioCarta
|
APC,
CREBBP,
CSNK1A1,
CSNK1D,
CTNNB1,
GSK3B,
HDAC1,
SMAD4,
MYC,
PPARD,
MAP3K7,
HNF1A,
TLE1,
AXIN1,
BTRC,
TAB1,
WIF1,
NLK
|
|
h_WNVpathway
|
West Nile Virus
|
BioCarta
|
CASP9,
EEF1A1,
TIA1
|
|
hsa00010
|
Glycolysis / Gluconeogenesis
|
KEGG
|
ADH1B,
ADH7,
DLAT,
DLD,
ENO1,
ENO2,
ENO3,
ALDH2,
ALDH1B1,
ALDH1A3,
FBP1,
ALDH3B2,
ALDH9A1,
ALDH3A2,
ALDOA,
ALDOC,
G6PC,
GAPDH,
GPI,
HK1,
LDHA,
LDHB,
ALDH7A1,
PCK1,
PCK2,
PDHA1,
PDHB,
PFKL,
PGAM1,
PGK1,
PGM1,
PKM,
PGM2,
ACSS2,
BPGM,
TPI1,
HKDC1,
ACSS1,
FBP2,
G6PC3,
MINPP1
|
|
hsa00020
|
Citrate cycle (TCA cycle)
|
KEGG
|
DLAT,
DLD,
DLST,
FH,
IDH1,
IDH2,
IDH3B,
MDH1,
MDH2,
OGDH,
ACO2,
PC,
PCK1,
PCK2,
PDHA1,
PDHB,
SDHA,
SDHB,
SDHC,
SUCLG1,
SUCLA2
|
|
hsa00030
|
Pentose phosphate pathway
|
KEGG
|
FBP1,
ALDOA,
ALDOC,
G6PD,
PGLS,
GPI,
IDNK,
DERA,
PFKL,
PGD,
PGM1,
PGM2,
PRPS1,
PRPS2,
TALDO1,
TKT,
FBP2,
RGN,
H6PD
|
|
hsa00040
|
Pentose and glucuronate interconversions
|
KEGG
|
AKR1B1,
CRYL1,
DCXR,
SORD,
UGDH,
UGP2,
UGT2B4,
UGT2A3,
KL
|
|
hsa00051
|
Fructose and mannose metabolism
|
KEGG
|
FBP1,
ALDOA,
ALDOC,
AKR1B1,
TKFC,
GMDS,
GMPPB,
HK1,
PFKFB1,
PFKFB2,
PFKFB3,
PFKFB4,
PFKL,
PMM2,
ENOSF1,
SORD,
TPI1,
HKDC1,
FBP2
|
|
hsa00052
|
Galactose metabolism
|
KEGG
|
AKR1B1,
G6PC,
GAA,
GALE,
GALT,
B4GALT1,
HK1,
LCT,
PFKL,
PGM1,
PGM2,
UGP2,
HKDC1,
MGAM,
G6PC3
|
|
hsa00053
|
Ascorbate and aldarate metabolism
|
KEGG
|
ALDH2,
ALDH1B1,
ALDH9A1,
ALDH3A2,
ALDH7A1,
MIOX,
UGDH,
UGT2B4,
UGT2A3,
RGN
|
|
hsa00061
|
Fatty acid biosynthesis
|
KEGG
|
ACSL1,
ACSL4,
FASN,
ACSL6,
ACACB
|
|
hsa00062
|
Fatty acid elongation
|
KEGG
|
ACOT7,
ACOT4,
ECHS1,
HACD2,
HADHB,
HADH,
HACD4,
MECR,
HSD17B12,
HACD3,
PPT1,
ELOVL5,
ELOVL1,
ELOVL4,
ELOVL6,
ELOVL7,
HACD1,
PPT2
|
|
hsa00071
|
Fatty acid degradation
|
KEGG
|
ECI2,
ADH1B,
ADH7,
CPT1A,
CPT1B,
ECI1,
ECHS1,
ALDH2,
ACSL1,
ACSL4,
ALDH1B1,
ALDH9A1,
ALDH3A2,
ACSL6,
HADHB,
HADH,
ACADSB,
ACADVL,
ACAT2,
ALDH7A1,
ACOX1,
ACOX3
|
|
hsa00072
|
Synthesis and degradation of ketone bodies
|
KEGG
|
HMGCL,
HMGCS1,
ACAT2,
OXCT1,
BDH2
|
|
hsa00100
|
Steroid biosynthesis
|
KEGG
|
EBP,
CYP2R1,
CYP27B1,
CYP51A1,
DHCR7,
DHCR24,
FDFT1,
LIPA,
LSS,
NSDHL,
HSD17B7,
MSMO1,
SC5D,
SOAT1,
SQLE,
TM7SF2
|
|
hsa00120
|
Primary bile acid biosynthesis
|
KEGG
|
ACOT8,
CYP8B1,
HSD17B4,
SCP2,
HSD3B7,
ACOX2,
CH25H
|
|
hsa00130
|
Ubiquinone and other terpenoid-quinone biosynthesis
|
KEGG
|
NQO1,
GGCX,
COQ2,
COQ3,
VKORC1
|
|
hsa00140
|
Steroid hormone biosynthesis
|
KEGG
|
COMT,
CYP1A1,
CYP1B1,
CYP3A7,
CYP2E1,
CYP3A4,
CYP3A5,
CYP11A1,
CYP11B1,
CYP11B2,
CYP17A1,
CYP19A1,
CYP21A2,
AKR1C1,
AKR1C2,
HSD3B1,
HSD3B2,
HSD11B1,
HSD11B2,
HSD17B1,
HSD17B2,
STS,
HSD17B12,
HSD17B7,
SRD5A1,
SRD5A2,
SULT1E1,
UGT2B4,
UGT2A3,
HSD17B6,
AKR1C3
|
|
hsa00190
|
Oxidative phosphorylation
|
KEGG
|
COX17,
TCIRG1,
ATP5H,
ATP5L,
UQCR11,
NDUFA11,
COX5B,
COX6A1,
COX6B1,
COX6C,
COX7B,
COX7C,
COX11,
CYC1,
COX7B2,
ATP6V1C2,
PPA2,
UQCRQ,
UQCR10,
UQCRHL,
NDUFA1,
NDUFA2,
NDUFA4,
NDUFA5,
NDUFA7,
NDUFA10,
NDUFAB1,
NDUFB4,
NDUFB6,
NDUFB7,
NDUFB8,
NDUFB10,
NDUFS1,
NDUFS2,
NDUFS4,
NDUFS6,
NDUFS8,
NDUFV2,
NDUFV3,
ATP12A,
ATP5C1,
NDUFA13,
ATP5D,
ATP6V1D,
ATP5E,
ATP6V1H,
ATP5G2,
ATP5G3,
ATP5I,
ATP5J,
ATP6V1B2,
ATP6V1C1,
ATP6V1G2,
ATP6V0A1,
ATP5O,
NDUFB11,
SDHA,
SDHB,
SDHC,
UQCRB,
UQCRC1,
UQCRC2,
UQCRFS1,
UQCRH,
ATP6V0E1,
ATP6V0D1,
ATP6V1F,
COX5A,
ATP6V1G1
|
|
hsa00220
|
Arginine biosynthesis
|
KEGG
|
GLS,
GLUD2,
GOT2,
ASS1,
NOS3,
GPT2
|
|
hsa00230
|
Purine metabolism
|
KEGG
|
ADA,
NME6,
PAICS,
POLR3F,
POLR3G,
POLR3C,
POLD3,
ADCY3,
NUDT5,
ADCY7,
ADCY9,
ADSSL1,
NUDT16,
ADSL,
AK8,
ADSS,
DCK,
DGUOK,
AK1,
AK4,
FHIT,
ENPP4,
POLA2,
POLR2J2,
POLR1A,
GART,
PDE7B,
AMPD3,
GMPR,
GUK1,
NME7,
GUCY2D,
NT5C,
ZNRD1,
APRT,
NME1,
NME4,
PNP,
NPR2,
NT5E,
AK3,
POLR1D,
PDE3A,
PDE3B,
PDE4C,
PDE4D,
PDE6D,
PDE7A,
PDE8A,
PDE9A,
ENPP1,
ENPP3,
POLR3K,
PFAS,
PGM1,
PKM,
NUDT9,
POLE3,
POLA1,
POLD1,
POLE,
POLE2,
POLR2A,
POLR2B,
POLR2D,
POLR2E,
POLR2G,
POLR2I,
POLR2J,
POLR2K,
POLR2L,
PPAT,
PGM2,
PRIM1,
PRIM2,
POLR3B,
PRPS1,
PRPS2,
POLE4,
POLD4,
PRUNE,
RRM1,
RRM2,
POLR1E,
NME2,
XDH,
POLR3GL,
PDE8B,
PDE5A,
PNPT1,
GMPS,
PAPSS2,
POLR1C,
ENTPD6,
ENTPD3
|
|
hsa00232
|
Caffeine metabolism
|
KEGG
|
CYP2A6,
XDH
|
|
hsa00240
|
Pyrimidine metabolism
|
KEGG
|
NME6,
POLR3F,
POLR3G,
POLR3C,
POLD3,
CMPK2,
UPRT,
CTPS1,
UPP2,
DCK,
DCTD,
DHODH,
DPYD,
DTYMK,
DUT,
TYMP,
POLA2,
POLR2J2,
POLR1A,
NME7,
NT5C,
ZNRD1,
NME1,
NME4,
PNP,
NT5E,
POLR1D,
ENPP1,
ENPP3,
CMPK1,
POLR3K,
POLE3,
POLA1,
POLD1,
POLE,
POLE2,
POLR2A,
POLR2B,
POLR2D,
POLR2E,
POLR2G,
POLR2I,
POLR2J,
POLR2K,
POLR2L,
UCKL1,
PRIM1,
PRIM2,
POLR3B,
CTPS2,
POLE4,
POLD4,
RRM1,
RRM2,
POLR1E,
NME2,
TK1,
TK2,
TXNRD1,
TYMS,
UCK2,
UMPS,
UPP1,
CAD,
DCTPP1,
UCK1,
POLR3GL,
PNPT1,
POLR1C,
ENTPD6,
ENTPD3
|
|
hsa00250
|
Alanine, aspartate and glutamate metabolism
|
KEGG
|
ADSSL1,
ADSL,
ADSS,
ABAT,
AGXT,
GFPT1,
GLS,
GLUD2,
GOT2,
ASNS,
ASS1,
PPAT,
RIMKLB,
CAD,
GPT2
|
|
hsa00260
|
Glycine, serine and threonine metabolism
|
KEGG
|
CTH,
DLD,
SARDH,
AGXT,
PHGDH,
GATM,
GCSH,
DMGDH,
PSAT1,
AOC2,
MAOA,
MAOB,
ALDH7A1,
PIPOX,
PGAM1,
SHMT1,
BPGM,
AOC3,
CBS,
GRHPR
|
|
hsa00270
|
Cysteine and methionine metabolism
|
KEGG
|
CDO1,
AHCYL1,
CTH,
DNMT1,
DNMT3B,
AHCY,
AMD1,
GCLC,
GCLM,
MAT2B,
GOT2,
LDHA,
LDHB,
MAT2A,
MDH1,
MDH2,
MPST,
MTAP,
MTR,
ADI1,
BCAT1,
SRM,
CBS
|
|
hsa00280
|
Valine, leucine and isoleucine degradation
|
KEGG
|
HIBADH,
DBT,
DLD,
ABAT,
ECHS1,
ALDH2,
ALDH1B1,
ALDH9A1,
ALDH3A2,
HIBCH,
HSD17B10,
HADHB,
HADH,
HMGCL,
HMGCS1,
AOX1,
ACADSB,
ACAT2,
ALDH6A1,
ALDH7A1,
OXCT1,
PCCA,
AUH,
MCCC1,
BCAT1,
BCKDHA,
BCKDHB,
MCCC2,
AACS,
MCEE
|
|
hsa00290
|
Valine, leucine and isoleucine biosynthesis
|
KEGG
|
BCAT1
|
|
hsa00300
|
Lysine biosynthesis
|
KEGG
|
ALDH7A1
|
|
hsa00310
|
Lysine degradation
|
KEGG
|
AASS,
EHMT2,
DLST,
ECHS1,
EZH1,
EZH2,
ALDH2,
ALDH1B1,
ALDH9A1,
ALDH3A2,
HADH,
KMT5A,
ACAT2,
OGDH,
ALDH7A1,
KMT5B,
PIPOX,
PLOD1,
PLOD2,
WHSC1L1,
ASH1L,
KMT2E,
KMT2C,
WHSC1,
PRDM2,
SUV39H2,
SETD7,
SETDB2,
KMT5C,
PHYKPL,
PRDM6,
KMT2B
|
|
hsa00330
|
Arginine and proline metabolism
|
KEGG
|
SAT2,
L3HYPDH,
CKB,
CKMT2,
ALDH2,
ALDH1B1,
ALDH9A1,
ALDH3A2,
AMD1,
GATM,
GOT2,
MAOA,
MAOB,
NOS3,
ODC1,
ALDH7A1,
P4HA1,
LAP3,
CKMT1A,
PRODH,
ALDH18A1,
SAT1,
PYCRL,
SRM,
AGMAT,
P4HA2
|
|
hsa00340
|
Histidine metabolism
|
KEGG
|
ALDH2,
ALDH1B1,
ALDH1A3,
ALDH3B2,
ALDH9A1,
ALDH3A2,
HNMT,
MAOA,
MAOB,
ALDH7A1
|
|
hsa00350
|
Tyrosine metabolism
|
KEGG
|
ADH1B,
ADH7,
COMT,
FAH,
ALDH1A3,
ALDH3B2,
GOT2,
GSTZ1,
HGD,
AOC2,
AOX1,
MAOA,
MAOB,
MIF,
PNMT,
TH,
TYR,
AOC3
|
|
hsa00360
|
Phenylalanine metabolism
|
KEGG
|
ALDH1A3,
ALDH3B2,
GOT2,
AOC2,
MAOA,
MAOB,
MIF,
AOC3
|
|
hsa00380
|
Tryptophan metabolism
|
KEGG
|
TPH2,
CYP1A1,
CYP1B1,
ECHS1,
ALDH2,
ALDH1B1,
ALDH9A1,
ALDH3A2,
HADH,
AOX1,
ACAT2,
MAOA,
MAOB,
OGDH,
ALDH7A1,
KMO,
KYNU
|
|
hsa00400
|
Phenylalanine, tyrosine and tryptophan biosynthesis
|
KEGG
|
GOT2
|
|
hsa00410
|
beta-Alanine metabolism
|
KEGG
|
ABAT,
DPYD,
ECHS1,
ALDH2,
ALDH1B1,
ALDH1A3,
ALDH3B2,
ALDH9A1,
ALDH3A2,
HIBCH,
AOC2,
ALDH6A1,
ALDH7A1,
SRM,
AOC3
|
|
hsa00430
|
Taurine and hypotaurine metabolism
|
KEGG
|
CDO1,
GGT7,
CSAD
|
|
hsa00440
|
Phosphonate and phosphinate metabolism
|
KEGG
|
CEPT1,
PCYT1A,
PCYT2,
EPT1,
PCYT1B
|
|
hsa00450
|
Selenocompound metabolism
|
KEGG
|
CTH,
SEPHS1,
MTR,
SEPSECS,
SCLY,
TXNRD1,
PAPSS2
|
|
hsa00471
|
D-Glutamine and D-glutamate metabolism
|
KEGG
|
GLS,
GLUD2
|
|
hsa00480
|
Glutathione metabolism
|
KEGG
|
GSTO2,
G6PD,
GGT7,
OPLAH,
GCLC,
GCLM,
GPX1,
GPX3,
GPX4,
GPX7,
GSR,
GSTA1,
GSTA4,
GSTM1,
GSTM2,
GSTM3,
GSTM4,
GSTP1,
GSTT1,
GSTT2,
IDH1,
IDH2,
GSTK1,
MGST1,
MGST2,
MGST3,
GPX8,
ODC1,
LAP3,
PGD,
RRM1,
RRM2,
SRM,
GSTO1
|
|
hsa00500
|
Starch and sucrose metabolism
|
KEGG
|
AGL,
G6PC,
GAA,
GBE1,
AMY2B,
GPI,
GYS1,
GYS2,
HK1,
ENPP1,
ENPP3,
PGM1,
PGM2,
PYGB,
PYGM,
UGP2,
HKDC1,
GYG2,
MGAM,
G6PC3
|
|
hsa00510
|
N-Glycan biosynthesis
|
KEGG
|
MAN1B1,
MGAT4B,
MGAT4A,
ALG10B,
MGAT5B,
DAD1,
DDOST,
STT3B,
GANAB,
FUT8,
B4GALT1,
ALG6,
STT3A,
MAN1A1,
MAN2A2,
MGAT2,
DPM3,
MAN1C1,
ST6GAL1,
ALG8,
ALG9,
ALG13,
ST6GAL2
|
|
hsa00511
|
Other glycan degradation
|
KEGG
|
MAN2B2,
FUCA1,
FUCA2,
HEXA,
MAN2B1,
NEU1,
GBA2,
ENGASE
|
|
hsa00512
|
Mucin type O-glycan biosynthesis
|
KEGG
|
GALNT5,
GALNT15,
GALNT1,
GALNT2,
GALNT7,
GALNT10,
ST3GAL1,
ST3GAL2,
GALNT14,
GALNT4,
B4GALT5
|
|
hsa00514
|
Other types of O-glycan biosynthesis
|
KEGG
|
POMT1,
B4GALT1,
RFNG,
ST6GAL1,
ST3GAL3,
ST6GAL2,
OGT
|
|
hsa00515
|
Mannose type O-glycan biosynthesis
|
KEGG
|
POMT1,
B4GAT1,
MGAT5B,
FUT4,
B4GALT1,
ST3GAL3,
FKRP,
POMK,
POMGNT2,
LARGE
|
|
hsa00520
|
Amino sugar and nucleotide sugar metabolism
|
KEGG
|
GNPDA1,
GNE,
CHIT1,
CYB5R3,
GALE,
GALT,
GFPT1,
GMDS,
GPI,
GMPPB,
HEXA,
HK1,
PGM1,
PMM2,
PGM2,
CMAS,
UAP1,
UGDH,
UGP2,
UXS1,
HKDC1,
NPL
|
|
hsa00524
|
Neomycin, kanamycin and gentamicin biosynthesis
|
KEGG
|
HK1,
HKDC1
|
|
hsa00531
|
Glycosaminoglycan degradation
|
KEGG
|
HPSE,
HGSNAT,
GALNS,
GNS,
HEXA,
ARSB,
NAGLU,
SGSH,
SPAM1,
HYAL2
|
|
hsa00532
|
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
|
KEGG
|
CHSY1,
DSE,
CHSY3,
CHST11,
CHST15,
CSGALNACT1,
CHST7,
XYLT2,
CHST3
|
|
hsa00533
|
Glycosaminoglycan biosynthesis - keratan sulfate
|
KEGG
|
CHST4,
B3GNT2,
FUT8,
B4GALT1,
CHST6,
ST3GAL1,
ST3GAL2,
ST3GAL3,
B4GALT4,
B3GNT7,
CHST2
|
|
hsa00534
|
Glycosaminoglycan biosynthesis - heparan sulfate / heparin
|
KEGG
|
EXT1,
EXT2,
NDST1,
XYLT2,
HS6ST2,
HS6ST1,
HS2ST1,
HS3ST3B1,
HS3ST1
|
|
hsa00561
|
Glycerolipid metabolism
|
KEGG
|
MGLL,
MBOAT2,
GPAT4,
DGKK,
DGKH,
ALDH2,
ALDH1B1,
ALDH9A1,
ALDH3A2,
AKR1B1,
LPIN1,
LCLAT1,
TKFC,
GK,
LPL,
ALDH7A1,
AGPAT3,
AGPAT4,
PNPLA2,
GPAM,
PNPLA3,
DGAT2,
GPAT3,
DGKZ,
PLPP1,
PLPP3,
LIPG
|
|
hsa00562
|
Inositol phosphate metabolism
|
KEGG
|
PIKFYVE,
PLCB1,
PIP5K1C,
IMPA1,
INPP1,
INPP4A,
INPP5A,
INPP5D,
ITPK1,
ITPKA,
ALDH6A1,
MTM1,
OCRL,
ISYNA1,
INPP5K,
PIK3C2A,
PIK3C3,
PIK3CA,
PIK3CB,
PIK3CD,
PIK3CG,
PI4KB,
PIP4K2A,
PLCD1,
PLCG2,
MIOX,
INPP5E,
PTEN,
TPI1,
PIP5K1B,
PIP4K2B,
MTMR1,
INPP4B,
SYNJ1,
SYNJ2,
MTMR2,
MTMR4,
MINPP1
|
|
hsa00563
|
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
|
KEGG
|
PIGK,
PIGU,
GPLD1,
PIGW,
PIGT,
PIGA,
PIGC,
PIGF,
PIGH,
PIGG,
PIGX,
PGAP1,
PIGY
|
|
hsa00564
|
Glycerophospholipid metabolism
|
KEGG
|
LPCAT3,
CEPT1,
CDS1,
PEMT,
LYPLA1,
PLA2G16,
CHKA,
CHKB,
LYPLA2,
MBOAT2,
GPAT4,
DGKK,
DGKH,
LPIN1,
LCLAT1,
GPD2,
PCYT1A,
PLA2G2A,
PLA2G4A,
PLA2G5,
PLD1,
CRLS1,
LPCAT2,
ETNK1,
AGPAT3,
AGPAT4,
GPAM,
PCYT2,
MBOAT7,
PLA2G12A,
GNPAT,
GPAT3,
DGKZ,
EPT1,
PLA2G4C,
PLPP1,
PLPP3,
CDS2,
PCYT1B,
PGS1,
PTDSS1,
LPGAT1
|
|
hsa00565
|
Ether lipid metabolism
|
KEGG
|
CEPT1,
PLA2G16,
PAFAH1B2,
PAFAH1B3,
ENPP2,
PLA2G2A,
PLA2G4A,
PLA2G5,
PLD1,
LPCAT2,
PLA2G7,
PLA2G12A,
AGPS,
EPT1,
PLA2G4C,
PLPP1,
PLPP3
|
|
hsa00590
|
Arachidonic acid metabolism
|
KEGG
|
PTGES3,
PLA2G16,
CYP2U1,
CYP2B6,
CYP2C9,
CYP2E1,
ALOX5,
ALOX15,
GPX1,
GPX3,
GPX7,
GPX8,
PLA2G2A,
PLA2G4A,
PLA2G5,
PTGDS,
PTGIS,
PTGS1,
PTGS2,
PLA2G12A,
PLA2G4C,
AKR1C3,
CBR1,
PTGES
|
|
hsa00591
|
Linoleic acid metabolism
|
KEGG
|
PLA2G16,
CYP2C9,
CYP2E1,
CYP3A4,
ALOX15,
PLA2G2A,
PLA2G4A,
PLA2G5,
PLA2G12A,
PLA2G4C
|
|
hsa00592
|
alpha-Linolenic acid metabolism
|
KEGG
|
PLA2G16,
ACOX1,
PLA2G2A,
PLA2G4A,
PLA2G5,
PLA2G12A,
ACOX3,
PLA2G4C,
FADS2
|
|
hsa00600
|
Sphingolipid metabolism
|
KEGG
|
SGPP2,
SGMS2,
CERS6,
GALC,
SGMS1,
ARSA,
ASAH1,
NEU1,
SMPD4,
GBA2,
UGCG,
CERS4,
PLPP1,
PLPP3,
SPHK1,
CERS5,
B4GALT6,
SPTLC2
|
|
hsa00601
|
Glycosphingolipid biosynthesis - lacto and neolacto series
|
KEGG
|
ST3GAL6,
B3GNT2,
FUT1,
FUT2,
FUT4,
FUT7,
GCNT2,
B4GALT1,
ST3GAL4,
ST3GAL3,
B3GNT5,
B4GALT4,
B3GALT2
|
|
hsa00603
|
Glycosphingolipid biosynthesis - globo and isoglobo series
|
KEGG
|
FUT1,
FUT2,
HEXA,
ST3GAL1,
ST3GAL2
|
|
hsa00604
|
Glycosphingolipid biosynthesis - ganglio series
|
KEGG
|
ST6GALNAC4,
HEXA,
ST3GAL1,
ST3GAL2,
ST6GALNAC5,
B3GALT4,
SLC33A1
|
|
hsa00620
|
Pyruvate metabolism
|
KEGG
|
ME3,
DLAT,
DLD,
ALDH2,
ALDH1B1,
ALDH9A1,
ALDH3A2,
FH,
GLO1,
HAGH,
ACACB,
ACAT2,
LDHA,
LDHB,
MDH1,
MDH2,
ME2,
ALDH7A1,
PC,
PCK1,
PCK2,
PDHA1,
PDHB,
PKM,
ACSS2,
ACSS1,
GRHPR,
ACYP1
|
|
hsa00630
|
Glyoxylate and dicarboxylate metabolism
|
KEGG
|
DLD,
AGXT,
GCSH,
ACAT2,
MDH1,
MDH2,
ACO2,
PCCA,
HAO2,
SHMT1,
MCEE,
GRHPR
|
|
hsa00640
|
Propanoate metabolism
|
KEGG
|
DBT,
DLD,
ABAT,
ECHS1,
HIBCH,
ACACB,
ACAT2,
LDHA,
LDHB,
ALDH6A1,
PCCA,
ECHDC1,
ACSS2,
BCKDHA,
BCKDHB,
ACSS3,
ACSS1,
MCEE,
SUCLG1,
SUCLA2
|
|
hsa00650
|
Butanoate metabolism
|
KEGG
|
ABAT,
ECHS1,
HADH,
HMGCL,
HMGCS1,
ACAT2,
OXCT1,
BDH2,
ACSM3,
AACS
|
|
hsa00670
|
One carbon pool by folate
|
KEGG
|
MTHFS,
MTHFD2,
ALDH1L1,
MTFMT,
ALDH1L2,
DHFR,
MTHFD1L,
GART,
MTHFD2L,
MTHFD1,
MTHFR,
MTR,
SHMT1,
TYMS
|
|
hsa00730
|
Thiamine metabolism
|
KEGG
|
AK8,
AK1,
AK4,
ALPL,
TPK1
|
|
hsa00740
|
Riboflavin metabolism
|
KEGG
|
ENPP1,
ENPP3,
RFK,
BLVRB
|
|
hsa00750
|
Vitamin B6 metabolism
|
KEGG
|
PSAT1,
AOX1,
PDXK
|
|
hsa00760
|
Nicotinate and nicotinamide metabolism
|
KEGG
|
NAMPT,
NADK2,
QPRT,
NT5C,
AOX1,
NMNAT3,
NNMT,
PNP,
NT5E,
ENPP1,
ENPP3,
NMRK1,
NADSYN1
|
|
hsa00770
|
Pantothenate and CoA biosynthesis
|
KEGG
|
DPYD,
ENPP1,
ENPP3,
BCAT1,
AASDHPPT,
PANK3,
PANK2,
COASY,
VNN1
|
|
hsa00785
|
Lipoic acid metabolism
|
KEGG
|
LIPT1
|
|
hsa00790
|
Folate biosynthesis
|
KEGG
|
GPHN,
DHFR,
ALPL,
QDPR,
GGH
|
|
hsa00830
|
Retinol metabolism
|
KEGG
|
DHRS9,
DHRS4,
ADH1B,
ADH7,
CYP1A1,
CYP2A6,
CYP3A7,
CYP2B6,
CYP2C9,
RDH10,
CYP3A4,
CYP3A5,
CYP26A1,
ALDH1A1,
AOX1,
RDH11,
CYP26B1,
UGT2B4,
UGT2A3,
HSD17B6,
ALDH1A2,
DHRS3
|
|
hsa00860
|
Porphyrin and chlorophyll metabolism
|
KEGG
|
EARS2,
CPOX,
EPRS,
ALAD,
FXN,
HCCS,
HMOX1,
MMAB,
BLVRB,
UGT2B4,
UROD,
UGT2A3,
HEPH
|
|
hsa00900
|
Terpenoid backbone biosynthesis
|
KEGG
|
FDPS,
ICMT,
PDSS1,
HMGCR,
HMGCS1,
IDI1,
ACAT2,
MVD,
MVK,
PCYOX1,
PDSS2,
IDI2,
RCE1
|
|
hsa00910
|
Nitrogen metabolism
|
KEGG
|
GLUD2,
CA13,
CA2,
CA3,
CA4,
CA8,
CA12
|
|
hsa00920
|
Sulfur metabolism
|
KEGG
|
ETHE1,
MPST,
CYCS,
SUOX,
PAPSS2
|
|
hsa00970
|
Aminoacyl-tRNA biosynthesis
|
KEGG
|
FARS2,
MTFMT,
EARS2,
DARS,
EPRS,
FARSA,
LARS2,
HARS2,
PARS2,
GATC,
HARS,
KARS,
SEPSECS,
GATB,
QRSL1,
RARS,
SARS,
TARS,
YARS
|
|
hsa00980
|
Metabolism of xenobiotics by cytochrome P450
|
KEGG
|
GSTO2,
ADH1B,
ADH7,
CYP1A1,
CYP1B1,
CYP2A6,
CYP2B6,
CYP2C9,
CYP2D6,
CYP2E1,
CYP3A4,
CYP3A5,
AKR1C1,
EPHX1,
ALDH1A3,
ALDH3B2,
GSTA1,
GSTA4,
GSTM1,
GSTM2,
GSTM3,
GSTM4,
GSTP1,
GSTT1,
GSTT2,
HSD11B1,
GSTK1,
MGST1,
MGST2,
MGST3,
SULT2A1,
UGT2B4,
UGT2A3,
AKR7A2,
CBR1,
GSTO1
|
|
hsa00982
|
Drug metabolism - cytochrome P450
|
KEGG
|
GSTO2,
ADH1B,
ADH7,
CYP2A6,
CYP2B6,
CYP2C9,
CYP2D6,
CYP2E1,
CYP3A4,
CYP3A5,
ALDH1A3,
ALDH3B2,
FMO2,
FMO4,
GSTA1,
GSTA4,
GSTM1,
GSTM2,
GSTM3,
GSTM4,
GSTP1,
GSTT1,
GSTT2,
AOX1,
GSTK1,
MAOA,
MAOB,
MGST1,
MGST2,
MGST3,
UGT2B4,
UGT2A3,
GSTO1
|
|
hsa00983
|
Drug metabolism - other enzymes
|
KEGG
|
UPP2,
CYP2A6,
CYP3A4,
DPYD,
TYMP,
UCKL1,
TK1,
TK2,
TPMT,
UGT2B4,
UCK2,
UMPS,
UPP1,
XDH,
UGT2A3,
UCK1,
GMPS
|
|
hsa01040
|
Biosynthesis of unsaturated fatty acids
|
KEGG
|
ACOT7,
ACOT4,
HACD2,
FADS1,
HACD4,
ACOX1,
HSD17B12,
HACD3,
ELOVL5,
SCD,
ELOVL6,
SCD5,
ACOX3,
HACD1,
FADS2
|
|
hsa01100
|
Metabolic pathways
|
KEGG
|
ADA,
ACOT8,
GNPDA1,
GNE,
PIGK,
COX17,
NAMPT,
AASS,
DHRS9,
NME6,
GPHN,
TCIRG1,
CDO1,
CEPT1,
CDS1,
PEMT,
ST3GAL6,
ATP5H,
POMT1,
MTHFS,
PAICS,
POLR3F,
POLR3G,
POLR3C,
ATP5L,
B3GNT2,
EBP,
POLD3,
PTGES3,
AHCYL1,
MTHFD2,
HPSE,
ME3,
DHRS4,
UQCR11,
B4GAT1,
HIBADH,
PLA2G16,
CHIT1,
CHKA,
CHKB,
GALNT5,
SAT2,
MAN1B1,
MGAT4B,
MGAT4A,
MGLL,
CYP2U1,
CKB,
CKMT2,
GALNT15,
CYP2R1,
TPH2,
ADSSL1,
ACOT4,
EARS2,
ADH1B,
NDUFA11,
PIGU,
CMPK2,
MBOAT2,
ADH7,
COMT,
COX5B,
NADK2,
COX6A1,
COX6B1,
COX6C,
COX7B,
COX7C,
COX11,
CPOX,
GPAT4,
HGSNAT,
DGKK,
UPRT,
ALG10B,
MGAT5B,
CTH,
CTPS1,
UPP2,
CYC1,
CYP1A1,
CYP2A6,
CYP3A7,
CYP2B6,
CYP2C9,
CYP2E1,
RDH10,
CYP3A4,
CYP3A5,
ADSL,
AK8,
CYP8B1,
CYP11A1,
CYP11B1,
CYP11B2,
CYP17A1,
CYP19A1,
CYP21A2,
ADSS,
CYP26A1,
CYP27B1,
CYP51A1,
DAD1,
DGKH,
DBT,
DCK,
DCTD,
DDOST,
SGMS2,
COX7B2,
DGUOK,
DHCR7,
DHCR24,
DHFR,
DHODH,
DLAT,
DLD,
DLST,
SARDH,
AGL,
DNMT1,
DNMT3B,
ABAT,
DPYD,
DTYMK,
DUT,
AGXT,
TYMP,
ECHS1,
AHCY,
STT3B,
ENO1,
ENO2,
ENO3,
AK1,
AK4,
EPRS,
ALAD,
EXT1,
EXT2,
ALDH1A1,
ALDH2,
ACSL1,
ACSL4,
FAH,
ALDH1B1,
FASN,
ALDH1A3,
FBP1,
ALDH3B2,
FDFT1,
FDPS,
ALDH9A1,
ALDH3A2,
ALDOA,
FH,
CHSY1,
SEPHS1,
ALDOC,
AKR1B1,
LPIN1,
GANAB,
PLCB1,
ACSL6,
PIP5K1C,
QPRT,
POLA2,
ALOX5,
ATP6V1C2,
ALOX15,
POLR2J2,
ALPL,
FUT1,
FUT2,
FUT4,
FUT7,
FUT8,
LCLAT1,
CERS6,
G6PC,
G6PD,
GAA,
PGLS,
GALC,
GALE,
GALNS,
POLR1A,
GALNT1,
GALNT2,
MTHFD1L,
GALT,
SGMS1,
GAPDH,
TKFC,
GART,
AMD1,
PHGDH,
HIBCH,
GATM,
GBE1,
GCNT2,
GCSH,
GFPT1,
B4GALT1,
GGT7,
TPK1,
UQCRQ,
ST6GALNAC4,
GK,
AMPD3,
COQ2,
GCLC,
GCLM,
MAT2B,
GLS,
GLUD2,
GMDS,
GNS,
AMY2B,
GOT2,
GPI,
GATC,
PIGW,
GSTZ1,
UQCR10,
GUK1,
NME7,
GMPPB,
ALG6,
DSE,
DMGDH,
PSAT1,
GYS1,
GYS2,
HSD17B10,
HADHB,
HADH,
HEXA,
HGD,
NT5C,
ZNRD1,
HK1,
AOC2,
HMGCL,
HMGCR,
HMGCS1,
AOX1,
HMOX1,
ACACB,
MMAB,
HSD3B1,
HSD3B2,
HSD11B1,
HSD17B1,
HSD17B2,
HSD17B4,
NDST1,
CHSY3,
IDH1,
IDH2,
IDH3B,
IDI1,
NMNAT3,
APRT,
ACADSB,
IMPA1,
INPP1,
INPP4A,
INPP5A,
ACADVL,
STT3A,
ITPK1,
ITPKA,
ACAT2,
LAMA3,
LCT,
LDHA,
LDHB,
LSS,
ARSB,
MAN1A1,
MAN2A2,
MAOA,
MAOB,
IDNK,
MAT2A,
MDH1,
MDH2,
MGAT2,
ASAH1,
ALDH6A1,
MPST,
ASNS,
UQCRHL,
MTHFD2L,
ASS1,
MTAP,
MTHFD1,
MTHFR,
MTM1,
MTR,
MVD,
MVK,
NAGLU,
NDUFA1,
NDUFA2,
NDUFA4,
NDUFA5,
NDUFA7,
NDUFA10,
NDUFAB1,
NDUFB4,
NDUFB6,
NDUFB7,
NDUFB8,
NDUFB10,
NDUFS1,
NDUFS2,
NDUFS4,
NDUFS6,
NDUFS8,
NDUFV2,
NDUFV3,
NME1,
NME4,
NNMT,
NOS3,
PNP,
NT5E,
OCRL,
ODC1,
OGDH,
ACO2,
ALDH7A1,
P4HA1,
PAFAH1B2,
PAFAH1B3,
NSDHL,
ATP5C1,
PC,
PCCA,
ACOX1,
PCK1,
LAP3,
PCK2,
NDUFA13,
POLR1D,
CRYL1,
MECR,
RDH11,
HSD17B12,
HAO2,
DCXR,
PIPOX,
ATP5D,
PCYT1A,
CSAD,
ATP6V1D,
ATP5E,
ISYNA1,
HSD17B7,
SCLY,
PDHA1,
LIPT1,
PIGT,
ATP6V1H,
PDHB,
ENPP1,
ENPP3,
ATP5G2,
CMPK1,
POLR3K,
INPP5K,
ATP5G3,
COQ3,
GALNT7,
GATB,
PFAS,
ATP5I,
PFKL,
ATP5J,
PGAM1,
PGD,
PGK1,
PGM1,
ATP6V1B2,
PIGA,
PIGC,
ATP6V1C1,
PIGF,
PIGH,
PIK3C2A,
PIK3C3,
PI4KB,
PKM,
PLA2G2A,
PLA2G4A,
PLA2G5,
PLCD1,
PLCG2,
PLD1,
ATP6V1G2,
ATP6V0A1,
PMM2,
ATP5O,
PNMT,
POLE3,
CYCS,
POLA1,
POLD1,
POLE,
POLE2,
POLG,
POLR2A,
POLR2B,
POLR2D,
POLR2E,
DPM3,
POLR2G,
POLR2I,
POLR2J,
POLR2K,
POLR2L,
PON1,
NDUFB11,
CRLS1,
PPAT,
CKMT1A,
AUH,
LPCAT2,
UCKL1,
PIGX,
NMRK1,
NADSYN1,
ADI1,
PGM2,
QRSL1,
RFK,
PPT1,
ETNK1,
GALNT10,
PRIM1,
PRIM2,
SMPD4,
POLR3B,
CSGALNACT1,
ACSS2,
CMAS,
PRODH,
PRPS1,
PRPS2,
CTPS2,
CYP26B1,
INPP5E,
POLE4,
AGPAT3,
AGPAT4,
BDH2,
MCCC1,
PNPLA2,
MAN1C1,
PTGDS,
PTGIS,
PTGS1,
PTGS2,
RIMKLB,
GPAM,
GBA2,
POLD4,
ALDH18A1,
PCYT2,
PYGB,
PYGM,
BCAT1,
QDPR,
BCKDHA,
BCKDHB,
REV3L,
RRM1,
RRM2,
ACSM3,
SAT1,
MSMO1,
SC5D,
SCP2,
SDHA,
SDHB,
SDHC,
MCCC2,
XYLT2,
POLR1E,
SGSH,
BLVRB,
SHMT1,
ST6GAL1,
ST3GAL1,
ST3GAL2,
ST3GAL4,
ST3GAL3,
PYCRL,
NME2,
TRAK2,
SORD,
UAP1,
SPAM1,
BPGM,
SQLE,
SRM,
SUOX,
TALDO1,
TH,
TK1,
TK2,
TKT,
TM7SF2,
TPI1,
TYMS,
TYR,
UGCG,
UGDH,
UGP2,
UGT2B4,
UCK2,
UMPS,
UPP1,
UQCRB,
UQCRC1,
UQCRC2,
UQCRFS1,
UQCRH,
UROD,
XDH,
CAD,
ALG8,
DCTPP1,
FKRP,
PLA2G7,
CERS4,
ACSS3,
GALNT14,
PANK3,
ALG9,
UGT2A3,
AGMAT,
ALG13,
PANK2,
PGAP1,
UXS1,
HKDC1,
HSD3B7,
PNPLA3,
COASY,
PLA2G12A,
ST6GALNAC5,
ACOX2,
ACOX3,
UCK1,
PIP5K1B,
B3GNT5,
POMK,
POLR3GL,
ACSS1,
ST6GAL2,
DGAT2,
MCEE,
GPT2,
GPAT3,
POMGNT2,
PIGY,
PHYKPL,
DGKZ,
AGPS,
EPT1,
KMO,
PDXK,
PLA2G4C,
PLPP1,
PLPP3,
HSD17B6,
AOC3,
AKR1C3,
HYAL2,
GALNT4,
B4GALT4,
B3GALT4,
B3GALT2,
CBR1,
CBS,
CDS2,
MTMR1,
FBP2,
SUCLG1,
SUCLA2,
INPP4B,
GMPS,
ALDH1A2,
SYNJ1,
SYNJ2,
SPHK1,
MTMR2,
GYG2,
KYNU,
MGAM,
P4HA2,
ATP6V0E1,
PAPSS2,
CERS5,
RGN,
MTMR4,
ATP6V0D1,
IDI2,
SLC33A1,
LARGE,
DHRS3,
G6PC3,
ATP6V1F,
B4GALT6,
KL,
PPT2,
COX5A,
GRHPR,
LIPG,
PCYT1B,
PGS1,
SPTLC2,
POLR1C,
PTGES,
ATP6V1G1,
MINPP1,
H6PD,
PRDX6,
PTDSS1
|
|
hsa01200
|
Carbon metabolism
|
KEGG
|
ME3,
DLAT,
DLD,
DLST,
AGXT,
ECHS1,
ENO1,
ENO2,
ENO3,
FBP1,
ALDOA,
FH,
ALDOC,
G6PD,
PGLS,
GAPDH,
TKFC,
PHGDH,
HIBCH,
GLUD2,
GOT2,
GPI,
PSAT1,
HK1,
IDH1,
IDH2,
IDH3B,
ACAT2,
IDNK,
MDH1,
MDH2,
ME2,
ALDH6A1,
MTHFR,
OGDH,
ACO2,
PC,
PCCA,
HAO2,
PDHA1,
PDHB,
PFKL,
PGAM1,
PGD,
PGK1,
PKM,
ACSS2,
PRPS1,
PRPS2,
SDHA,
SDHB,
SDHC,
SHMT1,
TALDO1,
TKT,
TPI1,
HKDC1,
ACSS1,
MCEE,
GPT2,
FBP2,
SUCLG1,
SUCLA2,
RGN,
H6PD
|
|
hsa01210
|
2-Oxocarboxylic acid metabolism
|
KEGG
|
GOT2,
IDH1,
IDH2,
IDH3B,
ACO2,
BCAT1,
GPT2
|