Pathway Description

Pathway ID hsa05218
Pathway Term Melanoma
Pathway Source KEGG
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

AKT3

v-akt murine thymoma viral oncogene homolog 3

10000

Q9Y243

chr1: 243,488,233-243,851,079

CDK4

cyclin-dependent kinase 4

1019

P11802

chr12: 57,747,727-57,756,013

CDK6

cyclin-dependent kinase 6

1021

Q00534

chr7: 92,604,921-92,836,594

CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

1026

P38936

chr6: 36,676,460-36,687,339

E2F1

E2F transcription factor 1

1869

Q01094

chr20: 33,675,683-33,686,404

E2F2

E2F transcription factor 2

1870

Q14209

chr1: 23,506,430-23,531,220

EGFR

epidermal growth factor receptor

1956

P00533

chr7: 55,019,021-55,211,628

AKT1

v-akt murine thymoma viral oncogene homolog 1

207

P31749

chr14: 104,769,349-104,795,751

AKT2

v-akt murine thymoma viral oncogene homolog 2

208

P31751

chr19: 40,230,317-40,285,536

FGF2

fibroblast growth factor 2 (basic)

2247

P09038

chr4: 122,826,708-122,898,236

FGF7

fibroblast growth factor 7

2252

P21781

chr15: 49,423,096-49,488,775

FGF9

fibroblast growth factor 9

2254

P31371

chr13: 21,671,383-21,704,498

FGF11

fibroblast growth factor 11

2256

Q92914

chr17: 7,438,273-7,444,937

FGF12

fibroblast growth factor 12

2257

P61328

chr3: 192,139,395-192,767,764

FGF13

fibroblast growth factor 13

2258

Q92913

chrX: 138,614,731-139,222,777

FGF14

fibroblast growth factor 14

2259

Q92915

chr13: 101,710,804-102,402,457

FGFR1

fibroblast growth factor receptor 1

2260

P11362

chr8: 38,411,138-38,468,834

HGF

hepatocyte growth factor (hepapoietin A; scatter factor)

3082

P14210

chr7: 81,699,006-81,770,438

IGF1

insulin like growth factor 1

3479

P05019

chr12: 102,395,867-102,480,645

IGF1R

insulin like growth factor 1 receptor

3480

P08069

chr15: 98,648,971-98,964,530

KRAS

Kirsten rat sarcoma viral oncogene homolog

3845

P01116

chr12: 25,204,789-25,250,936

MDM2

MDM2 proto-oncogene, E3 ubiquitin protein ligase

4193

Q00987

chr12: 68,808,176-68,850,686

MET

MET proto-oncogene, receptor tyrosine kinase

4233

P08581

chr7: 116,672,390-116,798,386

MITF

microphthalmia-associated transcription factor

4286

O75030

chr3: 69,739,435-69,968,337

NRAS

neuroblastoma RAS viral (v-ras) oncogene homolog

4893

P01111

chr1: 114,704,469-114,716,894

PDGFA

platelet-derived growth factor alpha polypeptide

5154

P04085

chr7: 497,258-520,296

PDGFB

platelet-derived growth factor beta polypeptide

5155

P01127

chr22: 39,223,359-39,244,751

PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

5156

P16234

chr4: 54,229,097-54,298,247

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

5159

P09619

chr5: 150,113,837-150,155,872

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

5290

P42336

chr3: 179,148,114-179,240,093

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

5291

P42338

chr3: 138,652,699-138,834,938

PIK3CD

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

5293

O00329

chr1: 9,651,732-9,729,114

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

5295

P27986

chr5: 68,215,720-68,301,821

MAPK1

mitogen-activated protein kinase 1

5594

P28482

chr22: 21,754,500-21,867,680

MAPK3

mitogen-activated protein kinase 3

5595

P27361

chr16: 30,114,105-30,123,506

PDGFC

platelet derived growth factor C

56034

Q9NRA1

chr4: 156,760,454-156,971,394

MAP2K1

mitogen-activated protein kinase kinase 1

5604

Q02750

chr15: 66,386,817-66,492,312

MAP2K2

mitogen-activated protein kinase kinase 2

5605

P36507

chr19: 4,090,321-4,124,129

BAD

BCL2 associated agonist of cell death

572

Q92934

chr11: 64,269,830-64,284,704

PTEN

phosphatase and tensin homolog

5728

P60484

chr10: 87,863,113-87,971,930

RAF1

Raf-1 proto-oncogene, serine/threonine kinase

5894

P04049

chr3: 12,583,601-12,664,226

RB1

retinoblastoma 1

5925

P06400

chr13: 48,303,751-48,481,986

TP53

tumor protein p53

7157

P04637

chr17: 7,661,779-7,687,550

PDGFD

platelet derived growth factor D

80310

Q9GZP0

chr11: 103,907,186-104,164,379

FGF18

fibroblast growth factor 18

8817

O76093

chr5: 171,419,656-171,457,623

FGF19

fibroblast growth factor 19

9965

O95750

chr11: 69,698,232-69,704,642