Pathway ID | hsa05418 |
Pathway Term | Fluid shear stress and atherosclerosis |
Pathway Source | KEGG |
Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
---|---|---|---|---|
AKT3 |
v-akt murine thymoma viral oncogene homolog 3 |
10000 |
Q9Y243 |
chr1: 243,488,233-243,851,079 |
CDH5 |
cadherin 5, type 2 (vascular endothelium) |
1003 |
P33151 |
chr16: 66,366,622-66,404,786 |
KLF2 |
Kruppel-like factor 2 |
10365 |
Q9Y5W3 |
chr19: 16,324,817-16,327,874 |
GSTO2 |
glutathione S-transferase omega 2 |
119391 |
Q9H4Y5 |
chr10: 104,268,873-104,304,945 |
MAPK14 |
mitogen-activated protein kinase 14 |
1432 |
Q16539 |
chr6: 36,027,677-36,111,236 |
CTNNB1 |
catenin beta 1 |
1499 |
P35222 |
chr3: 41,194,837-41,260,096 |
CTSL |
cathepsin L |
1514 |
P07711 |
chr9: 87,725,519-87,731,393 |
NQO1 |
NAD(P)H dehydrogenase, quinone 1 |
1728 |
P15559 |
chr16: 69,706,996-69,726,951 |
DUSP1 |
dual specificity phosphatase 1 |
1843 |
P28562 |
chr5: 172,768,090-172,771,195 |
EDN1 |
endothelin 1 |
1906 |
P05305 |
chr6: 12,290,363-12,297,194 |
AKT1 |
v-akt murine thymoma viral oncogene homolog 1 |
207 |
P31749 |
chr14: 104,769,349-104,795,751 |
AKT2 |
v-akt murine thymoma viral oncogene homolog 2 |
208 |
P31751 |
chr19: 40,230,317-40,285,536 |
FOS |
FBJ murine osteosarcoma viral oncogene homolog |
2353 |
P01100 |
chr14: 75,278,774-75,282,230 |
TXN2 |
thioredoxin 2 |
25828 |
Q99757 |
chr22: 36,467,036-36,482,030 |
GPC1 |
glypican 1 |
2817 |
P35052 |
chr2: 240,435,671-240,468,078 |
GSTA1 |
glutathione S-transferase alpha 1 |
2938 |
P08263 |
chr6: 52,791,664-52,803,910 |
GSTA4 |
glutathione S-transferase alpha 4 |
2941 |
O15217 |
chr6: 52,977,948-52,995,378 |
GSTM1 |
glutathione S-transferase mu 1 |
2944 |
P09488 |
chr1: 109,687,814-109,709,039 |
GSTM2 |
glutathione S-transferase mu 2 (muscle) |
2946 |
P28161 |
chr1: 109,668,022-109,709,551 |
GSTM3 |
glutathione S-transferase mu 3 (brain) |
2947 |
P21266 |
chr1: 109,733,932-109,741,038 |
GSTM4 |
glutathione S-transferase mu 4 |
2948 |
Q03013 |
chr1: 109,656,081-109,674,836 |
GSTP1 |
glutathione S-transferase pi 1 |
2950 |
P09211 |
chr11: 67,583,595-67,586,660 |
GSTT1 |
glutathione S-transferase theta 1 |
2952 |
P30711 |
chr22: 24,033,952-24,042,493 |
GSTT2 |
glutathione S-transferase theta 2 (gene/pseudogene) |
2953 |
P0CG29 |
chr22: 23,980,058-23,983,915 |
HMOX1 |
heme oxygenase 1 |
3162 |
P09601 |
chr22: 35,380,361-35,394,214 |
HSP90AA1 |
heat shock protein 90kDa alpha family class A member 1 |
3320 |
P07900 |
chr14: 102,080,738-102,139,699 |
HSP90AB1 |
heat shock protein 90kDa alpha family class B member 1 |
3326 |
P08238 |
chr6: 44,246,166-44,253,888 |
ICAM1 |
intercellular adhesion molecule 1 |
3383 |
P05362 |
chr19: 10,270,835-10,286,615 |
IL1A |
interleukin 1 alpha |
3552 |
P01583 |
chr2: 112,773,915-112,784,590 |
IL1B |
interleukin 1 beta |
3553 |
P01584 |
chr2: 112,829,751-112,836,903 |
IL1R1 |
interleukin 1 receptor, type I |
3554 |
P14778 |
chr2: 102,064,544-102,179,874 |
ITGAV |
integrin subunit alpha V |
3685 |
P06756 |
chr2: 186,590,065-186,680,901 |
ITGB3 |
integrin subunit beta 3 |
3690 |
P05106 |
chr17: 47,253,846-47,311,816 |
JUN |
jun proto-oncogene |
3725 |
P05412 |
chr1: 58,780,788-58,784,327 |
RHOA |
ras homolog family member A |
387 |
P61586 |
chr3: 49,359,145-49,412,998 |
SUMO4 |
small ubiquitin-like modifier 4 |
387082 |
Q6EEV6 |
chr6: 149,400,227-149,401,292 |
MEF2A |
myocyte enhancer factor 2A |
4205 |
Q02078 |
chr15: 99,565,417-99,716,466 |
MEF2C |
myocyte enhancer factor 2C |
4208 |
Q06413 |
chr5: 88,717,117-88,904,257 |
MAP3K5 |
mitogen-activated protein kinase kinase kinase 5 |
4217 |
Q99683 |
chr6: 136,557,047-136,792,518 |
MGST1 |
microsomal glutathione S-transferase 1 |
4257 |
P10620 |
chr12: 16,347,142-16,609,259 |
MGST2 |
microsomal glutathione S-transferase 2 |
4258 |
Q99735 |
chr4: 139,665,768-139,740,745 |
MGST3 |
microsomal glutathione S-transferase 3 |
4259 |
O14880 |
chr1: 165,630,861-165,661,796 |
MMP2 |
matrix metallopeptidase 2 |
4313 |
P08253 |
chr16: 55,389,700-55,506,691 |
MMP9 |
matrix metallopeptidase 9 |
4318 |
P14780 |
chr20: 46,008,908-46,016,561 |
ASS1 |
argininosuccinate synthase 1 |
445 |
P00966 |
chr9: 130,444,929-130,501,274 |
NCF2 |
neutrophil cytosolic factor 2 |
4688 |
P19878 |
chr1: 183,555,563-183,590,876 |
NFKB1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
4790 |
P19838 |
chr4: 102,501,329-102,617,302 |
NOS3 |
nitric oxide synthase 3 |
4846 |
P29474 |
chr7: 150,990,995-151,014,588 |
PDGFA |
platelet-derived growth factor alpha polypeptide |
5154 |
P04085 |
chr7: 497,258-520,296 |
PDGFB |
platelet-derived growth factor beta polypeptide |
5155 |
P01127 |
chr22: 39,223,359-39,244,751 |
PECAM1 |
platelet/endothelial cell adhesion molecule 1 |
5175 |
P16284 |
chr17: 64,319,415-64,413,776 |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
5290 |
P42336 |
chr3: 179,148,114-179,240,093 |
PIK3CB |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
5291 |
P42338 |
chr3: 138,652,699-138,834,938 |
PIK3CD |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
5293 |
O00329 |
chr1: 9,651,732-9,729,114 |
PIK3R1 |
phosphoinositide-3-kinase regulatory subunit 1 |
5295 |
P27986 |
chr5: 68,215,720-68,301,821 |
PLAT |
plasminogen activator, tissue |
5327 |
P00750 |
chr8: 42,175,233-42,207,724 |
PRKAA2 |
protein kinase, AMP-activated, alpha 2 catalytic subunit |
5563 |
P54646 |
chr1: 56,645,322-56,715,335 |
MAPK7 |
mitogen-activated protein kinase 7 |
5598 |
Q13164 |
chr17: 19,377,721-19,383,544 |
MAPK8 |
mitogen-activated protein kinase 8 |
5599 |
P45983 |
chr10: 48,306,639-48,439,360 |
MAPK9 |
mitogen-activated protein kinase 9 |
5601 |
P45984 |
chr5: 180,233,143-180,292,099 |
MAPK13 |
mitogen-activated protein kinase 13 |
5603 |
O15264 |
chr6: 36,127,809-36,144,524 |
MAP2K5 |
mitogen-activated protein kinase kinase 5 |
5607 |
Q13163 |
chr15: 67,542,709-67,807,123 |
MAP2K6 |
mitogen-activated protein kinase kinase 6 |
5608 |
P52564 |
chr17: 69,414,698-69,543,331 |
MAP2K7 |
mitogen-activated protein kinase kinase 7 |
5609 |
O14733 |
chr19: 7,903,843-7,914,478 |
PTK2 |
protein tyrosine kinase 2 |
5747 |
Q05397 |
chr8: 140,657,900-141,002,216 |
RAC1 |
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
5879 |
P63000 |
chr7: 6,374,523-6,403,977 |
RAC2 |
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
5880 |
P15153 |
chr22: 37,225,261-37,244,448 |
RAC3 |
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
5881 |
P60763 |
chr17: 82,031,624-82,034,204 |
TRPV4 |
transient receptor potential cation channel, subfamily V, member 4 |
59341 |
Q9HBA0 |
chr12: 109,783,085-109,833,401 |
BCL2 |
B-cell CLL/lymphoma 2 |
596 |
P10415 |
chr18: 63,123,346-63,320,128 |
RELA |
v-rel avian reticuloendotheliosis viral oncogene homolog A |
5970 |
Q04206 |
chr11: 65,653,596-65,663,094 |
ACTB |
actin, beta |
60 |
P60709 |
chr7: 5,527,151-5,563,784 |
CCL2 |
chemokine (C-C motif) ligand 2 |
6347 |
P13500 |
chr17: 34,255,218-34,257,203 |
SDC1 |
syndecan 1 |
6382 |
P18827 |
chr2: 20,200,797-20,225,433 |
SDC2 |
syndecan 2 |
6383 |
P34741 |
chr8: 96,493,351-96,611,780 |
SDC4 |
syndecan 4 |
6385 |
P31431 |
chr20: 45,325,288-45,348,424 |
SELE |
selectin E |
6401 |
P16581 |
chr1: 169,722,641-169,764,705 |
BMP4 |
bone morphogenetic protein 4 |
652 |
P12644 |
chr14: 53,949,736-53,958,761 |
BMPR1A |
bone morphogenetic protein receptor type IA |
657 |
P36894 |
chr10: 86,756,601-86,932,838 |
BMPR2 |
bone morphogenetic protein receptor type II |
659 |
Q13873 |
chr2: 202,376,936-202,567,751 |
SUMO3 |
small ubiquitin-like modifier 3 |
6612 |
P55854 |
chr21: 44,805,617-44,818,779 |
SUMO2 |
small ubiquitin-like modifier 2 |
6613 |
P61956 |
chr17: 75,165,586-75,182,983 |
MAP3K7 |
mitogen-activated protein kinase kinase kinase 7 |
6885 |
O43318 |
chr6: 90,513,573-90,587,045 |
ACTG1 |
actin gamma 1 |
71 |
P63261 |
chr17: 81,509,971-81,523,847 |
TNF |
tumor necrosis factor |
7124 |
P01375 |
chr6: 31,575,567-31,578,336 |
TP53 |
tumor protein p53 |
7157 |
P04637 |
chr17: 7,661,779-7,687,550 |
HSP90B1 |
heat shock protein 90kDa beta family member 1 |
7184 |
P14625 |
chr12: 103,930,107-103,953,645 |
TXN |
thioredoxin |
7295 |
P10599 |
chr9: 110,243,811-110,256,640 |
VCAM1 |
vascular cell adhesion molecule 1 |
7412 |
P19320 |
chr1: 100,719,742-100,739,045 |
VEGFA |
vascular endothelial growth factor A |
7422 |
P15692 |
chr6: 43,770,184-43,786,487 |
IL1R2 |
interleukin 1 receptor, type II |
7850 |
P27930 |
chr2: 101,991,844-102,028,544 |
CALM2 |
calmodulin 2 |
805 |
P62158 |
chr2: 47,160,082-47,176,601 |
CALM3 |
calmodulin 3 |
808 |
P62158 |
chr14: 90,396,502-90,408,261 |
CAV1 |
caveolin 1 |
857 |
Q03135 |
chr7: 116,524,785-116,561,184 |
CAV2 |
caveolin 2 |
858 |
P51636 |
chr7: 116,287,380-116,508,541 |
SQSTM1 |
sequestosome 1 |
8878 |
Q13501 |
chr5: 179,806,398-179,838,078 |
ACVR1 |
activin A receptor type I |
90 |
Q04771 |
chr2: 157,736,444-157,875,862 |
ARHGEF2 |
Rho/Rac guanine nucleotide exchange factor 2 |
9181 |
Q92974 |
chr1: 155,946,851-156,007,070 |
CALML4 |
calmodulin like 4 |
91860 |
Q96GE6 |
chr15: 68,190,705-68,206,110 |
ACVR2A |
activin A receptor type IIA |
92 |
P27037 |
chr2: 147,844,517-147,930,826 |
ACVR2B |
activin A receptor type IIB |
93 |
Q13705 |
chr3: 38,453,851-38,493,142 |
GSTO1 |
glutathione S-transferase omega 1 |
9446 |
P78417 |
chr10: 104,235,356-104,267,459 |