| Pathway ID | hsa04810 |
| Pathway Term | Regulation of actin cytoskeleton |
| Pathway Source | KEGG |
| Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
|---|---|---|---|---|
|
ARPC4 |
actin related protein 2/3 complex subunit 4 |
10093 |
P59998 |
chr3: 9,792,495-9,807,726 |
|
ARPC3 |
actin related protein 2/3 complex subunit 3 |
10094 |
O15145 |
chr12: 110,434,825-110,450,422 |
|
ARPC2 |
actin related protein 2/3 complex subunit 2 |
10109 |
O15144 |
chr2: 218,217,094-218,254,356 |
|
ABI2 |
abl-interactor 2 |
10152 |
Q9NYB9 |
chr2: 203,328,219-203,447,723 |
|
WASF2 |
WAS protein family member 2 |
10163 |
Q9Y6W5 |
chr1: 27,404,226-27,490,158 |
|
MYL9 |
myosin light chain 9 |
10398 |
P24844 |
chr20: 36,541,484-36,551,447 |
|
VAV3 |
vav guanine nucleotide exchange factor 3 |
10451 |
Q9UKW4 |
chr1: 107,571,160-107,965,144 |
|
MYL12A |
myosin light chain 12A |
10627 |
P19105 |
chr18: 3,247,481-3,256,236 |
|
CFL1 |
cofilin 1 (non-muscle) |
1072 |
P23528 |
chr11: 65,823,022-65,862,026 |
|
IQGAP2 |
IQ motif containing GTPase activating protein 2 |
10788 |
Q13576 |
chr5: 76,403,249-76,708,132 |
|
CHRM2 |
cholinergic receptor, muscarinic 2 |
1129 |
P08172 |
chr7: 136,868,669-137,020,255 |
|
CHRM3 |
cholinergic receptor, muscarinic 3 |
1131 |
P20309 |
chr1: 239,386,565-239,915,452 |
|
IQGAP3 |
IQ motif containing GTPase activating protein 3 |
128239 |
Q86VI3 |
chr1: 156,525,405-156,572,604 |
|
CRKL |
v-crk avian sarcoma virus CT10 oncogene homolog-like |
1399 |
P46109 |
chr22: 20,917,426-20,953,749 |
|
DIAPH2 |
diaphanous related formin 2 |
1730 |
O60879 |
chrX: 96,684,663-97,604,997 |
|
EGFR |
epidermal growth factor receptor |
1956 |
P00533 |
chr7: 55,019,021-55,211,628 |
|
PIKFYVE |
phosphoinositide kinase, FYVE finger containing |
200576 |
Q9Y2I7 |
chr2: 208,266,267-208,358,751 |
|
F2 |
coagulation factor II (thrombin) |
2147 |
P00734 |
chr11: 46,719,180-46,739,506 |
|
F2R |
coagulation factor II (thrombin) receptor |
2149 |
P25116 |
chr5: 76,716,043-76,735,781 |
|
SPATA13 |
spermatogenesis associated 13 |
221178 |
Q96N96 |
chr13: 23,979,805-24,307,074 |
|
FGF2 |
fibroblast growth factor 2 (basic) |
2247 |
P09038 |
chr4: 122,826,708-122,898,236 |
|
FGF7 |
fibroblast growth factor 7 |
2252 |
P21781 |
chr15: 49,423,096-49,488,775 |
|
FGF9 |
fibroblast growth factor 9 |
2254 |
P31371 |
chr13: 21,671,383-21,704,498 |
|
FGF11 |
fibroblast growth factor 11 |
2256 |
Q92914 |
chr17: 7,438,273-7,444,937 |
|
FGF12 |
fibroblast growth factor 12 |
2257 |
P61328 |
chr3: 192,139,395-192,767,764 |
|
FGF13 |
fibroblast growth factor 13 |
2258 |
Q92913 |
chrX: 138,614,731-139,222,777 |
|
FGF14 |
fibroblast growth factor 14 |
2259 |
Q92915 |
chr13: 101,710,804-102,402,457 |
|
FGFR1 |
fibroblast growth factor receptor 1 |
2260 |
P11362 |
chr8: 38,411,138-38,468,834 |
|
FGFR2 |
fibroblast growth factor receptor 2 |
2263 |
P21802 |
chr10: 121,478,334-121,598,458 |
|
RRAS2 |
related RAS viral (r-ras) oncogene homolog 2 |
22800 |
P62070 |
chr11: 14,277,926-14,364,506 |
|
ITGA11 |
integrin subunit alpha 11 |
22801 |
Q9UKX5 |
chr15: 68,296,533-68,432,162 |
|
CYFIP1 |
cytoplasmic FMR1 interacting protein 1 |
23191 |
Q7L576 |
chr15: 22,867,052-22,981,063 |
|
FN1 |
fibronectin 1 |
2335 |
P02751 |
chr2: 215,360,440-215,436,172 |
|
PIP5K1C |
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
23396 |
O60331 |
chr19: 3,630,183-3,700,479 |
|
CYFIP2 |
cytoplasmic FMR1 interacting protein 2 |
26999 |
Q96F07 |
chr5: 157,266,079-157,395,595 |
|
GNA12 |
guanine nucleotide binding protein (G protein) alpha 12 |
2768 |
Q03113 |
chr7: 2,728,112-2,844,324 |
|
GIT1 |
G protein-coupled receptor kinase interacting ArfGAP 1 |
28964 |
Q9Y2X7 |
chr17: 29,573,469-29,594,054 |
|
APC |
adenomatous polyposis coli |
324 |
P25054 |
chr5: 112,707,498-112,846,239 |
|
INS |
insulin |
3630 |
P01308 |
chr11: 2,159,779-2,161,341 |
|
ITGA6 |
integrin subunit alpha 6 |
3655 |
P23229 |
chr2: 172,427,354-172,506,282 |
|
ITGA2 |
integrin subunit alpha 2 |
3673 |
P17301 |
chr5: 52,989,326-53,094,779 |
|
ITGA3 |
integrin subunit alpha 3 |
3675 |
P26006 |
chr17: 50,055,968-50,090,481 |
|
ITGA5 |
integrin subunit alpha 5 |
3678 |
P08648 |
chr12: 54,395,261-54,419,460 |
|
ITGA9 |
integrin subunit alpha 9 |
3680 |
Q13797 |
chr3: 37,452,115-37,823,514 |
|
ITGAE |
integrin subunit alpha E |
3682 |
P38570 |
chr17: 3,714,628-3,801,243 |
|
ITGAM |
integrin subunit alpha M |
3684 |
P11215 |
chr16: 31,259,990-31,332,892 |
|
ITGAV |
integrin subunit alpha V |
3685 |
P06756 |
chr2: 186,590,065-186,680,901 |
|
ITGAX |
integrin subunit alpha X |
3687 |
P20702 |
chr16: 31,355,134-31,382,997 |
|
ITGB1 |
integrin subunit beta 1 |
3688 |
P05556 |
chr10: 32,900,319-33,005,792 |
|
ITGB2 |
integrin subunit beta 2 |
3689 |
P05107 |
chr21: 44,885,953-44,931,989 |
|
ITGB3 |
integrin subunit beta 3 |
3690 |
P05106 |
chr17: 47,253,846-47,311,816 |
|
ITGB4 |
integrin subunit beta 4 |
3691 |
P16144 |
chr17: 75,721,328-75,757,818 |
|
ITGB5 |
integrin subunit beta 5 |
3693 |
P18084 |
chr3: 124,761,948-124,901,418 |
|
ITGB8 |
integrin subunit beta 8 |
3696 |
P26012 |
chr7: 20,330,702-20,415,754 |
|
KRAS |
Kirsten rat sarcoma viral oncogene homolog |
3845 |
P01116 |
chr12: 25,204,789-25,250,936 |
|
RHOA |
ras homolog family member A |
387 |
P61586 |
chr3: 49,359,145-49,412,998 |
|
LIMK2 |
LIM domain kinase 2 |
3985 |
P53671 |
chr22: 31,212,239-31,280,080 |
|
MYH9 |
myosin, heavy chain 9, non-muscle |
4627 |
P35579 |
chr22: 36,281,281-36,388,018 |
|
MYL5 |
myosin light chain 5 |
4636 |
Q02045 |
chr4: 673,580-682,033 |
|
MYLK |
myosin light chain kinase |
4638 |
Q15746 |
chr3: 123,610,049-123,884,331 |
|
PPP1R12A |
protein phosphatase 1 regulatory subunit 12A |
4659 |
O14974 |
chr12: 79,773,563-79,935,460 |
|
PPP1R12B |
protein phosphatase 1 regulatory subunit 12B |
4660 |
O60237 |
chr1: 202,348,699-202,592,706 |
|
NRAS |
neuroblastoma RAS viral (v-ras) oncogene homolog |
4893 |
P01111 |
chr1: 114,704,469-114,716,894 |
|
PAK2 |
p21 protein (Cdc42/Rac)-activated kinase 2 |
5062 |
Q13177 |
chr3: 196,739,857-196,832,647 |
|
PAK3 |
p21 protein (Cdc42/Rac)-activated kinase 3 |
5063 |
O75914 |
chrX: 110,944,285-111,227,361 |
|
ARHGEF4 |
Rho guanine nucleotide exchange factor 4 |
50649 |
Q9NR80 |
chr2: 130,836,916-131,047,263 |
|
PDGFA |
platelet-derived growth factor alpha polypeptide |
5154 |
P04085 |
chr7: 497,258-520,296 |
|
PDGFB |
platelet-derived growth factor beta polypeptide |
5155 |
P01127 |
chr22: 39,223,359-39,244,751 |
|
PDGFRA |
platelet-derived growth factor receptor, alpha polypeptide |
5156 |
P16234 |
chr4: 54,229,097-54,298,247 |
|
PDGFRB |
platelet-derived growth factor receptor, beta polypeptide |
5159 |
P09619 |
chr5: 150,113,837-150,155,872 |
|
PFN1 |
profilin 1 |
5216 |
P07737 |
chr17: 4,945,652-4,949,061 |
|
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
5290 |
P42336 |
chr3: 179,148,114-179,240,093 |
|
PIK3CB |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
5291 |
P42338 |
chr3: 138,652,699-138,834,938 |
|
PIK3CD |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
5293 |
O00329 |
chr1: 9,651,732-9,729,114 |
|
PIK3R1 |
phosphoinositide-3-kinase regulatory subunit 1 |
5295 |
P27986 |
chr5: 68,215,720-68,301,821 |
|
PIP4K2A |
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha |
5305 |
P48426 |
chr10: 22,534,849-22,714,555 |
|
SSH3 |
slingshot protein phosphatase 3 |
54961 |
Q8TE77 |
chr11: 67,303,448-67,312,607 |
|
PPP1CA |
protein phosphatase 1, catalytic subunit, alpha isozyme |
5499 |
P62136 |
chr11: 67,398,183-67,421,183 |
|
PPP1CB |
protein phosphatase 1, catalytic subunit, beta isozyme |
5500 |
P62140 |
chr2: 28,751,640-28,802,940 |
|
PPP1CC |
protein phosphatase 1, catalytic subunit, gamma isozyme |
5501 |
P36873 |
chr12: 110,719,680-110,742,939 |
|
ENAH |
enabled homolog (Drosophila) |
55740 |
Q8N8S7 |
chr1: 225,486,835-225,653,142 |
|
MAPK1 |
mitogen-activated protein kinase 1 |
5594 |
P28482 |
chr22: 21,754,500-21,867,680 |
|
MAPK3 |
mitogen-activated protein kinase 3 |
5595 |
P27361 |
chr16: 30,114,105-30,123,506 |
|
PDGFC |
platelet derived growth factor C |
56034 |
Q9NRA1 |
chr4: 156,760,454-156,971,394 |
|
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
5604 |
Q02750 |
chr15: 66,386,817-66,492,312 |
|
MAP2K2 |
mitogen-activated protein kinase kinase 2 |
5605 |
P36507 |
chr19: 4,090,321-4,124,129 |
|
PAK7 |
p21 protein (Cdc42/Rac)-activated kinase 7 |
57144 |
Q9P286 |
chr20: 9,537,389-9,839,041 |
|
PTK2 |
protein tyrosine kinase 2 |
5747 |
Q05397 |
chr8: 140,657,900-141,002,216 |
|
MYL7 |
myosin light chain 7 |
58498 |
Q01449 |
chr7: 44,138,864-44,141,332 |
|
RAC1 |
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
5879 |
P63000 |
chr7: 6,374,523-6,403,977 |
|
RAC2 |
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
5880 |
P15153 |
chr22: 37,225,261-37,244,448 |
|
RAC3 |
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
5881 |
P60763 |
chr17: 82,031,624-82,034,204 |
|
RAF1 |
Raf-1 proto-oncogene, serine/threonine kinase |
5894 |
P04049 |
chr3: 12,583,601-12,664,226 |
|
RDX |
radixin |
5962 |
P35241 |
chr11: 110,174,880-110,296,722 |
|
ACTB |
actin, beta |
60 |
P60709 |
chr7: 5,527,151-5,563,784 |
|
RRAS |
related RAS viral (r-ras) oncogene homolog |
6237 |
P10301 |
chr19: 49,635,292-49,640,201 |
|
SOS1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
6654 |
Q07889 |
chr2: 38,981,396-39,124,345 |
|
SOS2 |
SOS Ras/Rho guanine nucleotide exchange factor 2 |
6655 |
Q07890 |
chr14: 50,117,120-50,231,558 |
|
TIAM1 |
T-cell lymphoma invasion and metastasis 1 |
7074 |
Q13009 |
chr21: 31,118,416-31,559,977 |
|
ACTG1 |
actin gamma 1 |
71 |
P63261 |
chr17: 81,509,971-81,523,847 |
|
TMSB4X |
thymosin beta 4, X-linked |
7114 |
P62328 |
chrX: 12,975,108-12,977,227 |
|
VAV1 |
vav guanine nucleotide exchange factor 1 |
7409 |
P15498 |
chr19: 6,772,714-6,857,366 |
|
EZR |
ezrin |
7430 |
P15311 |
chr6: 158,765,741-158,819,412 |
|
PDGFD |
platelet derived growth factor D |
80310 |
Q9GZP0 |
chr11: 103,907,186-104,164,379 |
|
ACTN4 |
actinin, alpha 4 |
81 |
O43707 |
chr19: 38,647,649-38,731,583 |
|
DIAPH3 |
diaphanous related formin 3 |
81624 |
Q9NSV4 |
chr13: 59,665,583-60,163,987 |
|
PIP5K1B |
phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
8395 |
O14986 |
chr9: 68,705,414-69,009,176 |
|
PIP4K2B |
phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
8396 |
P78356 |
chr17: 38,765,689-38,800,126 |
|
ITGA10 |
integrin subunit alpha 10 |
8515 |
O75578 |
chr1: 145,891,208-145,910,189 |
|
SSH2 |
slingshot protein phosphatase 2 |
85464 |
Q76I76 |
chr17: 29,625,938-29,930,276 |
|
ACTN1 |
actinin, alpha 1 |
87 |
P12814 |
chr14: 68,874,143-68,979,440 |
|
FGF18 |
fibroblast growth factor 18 |
8817 |
O76093 |
chr5: 171,419,656-171,457,623 |
|
IQGAP1 |
IQ motif containing GTPase activating protein 1 |
8826 |
P46940 |
chr15: 90,388,218-90,502,243 |
|
ARHGEF7 |
Rho guanine nucleotide exchange factor 7 |
8874 |
Q14155 |
chr13: 111,114,559-111,305,737 |
|
WASL |
Wiskott-Aldrich syndrome-like |
8976 |
O00401 |
chr7: 123,681,935-123,749,067 |
|
CD14 |
CD14 molecule |
929 |
P08571 |
chr5: 140,631,728-140,633,701 |
|
ROCK2 |
Rho-associated, coiled-coil containing protein kinase 2 |
9475 |
O75116 |
chr2: 11,179,761-11,348,330 |
|
FGF19 |
fibroblast growth factor 19 |
9965 |
O95750 |
chr11: 69,698,232-69,704,642 |
|
CDC42 |
cell division cycle 42 |
998 |
P60953 |
chr1: 22,052,627-22,092,946 |