pathway_id,pathway_term,pathway_source,proteins
h_pparaPathway,"Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha)",BioCarta,CREBBP;DUSP1;EP300;HSPA1A;HSP90AA1;JUN;LPL;MYC;PIK3CA;PIK3CG;PIK3R1;PPARA;PRKAR1A;PRKAR2A;PRKAR2B;PRKCA;PRKCB;MAPK1;MAPK3;RB1;RELA;STAT5A;STAT5B;TNF;NCOA1;NCOR1;NCOR2;PPARGC1A;ACOX1;APOA1;APOA2;DUT;HSD17B4;PDGFA;NRIP1;NR0B2;SRA1;NR1H3;CITED2
h_ppargPathway,"Role of PPAR-gamma Coactivators in Obesity and Thermogenesis",BioCarta,CREBBP;EP300;LPL;PPARG;NCOA1;NCOA2;PPARGC1A
h_rarrxrPathway,"Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells",BioCarta,POLR2A;NCOA3;NCOA1;HDAC3;KAT2B;NCOA2;GTF2A1;GTF2B;GTF2F1;NCOR2
h_vdrPathway,"Control of Gene Expression by Vitamin D Receptor",BioCarta,CREBBP;HDAC1;ACTL6A;EP300;PRMT1;SMARCA4;SMARCC1;SMARCC2;SMARCD1;TSC2;VDR;NCOA3;ARID1A;NCOA1;KAT2B;BAZ1B;NCOR1;CHAF1A;CARM1;NCOA2;SUPT16H
hsa04919,"Thyroid hormone signaling pathway",KEGG,AKT3;MED16;NCOA2;SLC16A10;CREBBP;CTNNB1;DIO2;RCAN1;EP300;AKT1;AKT2;ESR1;FOXO1;PLCB1;GATA4;MED4;GSK3B;HDAC1;HDAC2;HIF1A;ITGAV;ITGB3;KRAS;MDM2;MYC;ATP1A2;ATP1B1;ATP1B3;NOTCH1;NOTCH2;ATP2A2;NRAS;PFKFB2;PIK3CA;PIK3CB;PIK3CD;PIK3R1;PLCD1;PLCG2;PLN;PRKACA;PRKCA;PRKCB;MAPK1;MAPK3;MAP2K1;MAP2K2;BAD;RAF1;ACTB;RHEB;RXRB;SLC2A1;BMP4;THRA;ACTG1;TP53;TSC2;NCOA3;CASP9;NCOA1;HDAC3;KAT2B;MED30;MED14;MED17;NCOR1;TBC1D4;MED12
hsa05224,"Breast cancer",KEGG,AKT3;CDK4;CDK6;CDKN1A;CSNK1A1;CTNNB1;JAG1;E2F1;E2F2;EGFR;ERBB2;AKT1;AKT2;ESR1;ESR2;FGF2;FGF7;FGF9;FGF11;FGF12;FGF13;FGF14;FGFR1;FLT4;HEY1;FOS;SHC2;HEYL;GRB2;GSK3B;APC;HES1;IGF1;IGF1R;JUN;KIT;KRAS;LRP6;LRP5;MYC;NOTCH1;NOTCH2;NRAS;PGR;PIK3CA;PIK3CB;PIK3CD;PIK3R1;DLL4;MAPK1;MAPK3;MAP2K1;MAP2K2;PTEN;RAF1;RB1;SOS1;SOS2;BRCA1;BRCA2;TCF7L2;TP53;WNT2;WNT3;WNT5A;WNT6;WNT2B;WNT5B;NCOA3;AXIN1;FZD4;FZD6;FZD7;FZD8;TCF7L1;TNFSF11;NCOA1;FGF18;FGF19
WP138,"Androgen receptor signaling pathway",WikiPathways,JUN;STAT3;RACK1;FKBP4;RHOB;RHOA;CREBBP;PSMC3IP;ZMIZ1;NCOR2;PTK2;NCOR1;BRCA1;RAD9A;MDM2;RB1;CREB1;AES;AKT1;SMAD3;SMAD4;KDM1A;RAC1;RNF14;ETV5;RUNX2;EP300;EGFR;NCOA4;RELA;GSK3B;FLNA;STUB1;UBE2I;NCOA3;CDKN1A;CTNNB1;LIMK2;DSTN;TGFB1I1;NCOA1;RNF6;AR;ROCK2;CALR;PTEN;KAT2B;FOXO1;CAV1;PRDX1;NCOA2;PLPP1;CARM1;KLK3;NR0B2;HDAC1;PIK3R1;PATZ1;CDC42
WP2034,"Leptin signaling pathway",WikiPathways,PTPN11;STAT3;RAF1;ELK1;ESR1;SOCS2;RHOA;EIF4E;EIF4EBP1;BAD;KHDRBS1;ERBB2;PTK2;NOS3;MAP2K2;MAP2K1;BAX;CREB1;JAK1;AKT1;JAK2;LEPR;GRB2;LEP;ACACB;SH2B1;MAPK3;STAT5B;NFKB1;RAC1;SOS1;RPS6;MAPK1;RPS6KA1;PDE3B;MAPK8;MAPK14;RELA;GSK3B;KPNA4;NCOA1;PRKAA2;IL1B;SOCS3;IL1RN;ROCK2;REL;PTEN;FOXO1;PLCG2;IRS1;FYN;PIK3R1;CDC42
WP236,Adipogenesis,WikiPathways,MEF2C;TWIST1;MEF2D;STAT3;MEF2A;PPARGC1A;STAT2;KLF6;CISD1;IGF1;GADD45B;NAMPT;PTGIS;UCP1;TRIB3;RORA;HIF1A;CREB1;CYP26A1;STAT5B;STAT5A;RBL1;LPL;PRLR;SOCS1;GATA4;KLF15;TGFB1;NCOA1;GTF3A;GADD45A;PLIN1;DDIT3;ID3;SOCS3;WNT5B;FOXO1;ADIPOQ;IRS2;SERPINE1;NCOA2;AGT;E2F1;NR2F1;BMP1;TNF;AHR;SLC2A4;LPIN1;LMNA;CEBPB;HNF1A;SCD;CEBPD;INS;NR1H3;MBNL1;NCOR2;NCOR1;PLIN2;NR3C1;RB1;DLK1;LEP;SMAD3;CYP26B1;EGR2;PCK2;PCK1;EPAS1;LIPE;CDKN1A;NRIP1;CTNNB1;PPARA;IL6ST;KLF7;BMP3;BMP4;HMGA1;BMP2;PNPLA3;PPARG;PPARD;MIF;RETN;FAS;GH1;LIF;LIFR;IRS1;SREBF1;IRS4;SFRP4;IL6
WP2873,"Aryl Hydrocarbon Receptor Pathway",WikiPathways,JUN;HES1;EGFR;EP300;TNF;CDKN1B;AHR;JUND;JUNB;NQO1;NCOA1;TGFB1;AIP;IGFBP1;HSP90AA1;IL1B;CYP1A1;SLC7A5;CYP1B1;POLK;AHRR;IL12A;BAX;CDC37;CES3;MGST1;ARNT;PTGES3
WP2875,"Constitutive Androstane Receptor Pathway",WikiPathways,SMC1A;PPARGC1A;CYP3A5;SULT2A1;CYP3A4;CYP2A6;NCOA1;HSP90AA1;FOXO1;NCOA2;PPP2R4;DNAJC7;CYP2C9;CYP2B6
WP364,"IL-6 signaling pathway",WikiPathways,PTPN11;STAT3;GSK3B;JUNB;NCOA1;CREBBP;IRF1;BAD;SOCS3;PRKCD;IL6R;NLK;MAP2K2;IL6ST;MAP2K1;CRP;VAV1;MAP3K7;JAK1;AKT1;JAK2;AGT;GAB1;GRB2;HDAC1;MAPK3;TIMP1;IL6;PIK3R1;RAC1;SOS1;MAPK1