pathway_id,pathway_term,pathway_source,proteins
h_appPathway,"Generation of amyloid b-peptide by PS1",BioCarta,APP;PSEN1;ADAM10
h_erbB4pathway,"g-Secretase mediated ErbB4 Signaling Pathway ",BioCarta,ERBB4;PRKCA;PRKCB;PSEN1;ADAM17
h_HivnefPathway,"HIV-I Nef: negative effector of Fas and TNF",BioCarta,ACTG1;PARP1;BIRC3;XIAP;FAS;ARHGDIB;BCL2;BID;CASP6;CASP8;CASP9;CDK11B;DFFA;LMNA;LMNB1;MDM2;MAP3K5;NFKB1;PAK2;PRKCD;PRKDC;MAPK8;MAP2K7;PSEN1;PSEN2;PTK2;RASA1;RB1;RELA;TNF;TNFRSF1B;TRAF1;TRADD;RIPK1;CRADD;FADD;CFLAR;CEP104;CYCS;LMNB2;CDK11A
h_notchpathway,"Proteolysis and Signaling Pathway of Notch ",BioCarta,NOTCH1;PSEN1;ADAM17;FURIN
h_ps1Pathway,"Presenilin action in Notch and Wnt signaling",BioCarta,APC;CTNNB1;GSK3B;HNF1A;AXIN1;BTRC;NOTCH1;PSEN1;ADAM17
hsa04310,"Wnt signaling pathway",KEGG,WIF1;CREBBP;PRICKLE1;CSNK1A1;CSNK1E;CTBP2;CTNNB1;EP300;GPC4;DKK1;DAAM1;PLCB1;BAMBI;CACYBP;DKK2;INVS;GSK3B;APC;JUN;RHOA;LRP6;LRP5;SMAD3;SMAD4;MYC;NFATC1;NFATC2;NFATC4;SOST;NLK;SERPINF1;PPARD;PPP3CA;PPP3R2;PRKACA;PRKCA;PRKCB;MAPK8;MAPK9;PSEN1;CHD8;RAC1;RAC2;RAC3;SFRP1;SFRP4;SFRP5;SOX17;SIAH1;SKP1;MAP3K7;TBL1X;TCF7L2;TP53;WNT2;WNT3;WNT5A;WNT6;WNT2B;TBL1XR1;FOSL1;WNT5B;CAMK2D;AXIN1;FZD4;FZD6;FZD7;FZD8;TCF7L1;RUVBL1;CCND2;BTRC;CCND3;ROCK2;RBX1
hsa04330,"Notch signaling pathway",KEGG,CREBBP;CTBP2;PTCRA;JAG1;EP300;HDAC1;HDAC2;HES1;NOTCH1;NOTCH2;APH1A;DLL4;MAML3;PSEN1;PSEN2;RFNG;ADAM17;APH1B;MAML2;NUMB;KAT2B;NCOR2
hsa04722,"Neurotrophin signaling pathway",KEGG,AKT3;SH2B3;ZNF274;FRS2;IRAK3;CRKL;MAPK14;AKT1;AKT2;FOXO3;GAB1;SHC2;SH2B1;GRB2;RAPGEF1;GSK3B;IRAK1;IRAK2;IRS1;JUN;KRAS;RHOA;ARHGDIA;ARHGDIB;MAP3K5;ATF4;NFKB1;NGF;NGFR;NRAS;NTRK1;NTRK2;PIK3CA;PIK3CB;PIK3CD;PIK3R1;PLCG2;PRKCD;MAPK1;MAPK3;MAPK7;MAPK8;MAPK9;MAPK13;MAP2K1;MAP2K2;MAP2K5;MAP2K7;PSEN1;PSEN2;BAD;KIDINS220;PTPN11;BAX;RAC1;RAF1;RAP1A;BCL2;RELA;RPS6KA1;RPS6KA2;BDNF;SOS1;SOS2;TP53;YWHAE;CALM2;CALM3;CAMK2D;RIPK2;CALML4;RPS6KA5;MAPKAPK2;CDC42
hsa05010,"Alzheimer's disease",KEGG,ADAM10;CDK5;ATP5H;UQCR11;NDUFA11;COX5B;COX6A1;COX6B1;COX6C;COX7B;COX7C;CYC1;COX7B2;ERN1;ATF6;PLCB1;GAPDH;UQCRQ;GNAQ;GRIN2A;GSK3B;UQCR10;HSD17B10;APBB1;IDE;APOE;APP;FAS;IL1B;ITPR1;ITPR2;ITPR3;LPL;MAPT;MME;UQCRHL;NDUFA1;NDUFA2;NDUFA4;NDUFA5;NDUFA7;NDUFA10;NDUFAB1;NDUFB4;NDUFB6;NDUFB7;NDUFB8;NDUFB10;NDUFS1;NDUFS2;NDUFS4;NDUFS6;NDUFS8;NDUFV2;NDUFV3;ATP2A2;ATP5C1;NDUFA13;APH1A;ATP5D;ATP5E;ATP5G2;ATP5G3;ATP5J;ATP5O;CYCS;NDUFB11;PPP3CA;PPP3R2;MAPK1;MAPK3;PSEN1;PSEN2;RTN4;BAD;RYR3;BID;SDHA;SDHB;SDHC;SNCA;ADAM17;TNF;UQCRB;UQCRC1;UQCRC2;UQCRFS1;UQCRH;CACNA1C;CALM2;CALM3;APH1B;CASP8;CASP9;FADD;NAE1;CALML4;COX5A
WP2059,"Alzheimers Disease",WikiPathways,CALM2;NAE1;PPP3R2;ATP2A2;ADAM17;MME;ITPR3;APOE;MIR21;LPL;HSD17B10;APH1A;GAPDH;ATF6;IDE;ADAM10;ERN1;GNAQ;APBB1;CYCS;MIR132;CALM3;CASP9;CASP8;PLCB1;TNF;RYR3;FADD;BAD;GRIN2A;BID;CACNA1C;MAPK3;MAPK1;ITPR1;ITPR2;PSEN2;GSK3B;PSEN1;IL1B;SNCA;MAPT;TP53;PPP3CA;APP;CDK5;FAS;CHP1
WP268,"Notch Signaling Pathway",WikiPathways,NOTCH2;HES1;NOTCH1;NUMB;PSEN2;PSEN1;PTCRA;APH1A;ADAM17;RFNG;APH1B;CREBBP;CTBP2;NCOR2;DLL4;KAT2B;JAG1;MAML3;INPP5K;HDAC1;HDAC2
WP3845,"Canonical  and Non-canonical Notch signaling",WikiPathways,NOTCH2;HES1;DNER;NOTCH1;PSEN2;PSEN1;HEY1;RRAS;ADAM10;MFAP2;MAML2;DLL4;JAG1;DLK1;MAML3
WP61,"Notch Signaling Pathway",WikiPathways,STAT3;NOTCH2;HES1;NOTCH1;HEY1;ADAM17;HES6;NCOR2;NCOR1;MAML2;DLL4;HIF1A;AKT1;JAK2;RING1;NFKB1;MYC;EP300;GSK3B;PSEN2;NUMB;PSEN1;CDKN1A;PTCRA;APH1A;SKP1;SPEN;FHL1;APH1B;TLE1;MAPT;JAG1;MAML3;HDAC1;HDAC2;ITCH;PIK3R1