pathway_id,pathway_term,pathway_source,proteins
h_gsk3Pathway,"Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages",BioCarta,AKT1;APC;CD14;CTNNB1;GNAI1;GSK3B;IRAK1;NFKB1;PIK3CA;PIK3R1;RELA;TLR4;AXIN1;TOLLIP;TIRAP;GJA1
h_il1rPathway,"Signal transduction through IL1R",BioCarta,MAPK14;IL1A;IL1B;IL1R1;IL6;IRAK1;JUN;NFKB1;MAPK8;MAP2K6;RELA;MAP3K7;TGFB1;TGFB2;TNF;TAB1;TOLLIP;IL1RAP;IL1RN;IRAK2;IRAK3
h_tollPathway,"Toll-Like Receptor Pathway",BioCarta,MAPK14;FOS;JUN;NFKB1;RELA;MAP3K7;TAB1;CD14;ELK1;IRAK1;PPARA;MAPK8;MAP2K6;TLR2;TLR3;TLR4;TOLLIP;TIRAP
hsa04620,"Toll-like receptor signaling pathway",KEGG,"AKT3;TAB1;TIRAP;MAP3K8;MAPK14;CTSK;AKT1;AKT2;FOS;TBK1;IFNA1 ;IFNA16;IFNAR1;IFNAR2;IL1B;IL6;CXCL8;IL12A;IRAK1;JUN;NFKB1;PIK3CA;PIK3CB;PIK3CD;PIK3R1;TOLLIP;MAPK1;MAPK3;MAPK8;MAPK9;MAPK13;MAP2K1;MAP2K2;MAP2K6;MAP2K7;RAC1;RELA;CCL3;CCL4;CCL5;SPP1;MAP3K7;TLR1;TLR2;TLR3;TLR4;TLR5;TNF;CASP8;RIPK1;FADD;CD14"
WP1449,"Regulation of toll-like receptor signaling pathway",WikiPathways,"JUN;CCL3;CCL5;CCL4;RIPK1;SQSTM1;TREM1;PELI1;PELI2;MAP3K7;MAP3K8;AKT1;AKT2;TRAFD1;CD14;MLST8;CTNNAL1;AKT3;SPP1;NFKB1;TLR5;TIRAP;MAPK14;RELA;SOCS1;TOLLIP;RNF216;PLK1;SARM1;SMAD6;CASP8;TAB3;SIGIRR;TNF;FADD;MBL2;CXCL8;MAPK9;MAP2K2;MAPK13;IL12A;MAP2K1;MAP2K7;MAP2K6;FBXW5;IFNA1 ;IFNA16;TNFAIP3;MAPK3;RAC1;MAPK1;MAPK8;SYK;IFNAR1;IFNAR2;CYLD;IRAK2;IL1B;IRAK1;ZMYND11;IRAK3;TBK1;PIK3CA;PIK3CB;PIK3CD;TLR3;TLR4;TAB1;TLR1;FOS;TLR2;PIK3CG;PIK3R1;IL6"
WP1772,"Apoptosis Modulation and Signaling",WikiPathways,JUN;CASP9;CASP8;BIRC5;TNFSF10;BIRC3;XIAP;CRADD;FADD;CFLAR;RIPK1;PRKD1;BAD;IL1R2;MAP3K5;BID;HSPA1A;BAX;CASP4;CASP6;TNFRSF1B;CASP1;TNFRSF11B;PMAIP1;PEA15;MAPK3;NFKB1;MAPK8;BNIP3;BOK;TOLLIP;BBC3;TNFRSF10C;HN1;IL1R1;IRAK1;BCL2L11;TRADD;AIFM2;TNFRSF25;BCL2;BCL2L2;TP53;MCL1;FAS;DFFA;CYCS;FOS;AIFM1
WP195,"IL-1 signaling pathway",WikiPathways,JUN;PTPN11;TAB3;CCL2;SQSTM1;PELI1;MAPK9;PELI2;MAP2K2;MAP2K1;MAP2K7;MAP3K7;MAP2K6;IL1A;AKT1;MAPK3;NFKB1;MAPK1;MAPK8;MAPK14;RELA;MAPKAPK2;HSPB2;TOLLIP;UBE2V1;IL1RAP;IRAK2;IL1B;IL1R1;IRAK1;REL;IRAK3;TAB1;PIK3R1
WP2637,"Structural Pathway of Interleukin 1 (IL-1)",WikiPathways,TAB3;ELK1;MKNK1;EIF4E;MAPK9;MAP2K2;RPS6KA5;MAP2K1;MAP2K7;MAP3K8;MAP3K7;IL1A;MAP2K6;MAPK3;NFKB1;MYC;MAPK1;MAPK8;MAPK14;RELA;MAPKAPK2;MKNK2;TOLLIP;TANK;IL1RAP;IRAK2;IL1R1;IRAK1;TAB1;FOS
WP3858,"Toll-like Receptor Signaling",WikiPathways,TLR5;RELB;TIRAP;RELA;TOLLIP;IRAK1;REL;TBK1;TLR3;TLR4;TLR1;TLR2;NFKB1;MAPK1
WP75,"Toll-like Receptor Signaling Pathway",WikiPathways,"JUN;CCL3;CCL5;CCL4;RIPK1;MAP3K7;MAP3K8;AKT1;AKT2;CD14;AKT3;SPP1;NFKB1;TLR5;TIRAP;MAPK14;RELA;TOLLIP;CASP8;TNF;FADD;CXCL8;MAPK9;MAP2K2;MAPK13;IL12A;MAP2K1;MAP2K7;MAP2K6;IFNA1 ;IFNA16;MAPK3;RAC1;MAPK1;MAPK8;IFNAR1;IFNAR2;IL1B;IRAK1;TBK1;PIK3CA;PIK3CB;PIK3CD;TLR3;TLR4;TAB1;TLR1;FOS;TLR2;PIK3CG;PIK3R1;IL6"