Pathway Description

Pathway ID hsa05166
Pathway Term HTLV-I infection
Pathway Source KEGG
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

AKT3

v-akt murine thymoma viral oncogene homolog 3

10000

Q9Y243

chr1: 243,488,233-243,851,079

CDK4

cyclin-dependent kinase 4

1019

P11802

chr12: 57,747,727-57,756,013

CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

1026

P38936

chr6: 36,676,460-36,687,339

CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

1030

P42772

chr9: 22,002,903-22,009,363

CDKN2C

cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)

1031

P42773

chr1: 50,960,745-50,974,633

ANAPC10

anaphase promoting complex subunit 10

10393

Q9UM13

chr4: 144,831,908-145,098,541

POLD3

polymerase (DNA-directed), delta 3, accessory subunit

10714

Q15054

chr11: 74,493,851-74,669,117

ADCY3

adenylate cyclase 3

109

O60266

chr2: 24,819,169-24,919,839

CHEK1

checkpoint kinase 1

1111

O14757

chr11: 125,625,136-125,676,255

ADCY7

adenylate cyclase 7

113

P51828

chr16: 50,246,137-50,318,135

ADCY9

adenylate cyclase 9

115

O60503

chr16: 3,953,387-4,116,185

CREB1

cAMP responsive element binding protein 1

1385

P16220

chr2: 207,529,737-207,603,431

CREBBP

CREB binding protein

1387

Q92793

chr16: 3,725,054-3,880,726

CREM

cAMP responsive element modulator

1390

Q03060

chr10: 35,126,791-35,212,958

CTNNB1

catenin beta 1

1499

P35222

chr3: 41,194,837-41,260,096

DLG1

discs, large homolog 1 (Drosophila)

1739

Q12959

chr3: 197,042,560-197,299,300

E2F1

E2F transcription factor 1

1869

Q01094

chr20: 33,675,683-33,686,404

E2F2

E2F transcription factor 2

1870

Q14209

chr1: 23,506,430-23,531,220

EGR1

early growth response 1

1958

P18146

chr5: 138,465,490-138,469,315

EGR2

early growth response 2

1959

P11161

chr10: 62,811,996-62,919,900

ELK1

ELK1, member of ETS oncogene family

2002

P19419

chrX: 47,635,521-47,650,604

EP300

E1A binding protein p300

2033

Q09472

chr22: 41,091,786-41,180,079

AKT1

v-akt murine thymoma viral oncogene homolog 1

207

P31749

chr14: 104,769,349-104,795,751

AKT2

v-akt murine thymoma viral oncogene homolog 2

208

P31751

chr19: 40,230,317-40,285,536

ETS1

v-ets avian erythroblastosis virus E26 oncogene homolog 1

2113

P14921

chr11: 128,458,761-128,587,558

ETS2

v-ets avian erythroblastosis virus E26 oncogene homolog 2

2114

P15036

chr21: 38,805,307-38,824,955

FDPS

farnesyl diphosphate synthase

2224

P14324

chr1: 155,308,748-155,320,666

RRAS2

related RAS viral (r-ras) oncogene homolog 2

22800

P62070

chr11: 14,277,926-14,364,506

FOS

FBJ murine osteosarcoma viral oncogene homolog

2353

P01100

chr14: 75,278,774-75,282,230

GPS2

G protein pathway suppressor 2

2874

Q13227

chr17: 7,311,324-7,315,564

SLC25A4

solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4

291

P12235

chr4: 185,143,241-185,150,382

SLC25A5

solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5

292

P05141

chrX: 119,468,400-119,471,319

GSK3B

glycogen synthase kinase 3 beta

2932

P49841

chr3: 119,821,323-120,094,417

ANAPC4

anaphase promoting complex subunit 4

29945

Q9UJX5

chr4: 25,377,213-25,418,498

HLA-A

major histocompatibility complex, class I, A

3105

P30443

chr6: 29,941,260-29,945,884

HLA-B

major histocompatibility complex, class I, B

3106

P01889

chr6: 31,269,491-31,357,188

HLA-C

major histocompatibility complex, class I, C

3107

P30499

chr6: 31,268,749-31,272,130

HLA-DMA

major histocompatibility complex, class II, DM alpha

3108

P28067

chr6: 32,948,613-32,969,094

HLA-DMB

major histocompatibility complex, class II, DM beta

3109

P28068

chr6: 32,934,629-32,941,070

HLA-DOB

major histocompatibility complex, class II, DO beta

3112

P13765

chr6: 32,812,763-32,817,048

HLA-DPA1

major histocompatibility complex, class II, DP alpha 1

3113

P20036

chr6: 33,064,569-33,080,775

HLA-DQA1

major histocompatibility complex, class II, DQ alpha 1

3117

P01909

chr6: 32,628,179-32,647,062

HLA-DQA2

major histocompatibility complex, class II, DQ alpha 2

3118

P01906

chr6: 32,741,342-32,747,215

HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

3119

P01920

chr6: 32,659,467-32,668,383

HLA-DRA

major histocompatibility complex, class II, DR alpha

3122

P01903

chr6: 32,439,842-32,445,046

HLA-DRB1

major histocompatibility complex, class II, DR beta 1

3123

P04229

chr6: 32,578,769-32,589,848

HLA-DRB3

major histocompatibility complex, class II, DR beta 3

3125

P79483

chr6: 32,444,128-32,457,245

HLA-DRB4

major histocompatibility complex, class II, DR beta 4

3126

P13762

chr6: 32,542,598-32,557,561

HLA-DRB5

major histocompatibility complex, class II, DR beta 5

3127

Q30154

chr6: 32,517,343-32,530,287

HLA-E

major histocompatibility complex, class I, E

3133

P13747

chr6: 30,489,467-30,494,205

HLA-F

major histocompatibility complex, class I, F

3134

P30511

chr6: 29,722,775-29,738,528

HLA-G

major histocompatibility complex, class I, G

3135

P17693

chr6: 29,826,967-29,831,125

APC

adenomatous polyposis coli

324

P25054

chr5: 112,707,498-112,846,239

XIAP

X-linked inhibitor of apoptosis

331

P98170

chrX: 123,859,724-123,913,979

ICAM1

intercellular adhesion molecule 1

3383

P05362

chr19: 10,270,835-10,286,615

IL1R1

interleukin 1 receptor, type I

3554

P14778

chr2: 102,064,544-102,179,874

IL6

interleukin 6

3569

P05231

chr7: 22,725,884-22,732,002

ITGB2

integrin subunit beta 2

3689

P05107

chr21: 44,885,953-44,931,989

JAK1

Janus kinase 1

3716

P23458

chr1: 64,833,229-64,966,504

JAK3

Janus kinase 3

3718

P52333

chr19: 17,824,780-17,848,071

JUN

jun proto-oncogene

3725

P05412

chr1: 58,780,788-58,784,327

KRAS

Kirsten rat sarcoma viral oncogene homolog

3845

P01116

chr12: 25,204,789-25,250,936

LTBR

lymphotoxin beta receptor

4055

P36941

chr12: 6,375,045-6,391,571

MAD2L1

MAD2 mitotic arrest deficient-like 1 (yeast)

4085

Q13257

chr4: 120,055,608-120,067,074

SMAD2

SMAD family member 2

4087

Q15796

chr18: 47,808,957-47,931,146

SMAD3

SMAD family member 3

4088

P84022

chr15: 67,063,763-67,195,195

SMAD4

SMAD family member 4

4089

Q13485

chr18: 51,028,394-51,085,045

MYBL1

v-myb avian myeloblastosis viral oncogene homolog-like 1

4603

P10243

chr8: 66,562,175-66,614,247

MYBL2

v-myb avian myeloblastosis viral oncogene homolog-like 2

4605

P10244

chr20: 43,667,019-43,716,496

MYC

v-myc avian myelocytomatosis viral oncogene homolog

4609

P01106

chr8: 127,735,434-127,741,434

ATF1

activating transcription factor 1

466

P18846

chr12: 50,763,710-50,821,122

ATF3

activating transcription factor 3

467

P18847

chr1: 212,565,334-212,620,777

ATF4

activating transcription factor 4

468

P18848

chr22: 39,519,695-39,522,685

NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

4772

O95644

chr18: 79,395,856-79,529,325

NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

4773

Q13469

chr20: 51,386,957-51,562,831

NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

4776

Q14934

chr14: 24,365,673-24,379,604

NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

4790

P19838

chr4: 102,501,329-102,617,302

NFYB

nuclear transcription factor Y subunit beta

4801

P25208

chr12: 104,117,077-104,138,289

NRAS

neuroblastoma RAS viral (v-ras) oncogene homolog

4893

P01111

chr1: 114,704,469-114,716,894

PCNA

proliferating cell nuclear antigen

5111

P12004

chr20: 5,114,953-5,126,626

ANAPC5

anaphase promoting complex subunit 5

51433

Q9UJX4

chr12: 121,308,245-121,399,896

PDGFA

platelet-derived growth factor alpha polypeptide

5154

P04085

chr7: 497,258-520,296

PDGFB

platelet-derived growth factor beta polypeptide

5155

P01127

chr22: 39,223,359-39,244,751

PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

5156

P16234

chr4: 54,229,097-54,298,247

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

5159

P09619

chr5: 150,113,837-150,155,872

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

5290

P42336

chr3: 179,148,114-179,240,093

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

5291

P42338

chr3: 138,652,699-138,834,938

PIK3CD

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

5293

O00329

chr1: 9,651,732-9,729,114

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

5295

P27986

chr5: 68,215,720-68,301,821

POLE3

polymerase (DNA directed), epsilon 3, accessory subunit

54107

Q9NRF9

chr9: 113,407,235-113,410,672

POLD1

polymerase (DNA directed), delta 1, catalytic subunit

5424

P28340

chr19: 50,384,204-50,418,018

POLE

polymerase (DNA directed), epsilon, catalytic subunit

5426

Q07864

chr12: 132,623,753-132,687,365

POLE2

polymerase (DNA directed), epsilon 2, accessory subunit

5427

P56282

chr14: 49,643,555-49,688,422

PPP3CA

protein phosphatase 3, catalytic subunit, alpha isozyme

5530

Q08209

chr4: 101,023,409-101,348,278

PPP3R2

protein phosphatase 3 regulatory subunit B, beta

5535

Q96LZ3

chr9: 101,591,615-101,595,021

PRKACA

protein kinase, cAMP-dependent, alpha catalytic subunit

5566

P17612

chr19: 14,091,688-14,118,084

MAPK8

mitogen-activated protein kinase 8

5599

P45983

chr10: 48,306,639-48,439,360

POLE4

polymerase (DNA-directed), epsilon 4, accessory subunit

56655

Q9NR33

chr2: 74,958,492-74,970,128

POLD4

polymerase (DNA-directed), delta 4, accessory subunit

57804

Q9HCU8

chr11: 67,350,777-67,356,972

BAX

BCL2-associated X protein

581

Q07812

chr19: 48,954,815-48,961,798

RANBP1

RAN binding protein 1

5902

P43487

chr22: 20,115,938-20,127,357

RB1

retinoblastoma 1

5925

P06400

chr13: 48,303,751-48,481,986

RELA

v-rel avian reticuloendotheliosis viral oncogene homolog A

5970

Q04206

chr11: 65,653,596-65,663,094

RELB

v-rel avian reticuloendotheliosis viral oncogene homolog B

5971

Q01201

chr19: 45,001,430-45,038,198

RRAS

related RAS viral (r-ras) oncogene homolog

6237

P10301

chr19: 49,635,292-49,640,201

ANAPC1

anaphase promoting complex subunit 1

64682

Q9H1A4

chr2: 111,766,271-111,884,690

CRTC3

CREB regulated transcription coactivator 3

64784

Q6UUV7

chr15: 90,529,925-90,645,345

SLC2A1

solute carrier family 2 (facilitated glucose transporter), member 1

6513

P11166

chr1: 42,925,375-42,959,173

STAT5A

signal transducer and activator of transcription 5A

6776

P42229

chr17: 42,287,547-42,311,943

STAT5B

signal transducer and activator of transcription 5B

6777

P51692

chr17: 42,199,168-42,276,707

TCF3

transcription factor 3

6929

P15923

chr19: 1,609,290-1,652,605

BUB1B

BUB1B, mitotic checkpoint serine/threonine kinase

701

O60566

chr15: 40,161,023-40,221,136

TGFB1

transforming growth factor beta 1

7040

P01137

chr19: 41,301,587-41,353,911

TGFB2

transforming growth factor beta 2

7042

P61812

chr1: 218,346,235-218,444,619

TGFBR1

transforming growth factor beta receptor I

7046

P36897

chr9: 99,104,038-99,154,192

TGFBR2

transforming growth factor beta receptor II

7048

P37173

chr3: 30,606,502-30,694,142

TSPO

translocator protein

706

P30536

chr22: 43,151,514-43,163,242

TLN1

talin 1

7094

Q9Y490

chr9: 35,696,948-35,732,395

TNF

tumor necrosis factor

7124

P01375

chr6: 31,575,567-31,578,336

TP53

tumor protein p53

7157

P04637

chr17: 7,661,779-7,687,550

VCAM1

vascular cell adhesion molecule 1

7412

P19320

chr1: 100,719,742-100,739,045

VDAC2

voltage-dependent anion channel 2

7417

P45880

chr10: 75,210,154-75,231,448

VDAC3

voltage-dependent anion channel 3

7419

Q9Y277

chr8: 42,391,624-42,405,897

WNT2

wingless-type MMTV integration site family member 2

7472

P09544

chr7: 117,276,631-117,323,289

WNT3

wingless-type MMTV integration site family member 3

7473

P56703

chr17: 46,762,506-46,833,154

WNT5A

wingless-type MMTV integration site family member 5A

7474

P41221

chr3: 55,465,715-55,490,539

WNT6

wingless-type MMTV integration site family member 6

7475

Q9Y6F9

chr2: 218,859,821-218,874,233

WNT2B

wingless-type MMTV integration site family member 2B

7482

Q93097

chr1: 112,466,541-112,530,165

XBP1

X-box binding protein 1

7494

P17861

chr22: 28,794,555-28,800,597

XPO1

exportin 1

7514

O14980

chr2: 61,477,849-61,538,626

ZFP36

ZFP36 ring finger protein

7538

P26651

chr19: 39,406,813-39,409,412

IL1R2

interleukin 1 receptor, type II

7850

P27930

chr2: 101,991,844-102,028,544

FOSL1

FOS-like antigen 1

8061

P15407

chr11: 65,892,049-65,900,573

WNT5B

wingless-type MMTV integration site family member 5B

81029

Q9H1J7

chr12: 1,529,891-1,647,243

CALR

calreticulin

811

P27797

chr19: 12,938,578-12,944,489

CANX

calnexin

821

P27824

chr5: 179,678,628-179,730,925

TRRAP

transformation/transcription domain-associated protein

8295

Q9Y4A5

chr7: 98,877,933-99,013,243

FZD4

frizzled class receptor 4

8322

Q9ULV1

chr11: 86,945,679-86,955,391

FZD6

frizzled class receptor 6

8323

O60353

chr8: 103,298,433-103,332,866

FZD7

frizzled class receptor 7

8324

O75084

chr2: 202,034,587-202,038,445

FZD8

frizzled class receptor 8

8325

Q9H461

chr10: 35,638,249-35,642,278

CDC23

cell division cycle 23

8697

Q9UJX2

chr5: 138,187,648-138,213,343

NRP1

neuropilin 1

8829

O14786

chr10: 33,177,492-33,336,262

KAT2B

K(lysine) acetyltransferase 2B

8850

Q92831

chr3: 20,040,023-20,154,404

CCND2

cyclin D2

894

P30279

chr12: 4,273,772-4,305,350

CCND3

cyclin D3

896

P30281

chr6: 41,934,933-42,050,357

CCNB2

cyclin B2

9133

O95067

chr15: 59,105,078-59,125,045

BUB3

BUB3 mitotic checkpoint protein

9184

O43684

chr10: 123,154,277-123,170,467

PTTG1

pituitary tumor-transforming 1

9232

O95997

chr5: 160,421,822-160,428,744

TP53INP1

tumor protein p53 inducible nuclear protein 1

94241

Q96A56

chr8: 94,925,972-94,949,411

CDC20

cell division cycle 20

991

Q12834

chr1: 43,358,955-43,363,203

CDC27

cell division cycle 27

996

P30260

chr17: 47,117,703-47,189,422