Pathway Description

Pathway ID hsa04810
Pathway Term Regulation of actin cytoskeleton
Pathway Source KEGG
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

ARPC4

actin related protein 2/3 complex subunit 4

10093

P59998

chr3: 9,792,495-9,807,726

ARPC3

actin related protein 2/3 complex subunit 3

10094

O15145

chr12: 110,434,825-110,450,422

ARPC2

actin related protein 2/3 complex subunit 2

10109

O15144

chr2: 218,217,094-218,254,356

ABI2

abl-interactor 2

10152

Q9NYB9

chr2: 203,328,219-203,447,723

WASF2

WAS protein family member 2

10163

Q9Y6W5

chr1: 27,404,226-27,490,158

MYL9

myosin light chain 9

10398

P24844

chr20: 36,541,484-36,551,447

VAV3

vav guanine nucleotide exchange factor 3

10451

Q9UKW4

chr1: 107,571,160-107,965,144

MYL12A

myosin light chain 12A

10627

P19105

chr18: 3,247,481-3,256,236

CFL1

cofilin 1 (non-muscle)

1072

P23528

chr11: 65,823,022-65,862,026

IQGAP2

IQ motif containing GTPase activating protein 2

10788

Q13576

chr5: 76,403,249-76,708,132

CHRM2

cholinergic receptor, muscarinic 2

1129

P08172

chr7: 136,868,669-137,020,255

CHRM3

cholinergic receptor, muscarinic 3

1131

P20309

chr1: 239,386,565-239,915,452

IQGAP3

IQ motif containing GTPase activating protein 3

128239

Q86VI3

chr1: 156,525,405-156,572,604

CRKL

v-crk avian sarcoma virus CT10 oncogene homolog-like

1399

P46109

chr22: 20,917,426-20,953,749

DIAPH2

diaphanous related formin 2

1730

O60879

chrX: 96,684,663-97,604,997

EGFR

epidermal growth factor receptor

1956

P00533

chr7: 55,019,021-55,211,628

PIKFYVE

phosphoinositide kinase, FYVE finger containing

200576

Q9Y2I7

chr2: 208,266,267-208,358,751

F2

coagulation factor II (thrombin)

2147

P00734

chr11: 46,719,180-46,739,506

F2R

coagulation factor II (thrombin) receptor

2149

P25116

chr5: 76,716,043-76,735,781

SPATA13

spermatogenesis associated 13

221178

Q96N96

chr13: 23,979,805-24,307,074

FGF2

fibroblast growth factor 2 (basic)

2247

P09038

chr4: 122,826,708-122,898,236

FGF7

fibroblast growth factor 7

2252

P21781

chr15: 49,423,096-49,488,775

FGF9

fibroblast growth factor 9

2254

P31371

chr13: 21,671,383-21,704,498

FGF11

fibroblast growth factor 11

2256

Q92914

chr17: 7,438,273-7,444,937

FGF12

fibroblast growth factor 12

2257

P61328

chr3: 192,139,395-192,767,764

FGF13

fibroblast growth factor 13

2258

Q92913

chrX: 138,614,731-139,222,777

FGF14

fibroblast growth factor 14

2259

Q92915

chr13: 101,710,804-102,402,457

FGFR1

fibroblast growth factor receptor 1

2260

P11362

chr8: 38,411,138-38,468,834

FGFR2

fibroblast growth factor receptor 2

2263

P21802

chr10: 121,478,334-121,598,458

RRAS2

related RAS viral (r-ras) oncogene homolog 2

22800

P62070

chr11: 14,277,926-14,364,506

ITGA11

integrin subunit alpha 11

22801

Q9UKX5

chr15: 68,296,533-68,432,162

CYFIP1

cytoplasmic FMR1 interacting protein 1

23191

Q7L576

chr15: 22,867,052-22,981,063

FN1

fibronectin 1

2335

P02751

chr2: 215,360,440-215,436,172

PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

23396

O60331

chr19: 3,630,183-3,700,479

CYFIP2

cytoplasmic FMR1 interacting protein 2

26999

Q96F07

chr5: 157,266,079-157,395,595

GNA12

guanine nucleotide binding protein (G protein) alpha 12

2768

Q03113

chr7: 2,728,112-2,844,324

GIT1

G protein-coupled receptor kinase interacting ArfGAP 1

28964

Q9Y2X7

chr17: 29,573,469-29,594,054

APC

adenomatous polyposis coli

324

P25054

chr5: 112,707,498-112,846,239

INS

insulin

3630

P01308

chr11: 2,159,779-2,161,341

ITGA6

integrin subunit alpha 6

3655

P23229

chr2: 172,427,354-172,506,282

ITGA2

integrin subunit alpha 2

3673

P17301

chr5: 52,989,326-53,094,779

ITGA3

integrin subunit alpha 3

3675

P26006

chr17: 50,055,968-50,090,481

ITGA5

integrin subunit alpha 5

3678

P08648

chr12: 54,395,261-54,419,460

ITGA9

integrin subunit alpha 9

3680

Q13797

chr3: 37,452,115-37,823,514

ITGAE

integrin subunit alpha E

3682

P38570

chr17: 3,714,628-3,801,243

ITGAM

integrin subunit alpha M

3684

P11215

chr16: 31,259,990-31,332,892

ITGAV

integrin subunit alpha V

3685

P06756

chr2: 186,590,065-186,680,901

ITGAX

integrin subunit alpha X

3687

P20702

chr16: 31,355,134-31,382,997

ITGB1

integrin subunit beta 1

3688

P05556

chr10: 32,900,319-33,005,792

ITGB2

integrin subunit beta 2

3689

P05107

chr21: 44,885,953-44,931,989

ITGB3

integrin subunit beta 3

3690

P05106

chr17: 47,253,846-47,311,816

ITGB4

integrin subunit beta 4

3691

P16144

chr17: 75,721,328-75,757,818

ITGB5

integrin subunit beta 5

3693

P18084

chr3: 124,761,948-124,901,418

ITGB8

integrin subunit beta 8

3696

P26012

chr7: 20,330,702-20,415,754

KRAS

Kirsten rat sarcoma viral oncogene homolog

3845

P01116

chr12: 25,204,789-25,250,936

RHOA

ras homolog family member A

387

P61586

chr3: 49,359,145-49,412,998

LIMK2

LIM domain kinase 2

3985

P53671

chr22: 31,212,239-31,280,080

MYH9

myosin, heavy chain 9, non-muscle

4627

P35579

chr22: 36,281,281-36,388,018

MYL5

myosin light chain 5

4636

Q02045

chr4: 673,580-682,033

MYLK

myosin light chain kinase

4638

Q15746

chr3: 123,610,049-123,884,331

PPP1R12A

protein phosphatase 1 regulatory subunit 12A

4659

O14974

chr12: 79,773,563-79,935,460

PPP1R12B

protein phosphatase 1 regulatory subunit 12B

4660

O60237

chr1: 202,348,699-202,592,706

NRAS

neuroblastoma RAS viral (v-ras) oncogene homolog

4893

P01111

chr1: 114,704,469-114,716,894

PAK2

p21 protein (Cdc42/Rac)-activated kinase 2

5062

Q13177

chr3: 196,739,857-196,832,647

PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

5063

O75914

chrX: 110,944,285-111,227,361

ARHGEF4

Rho guanine nucleotide exchange factor 4

50649

Q9NR80

chr2: 130,836,916-131,047,263

PDGFA

platelet-derived growth factor alpha polypeptide

5154

P04085

chr7: 497,258-520,296

PDGFB

platelet-derived growth factor beta polypeptide

5155

P01127

chr22: 39,223,359-39,244,751

PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

5156

P16234

chr4: 54,229,097-54,298,247

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

5159

P09619

chr5: 150,113,837-150,155,872

PFN1

profilin 1

5216

P07737

chr17: 4,945,652-4,949,061

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

5290

P42336

chr3: 179,148,114-179,240,093

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

5291

P42338

chr3: 138,652,699-138,834,938

PIK3CD

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

5293

O00329

chr1: 9,651,732-9,729,114

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

5295

P27986

chr5: 68,215,720-68,301,821

PIP4K2A

phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

5305

P48426

chr10: 22,534,849-22,714,555

SSH3

slingshot protein phosphatase 3

54961

Q8TE77

chr11: 67,303,448-67,312,607

PPP1CA

protein phosphatase 1, catalytic subunit, alpha isozyme

5499

P62136

chr11: 67,398,183-67,421,183

PPP1CB

protein phosphatase 1, catalytic subunit, beta isozyme

5500

P62140

chr2: 28,751,640-28,802,940

PPP1CC

protein phosphatase 1, catalytic subunit, gamma isozyme

5501

P36873

chr12: 110,719,680-110,742,939

ENAH

enabled homolog (Drosophila)

55740

Q8N8S7

chr1: 225,486,835-225,653,142

MAPK1

mitogen-activated protein kinase 1

5594

P28482

chr22: 21,754,500-21,867,680

MAPK3

mitogen-activated protein kinase 3

5595

P27361

chr16: 30,114,105-30,123,506

PDGFC

platelet derived growth factor C

56034

Q9NRA1

chr4: 156,760,454-156,971,394

MAP2K1

mitogen-activated protein kinase kinase 1

5604

Q02750

chr15: 66,386,817-66,492,312

MAP2K2

mitogen-activated protein kinase kinase 2

5605

P36507

chr19: 4,090,321-4,124,129

PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

57144

Q9P286

chr20: 9,537,389-9,839,041

PTK2

protein tyrosine kinase 2

5747

Q05397

chr8: 140,657,900-141,002,216

MYL7

myosin light chain 7

58498

Q01449

chr7: 44,138,864-44,141,332

RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

5879

P63000

chr7: 6,374,523-6,403,977

RAC2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

5880

P15153

chr22: 37,225,261-37,244,448

RAC3

ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)

5881

P60763

chr17: 82,031,624-82,034,204

RAF1

Raf-1 proto-oncogene, serine/threonine kinase

5894

P04049

chr3: 12,583,601-12,664,226

RDX

radixin

5962

P35241

chr11: 110,174,880-110,296,722

ACTB

actin, beta

60

P60709

chr7: 5,527,151-5,563,784

RRAS

related RAS viral (r-ras) oncogene homolog

6237

P10301

chr19: 49,635,292-49,640,201

SOS1

SOS Ras/Rac guanine nucleotide exchange factor 1

6654

Q07889

chr2: 38,981,396-39,124,345

SOS2

SOS Ras/Rho guanine nucleotide exchange factor 2

6655

Q07890

chr14: 50,117,120-50,231,558

TIAM1

T-cell lymphoma invasion and metastasis 1

7074

Q13009

chr21: 31,118,416-31,559,977

ACTG1

actin gamma 1

71

P63261

chr17: 81,509,971-81,523,847

TMSB4X

thymosin beta 4, X-linked

7114

P62328

chrX: 12,975,108-12,977,227

VAV1

vav guanine nucleotide exchange factor 1

7409

P15498

chr19: 6,772,714-6,857,366

EZR

ezrin

7430

P15311

chr6: 158,765,741-158,819,412

PDGFD

platelet derived growth factor D

80310

Q9GZP0

chr11: 103,907,186-104,164,379

ACTN4

actinin, alpha 4

81

O43707

chr19: 38,647,649-38,731,583

DIAPH3

diaphanous related formin 3

81624

Q9NSV4

chr13: 59,665,583-60,163,987

PIP5K1B

phosphatidylinositol-4-phosphate 5-kinase, type I, beta

8395

O14986

chr9: 68,705,414-69,009,176

PIP4K2B

phosphatidylinositol-5-phosphate 4-kinase, type II, beta

8396

P78356

chr17: 38,765,689-38,800,126

ITGA10

integrin subunit alpha 10

8515

O75578

chr1: 145,891,208-145,910,189

SSH2

slingshot protein phosphatase 2

85464

Q76I76

chr17: 29,625,938-29,930,276

ACTN1

actinin, alpha 1

87

P12814

chr14: 68,874,143-68,979,440

FGF18

fibroblast growth factor 18

8817

O76093

chr5: 171,419,656-171,457,623

IQGAP1

IQ motif containing GTPase activating protein 1

8826

P46940

chr15: 90,388,218-90,502,243

ARHGEF7

Rho guanine nucleotide exchange factor 7

8874

Q14155

chr13: 111,114,559-111,305,737

WASL

Wiskott-Aldrich syndrome-like

8976

O00401

chr7: 123,681,935-123,749,067

CD14

CD14 molecule

929

P08571

chr5: 140,631,728-140,633,701

ROCK2

Rho-associated, coiled-coil containing protein kinase 2

9475

O75116

chr2: 11,179,761-11,348,330

FGF19

fibroblast growth factor 19

9965

O95750

chr11: 69,698,232-69,704,642

CDC42

cell division cycle 42

998

P60953

chr1: 22,052,627-22,092,946