Pathway Description

Pathway ID hsa05206
Pathway Term MicroRNAs in cancer
Pathway Source KEGG
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

BCL2L11

BCL2-like 11 (apoptosis facilitator)

10018

O43521

chr2: 111,119,378-111,168,447

CDK6

cyclin-dependent kinase 6

1021

Q00534

chr7: 92,604,921-92,836,594

SPRY2

sprouty RTK signaling antagonist 2

10253

O43597

chr13: 80,335,976-80,340,951

CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

1026

P38936

chr6: 36,676,460-36,687,339

CDKN1B

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

1027

P46527

chr12: 12,715,058-12,722,371

RASSF1

Ras association (RalGDS/AF-6) domain family member 1

11186

Q9NS23

chr3: 50,329,782-50,340,980

CDCA5

cell division cycle associated 5

113130

Q96FF9

chr11: 65,066,300-65,084,164

CREBBP

CREB binding protein

1387

Q92793

chr16: 3,725,054-3,880,726

CRKL

v-crk avian sarcoma virus CT10 oncogene homolog-like

1399

P46109

chr22: 20,917,426-20,953,749

CYP1B1

cytochrome P450 family 1 subfamily B member 1

1545

Q16678

chr2: 38,066,973-38,109,902

DNMT1

DNA (cytosine-5-)-methyltransferase 1

1786

P26358

chr19: 10,133,345-10,231,286

DNMT3B

DNA (cytosine-5-)-methyltransferase 3 beta

1789

Q9UBC3

chr20: 32,762,385-32,809,356

E2F1

E2F transcription factor 1

1869

Q01094

chr20: 33,675,683-33,686,404

E2F2

E2F transcription factor 2

1870

Q14209

chr1: 23,506,430-23,531,220

EGFR

epidermal growth factor receptor

1956

P00533

chr7: 55,019,021-55,211,628

EP300

E1A binding protein p300

2033

Q09472

chr22: 41,091,786-41,180,079

ERBB2

erb-b2 receptor tyrosine kinase 2

2064

P04626

chr17: 39,687,914-39,730,426

ERBB3

erb-b2 receptor tyrosine kinase 3

2065

P21860

chr12: 56,079,857-56,103,505

EZH2

enhancer of zeste 2 polycomb repressive complex 2 subunit

2146

Q15910

chr7: 148,807,383-148,884,321

DICER1

dicer 1, ribonuclease type III

23405

Q9UPY3

chr14: 95,086,228-95,158,010

ZFPM2

zinc finger protein, FOG family member 2

23414

Q8WW38

chr8: 104,590,733-105,804,532

FOXP1

forkhead box P1

27086

Q9H334

chr3: 70,954,693-71,583,989

PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

27250

Q53EL6

chr10: 110,871,795-110,900,006

GLS

glutaminase

2744

O94925

chr2: 190,880,827-190,965,552

GRB2

growth factor receptor bound protein 2

2885

P62993

chr17: 75,318,076-75,405,709

HDAC1

histone deacetylase 1

3065

Q13547

chr1: 32,292,086-32,333,635

HMOX1

heme oxygenase 1

3162

P09601

chr22: 35,380,361-35,394,214

HOXD10

homeobox D10

3236

P28358

chr2: 176,108,790-176,119,942

APC

adenomatous polyposis coli

324

P25054

chr5: 112,707,498-112,846,239

TNC

tenascin C

3371

P24821

chr9: 115,019,578-115,118,257

IRS1

insulin receptor substrate 1

3667

P35568

chr2: 226,731,317-226,799,759

ITGA5

integrin subunit alpha 5

3678

P08648

chr12: 54,395,261-54,419,460

ITGB3

integrin subunit beta 3

3690

P05106

chr17: 47,253,846-47,311,816

KRAS

Kirsten rat sarcoma viral oncogene homolog

3845

P01116

chr12: 25,204,789-25,250,936

RHOA

ras homolog family member A

387

P61586

chr3: 49,359,145-49,412,998

STMN1

stathmin 1

3925

P16949

chr1: 25,884,181-25,906,991

MIR155

microRNA 155

406947

N/A

chr21: 25,573,980-25,574,044

MIR21

microRNA 21

406991

N/A

chr17: 59,841,266-59,841,337

MIR25

microRNA 25

407014

N/A

chr7: 100,093,560-100,093,643

MARCKS

myristoylated alanine-rich protein kinase C substrate

4082

P29966

chr6: 113,857,362-113,863,471

MCL1

myeloid cell leukemia 1

4170

Q07820

chr1: 150,574,551-150,579,738

MDM2

MDM2 proto-oncogene, E3 ubiquitin protein ligase

4193

Q00987

chr12: 68,808,176-68,850,686

MDM4

MDM4, p53 regulator

4194

O15151

chr1: 204,516,379-204,558,120

MET

MET proto-oncogene, receptor tyrosine kinase

4233

P08581

chr7: 116,672,390-116,798,386

MMP9

matrix metallopeptidase 9

4318

P14780

chr20: 46,008,908-46,016,561

MMP16

matrix metallopeptidase 16

4325

P51512

chr8: 88,032,009-88,328,025

ABCC1

ATP binding cassette subfamily C member 1

4363

P33527

chr16: 15,949,577-16,143,074

MYC

v-myc avian myelocytomatosis viral oncogene homolog

4609

P01106

chr8: 127,735,434-127,741,434

NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

4790

P19838

chr4: 102,501,329-102,617,302

NOTCH1

notch 1

4851

P46531

chr9: 136,494,444-136,545,862

NOTCH2

notch 2

4853

Q04721

chr1: 119,911,553-120,069,626

NRAS

neuroblastoma RAS viral (v-ras) oncogene homolog

4893

P01111

chr1: 114,704,469-114,716,894

PDGFA

platelet-derived growth factor alpha polypeptide

5154

P04085

chr7: 497,258-520,296

PDGFB

platelet-derived growth factor beta polypeptide

5155

P01127

chr22: 39,223,359-39,244,751

PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

5156

P16234

chr4: 54,229,097-54,298,247

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

5159

P09619

chr5: 150,113,837-150,155,872

SERPINB5

serpin peptidase inhibitor, clade B (ovalbumin), member 5

5268

P36952

chr18: 63,476,761-63,505,085

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

5290

P42336

chr3: 179,148,114-179,240,093

PLAU

plasminogen activator, urokinase

5328

P00749

chr10: 73,909,177-73,917,497

PLCG2

phospholipase C gamma 2

5336

P16885

chr16: 81,739,097-81,962,693

DDIT4

DNA damage inducible transcript 4

54541

Q9NX09

chr10: 72,273,920-72,276,036

PRKCA

protein kinase C, alpha

5578

P17252

chr17: 66,302,636-66,810,743

PRKCB

protein kinase C, beta

5579

P05771

chr16: 23,836,001-24,220,611

MAPK1

mitogen-activated protein kinase 1

5594

P28482

chr22: 21,754,500-21,867,680

MAPK7

mitogen-activated protein kinase 7

5598

Q13164

chr17: 19,377,721-19,383,544

MAP2K1

mitogen-activated protein kinase kinase 1

5604

Q02750

chr15: 66,386,817-66,492,312

MAP2K2

mitogen-activated protein kinase kinase 2

5605

P36507

chr19: 4,090,321-4,124,129

PTEN

phosphatase and tensin homolog

5728

P60484

chr10: 87,863,113-87,971,930

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

5743

P35354

chr1: 186,671,791-186,680,427

RAF1

Raf-1 proto-oncogene, serine/threonine kinase

5894

P04049

chr3: 12,583,601-12,664,226

BCL2

B-cell CLL/lymphoma 2

596

P10415

chr18: 63,123,346-63,320,128

RDX

radixin

5962

P35241

chr11: 110,174,880-110,296,722

BCL2L2

BCL2L2-PABPN1 readthrough

599

Q92843

chr14: 23,298,790-23,311,759

BMPR2

bone morphogenetic protein receptor type II

659

Q13873

chr2: 202,376,936-202,567,751

FSCN1

fascin actin-bundling protein 1

6624

Q16658

chr7: 5,592,823-5,606,655

SOS1

SOS Ras/Rac guanine nucleotide exchange factor 1

6654

Q07889

chr2: 38,981,396-39,124,345

SOS2

SOS Ras/Rho guanine nucleotide exchange factor 2

6655

Q07890

chr14: 50,117,120-50,231,558

SOX4

SRY-box 4

6659

Q06945

chr6: 21,592,768-21,598,619

BRCA1

breast cancer 1

672

P38398

chr17: 43,044,295-43,170,245

STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

6774

P40763

chr17: 42,313,324-42,388,568

ZEB1

zinc finger E-box binding homeobox 1

6935

P37275

chr10: 31,318,495-31,529,814

TGFB2

transforming growth factor beta 2

7042

P61812

chr1: 218,346,235-218,444,619

THBS1

thrombospondin 1

7057

P07996

chr15: 39,581,079-39,599,466

TIMP3

TIMP metallopeptidase inhibitor 3

7078

P35625

chr22: 32,801,701-32,863,043

TNR

tenascin R

7143

Q92752

chr1: 175,315,194-175,743,770

TNXB

tenascin XB

7148

P22105

chr6: 32,041,154-32,115,334

TP53

tumor protein p53

7157

P04637

chr17: 7,661,779-7,687,550

TPM1

tropomyosin 1 (alpha)

7168

P09493

chr15: 63,042,632-63,071,915

UBE2I

ubiquitin conjugating enzyme E2I

7329

P63279

chr16: 1,308,880-1,327,018

VEGFA

vascular endothelial growth factor A

7422

P15692

chr6: 43,770,184-43,786,487

EZR

ezrin

7430

P15311

chr6: 158,765,741-158,819,412

VIM

vimentin

7431

P08670

chr10: 17,228,259-17,237,593

WNT3

wingless-type MMTV integration site family member 3

7473

P56703

chr17: 46,762,506-46,833,154

HMGA2

high mobility group AT-hook 2

8091

P52926

chr12: 65,824,131-65,966,295

RECK

reversion-inducing-cysteine-rich protein with kazal motifs

8434

O95980

chr9: 36,036,433-36,124,451

SOCS1

suppressor of cytokine signaling 1

8651

O15524

chr16: 11,254,405-11,256,179

IRS2

insulin receptor substrate 2

8660

Q9Y4H2

chr13: 109,752,698-109,786,568

CCND2

cyclin D2

894

P30279

chr12: 4,273,772-4,305,350

CCNG1

cyclin G1

900

P51959

chr5: 163,437,569-163,446,151

CCNE2

cyclin E2

9134

O96020

chr8: 94,879,770-94,896,678

RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

9252

O75582

chr14: 90,847,862-91,060,636

KIF23

kinesin family member 23

9493

Q02241

chr15: 69,414,246-69,448,427

CD44

CD44 molecule (Indian blood group)

960

P16070

chr11: 35,138,870-35,232,402

HDAC4

histone deacetylase 4

9759

P56524

chr2: 239,048,168-239,401,654

ZEB2

zinc finger E-box binding homeobox 2

9839

O60315

chr2: 144,364,364-144,524,583

CDC25A

cell division cycle 25A

993

P30304

chr3: 48,157,146-48,188,402

CDC25B

cell division cycle 25B

994

P30305

chr20: 3,786,772-3,806,121

CDC25C

cell division cycle 25C

995

P30307

chr5: 138,285,265-138,338,355