pathway_id,pathway_term,pathway_source,proteins
h_IL12Pathway,"IL12 and Stat4 Dependent Signaling Pathway in Th1 Development",BioCarta,MAPK14;IL12A;IL12RB1;IL18;JAK2;JUN;MAPK8;MAP2K6;IL18R1;ETV5
h_nktPathway,"Selective expression of chemokine receptors during T-cell polarization",BioCarta,CD4;CD28;CD40LG;IFNGR1;IFNGR2;IL4R;IL12A;IL12RB1;TGFB1;TGFB2;CXCR4;IL18R1;CCL3;CCL4
h_no2il12Pathway,"NO2-dependent IL 12 Pathway in NK cells",BioCarta,CD4;IL12A;IL12RB1;JAK2
h_th1th2Pathway,"Th1/Th2 Differentiation",BioCarta,CD28;IFNGR1;IFNGR2;CD40LG;HLA-DRA;HLA-DRB1;IL4R;IL12A;IL12RB1;IL18;IL18R1
hsa04060,"Cytokine-cytokine receptor interaction",KEGG,"TNFSF13B;CSF1R;CSF3R;CTF1;EGFR;EPOR;FLT4;CLCF1;AMH;GH1;AMHR2;GHR;TNFRSF21;CXCL1;CXCL2;HGF;IFNE;IFNA1 ;IFNA16;IFNAR1;IFNAR2;IFNGR1;IFNGR2;FAS;IL1A;IL1B;IL1R1;IL1RAP;IL4R;IL5RA;IL6;IL6R;IL6ST;IL7R;CXCL8;CXCR2;IL9R;IL10;IL10RB;IL11;IL12A;IL12RB1;IL18;INHBA;INHBB;INHBC;KIT;LEP;LEPR;LIF;LIFR;LTBR;MET;KITLG;NGFR;TNFRSF11B;TNFRSF12A;PDGFA;PDGFB;PDGFRA;PDGFRB;PF4;PPBP;TNFRSF19;IL17RB;PDGFC;PRL;PRLR;CXCL16;CCL2;CCL3;CCL4;CCL5;CCL8;CCL20;CXCL6;CXCL5;CXCL12;BMP2;BMPR1A;BMPR2;TGFB1;TGFB2;TGFBR1;TGFBR2;TNF;TNFRSF1B;TNFSF4;VEGFA;VEGFB;VEGFC;IL1R2;CXCR4;GDF5;TNFSF11;TNFRSF25;TNFSF13;TNFSF10;TNFRSF11A;TNFRSF10C;IL18R1;ACVR1;ACVR1B;OSMR;ACVR2A;ACVR2B;CD27;TNFRSF8;CXCL14;CD40LG"
hsa04630,"Jak-STAT signaling pathway",KEGG,"AKT3;STAM2;CDKN1A;IRF9;CREBBP;CSF3R;CTF1;EP300;EPOR;AKT1;AKT2;FHL1;GH1;GHR;GRB2;AOX1;IFNE;IFNA1 ;IFNA16;IFNAR1;IFNAR2;IFNGR1;IFNGR2;IL4R;IL5RA;IL6;IL6R;IL6ST;IL7R;IL9R;IL10;IL10RB;IL11;IL12A;IL12RB1;JAK1;JAK2;JAK3;LEP;LEPR;LIF;LIFR;MCL1;MYC;PIK3CA;PIK3CB;PIK3CD;PIK3R1;PRL;PRLR;PTPN2;PTPN11;RAF1;BCL2;SOS1;SOS2;STAT2;STAT3;STAT5A;STAT5B;STAM;SOCS1;SOCS2;CCND2;CCND3;SOCS3;OSMR;SOCS6;SOCS5"
hsa04658,"Th1 and Th2 cell differentiation",KEGG,MAPK14;JAG1;FOS;HLA-DMA;HLA-DMB;HLA-DOB;HLA-DPA1;HLA-DQA1;HLA-DQA2;HLA-DQB1;HLA-DRA;HLA-DRB1;HLA-DRB3;HLA-DRB4;HLA-DRB5;IFNGR1;IFNGR2;IL4R;IL12A;IL12RB1;JAK1;JAK2;JAK3;JUN;MAF;NFATC1;NFATC2;NFKB1;NOTCH1;NOTCH2;DLL4;PPP3CA;PPP3R2;MAML3;PRKCQ;MAPK1;MAPK3;MAPK8;MAPK9;MAPK13;RELA;STAT5A;STAT5B;MAML2;RUNX3;CD4
hsa04659,"Th17 cell differentiation",KEGG,MAPK14;AHR;FOS;HIF1A;HLA-DMA;HLA-DMB;HLA-DOB;HLA-DPA1;HLA-DQA1;HLA-DQA2;HLA-DQB1;HLA-DRA;HLA-DRB1;HLA-DRB3;HLA-DRB4;HLA-DRB5;HSP90AA1;HSP90AB1;IFNGR1;IFNGR2;IL1B;IL1R1;IL1RAP;IL4R;IL6;IL6R;IL6ST;IL12RB1;JAK1;JAK2;JAK3;JUN;SMAD2;SMAD3;SMAD4;NFATC1;NFATC2;NFKB1;FOXP3;PPP3CA;PPP3R2;PRKCQ;MAPK1;MAPK3;MAPK8;MAPK9;MAPK13;RELA;RORA;RXRB;STAT3;STAT5A;STAT5B;TGFB1;TGFBR1;TGFBR2;RUNX1;CD4
hsa05321,"Inflammatory bowel disease (IBD)",KEGG,HLA-DMA;HLA-DMB;HLA-DOB;HLA-DPA1;HLA-DQA1;HLA-DQA2;HLA-DQB1;HLA-DRA;HLA-DRB1;HLA-DRB3;HLA-DRB4;HLA-DRB5;IFNGR1;IFNGR2;IL1A;IL1B;IL4R;IL6;IL10;IL12A;IL12RB1;IL18;JUN;SMAD2;SMAD3;MAF;NFATC1;NFKB1;FOXP3;RELA;RORA;STAT3;TGFB1;TGFB2;TLR2;TLR4;TLR5;TNF;IL18R1