pathway_id,pathway_term,pathway_source,proteins
h_IL12Pathway,"IL12 and Stat4 Dependent Signaling Pathway in Th1 Development",BioCarta,MAPK14;IL12A;IL12RB1;IL18;JAK2;JUN;MAPK8;MAP2K6;IL18R1;ETV5
h_nktPathway,"Selective expression of chemokine receptors during T-cell polarization",BioCarta,CD4;CD28;CD40LG;IFNGR1;IFNGR2;IL4R;IL12A;IL12RB1;TGFB1;TGFB2;CXCR4;IL18R1;CCL3;CCL4
h_th1th2Pathway,"Th1/Th2 Differentiation",BioCarta,CD28;IFNGR1;IFNGR2;CD40LG;HLA-DRA;HLA-DRB1;IL4R;IL12A;IL12RB1;IL18;IL18R1
hsa04060,"Cytokine-cytokine receptor interaction",KEGG,"TNFSF13B;CSF1R;CSF3R;CTF1;EGFR;EPOR;FLT4;CLCF1;AMH;GH1;AMHR2;GHR;TNFRSF21;CXCL1;CXCL2;HGF;IFNE;IFNA1 ;IFNA16;IFNAR1;IFNAR2;IFNGR1;IFNGR2;FAS;IL1A;IL1B;IL1R1;IL1RAP;IL4R;IL5RA;IL6;IL6R;IL6ST;IL7R;CXCL8;CXCR2;IL9R;IL10;IL10RB;IL11;IL12A;IL12RB1;IL18;INHBA;INHBB;INHBC;KIT;LEP;LEPR;LIF;LIFR;LTBR;MET;KITLG;NGFR;TNFRSF11B;TNFRSF12A;PDGFA;PDGFB;PDGFRA;PDGFRB;PF4;PPBP;TNFRSF19;IL17RB;PDGFC;PRL;PRLR;CXCL16;CCL2;CCL3;CCL4;CCL5;CCL8;CCL20;CXCL6;CXCL5;CXCL12;BMP2;BMPR1A;BMPR2;TGFB1;TGFB2;TGFBR1;TGFBR2;TNF;TNFRSF1B;TNFSF4;VEGFA;VEGFB;VEGFC;IL1R2;CXCR4;GDF5;TNFSF11;TNFRSF25;TNFSF13;TNFSF10;TNFRSF11A;TNFRSF10C;IL18R1;ACVR1;ACVR1B;OSMR;ACVR2A;ACVR2B;CD27;TNFRSF8;CXCL14;CD40LG"
hsa04668,"TNF signaling pathway",KEGG,AKT3;TAB1;CEBPB;MAP3K8;CREB1;MAPK14;JAG1;EDN1;AKT1;AKT2;FOS;TAB3;CXCL1;CXCL2;BIRC3;ICAM1;FAS;IL1B;IL6;JUN;JUNB;LIF;MAP3K5;MMP9;MMP14;ATF4;NFKB1;PIK3CA;PIK3CB;PIK3CD;PIK3R1;MAPK1;MAPK3;MAPK8;MAPK9;MAPK13;MAP2K1;MAP2K6;MAP2K7;PTGS2;RELA;BCL3;CCL2;CCL5;CCL20;CXCL5;SELE;MAP3K7;TNF;TNFAIP3;TNFRSF1B;TRAF1;VCAM1;VEGFC;ITCH;CASP8;TRADD;RIPK1;FADD;IL18R1;CFLAR;SOCS3;CREB3L1;RPS6KA5;CREB5
hsa05321,"Inflammatory bowel disease (IBD)",KEGG,HLA-DMA;HLA-DMB;HLA-DOB;HLA-DPA1;HLA-DQA1;HLA-DQA2;HLA-DQB1;HLA-DRA;HLA-DRB1;HLA-DRB3;HLA-DRB4;HLA-DRB5;IFNGR1;IFNGR2;IL1A;IL1B;IL4R;IL6;IL10;IL12A;IL12RB1;IL18;JUN;SMAD2;SMAD3;MAF;NFATC1;NFKB1;FOXP3;RELA;RORA;STAT3;TGFB1;TGFB2;TLR2;TLR4;TLR5;TNF;IL18R1