Pathway Description

Pathway ID hsa04670
Pathway Term Leukocyte transendothelial migration
Pathway Source KEGG
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

CDH5

cadherin 5, type 2 (vascular endothelium)

1003

P33151

chr16: 66,366,622-66,404,786

OCLN

occludin

100506658

Q16625

chr5: 69,492,292-69,558,104

MYL9

myosin light chain 9

10398

P24844

chr20: 36,541,484-36,551,447

VAV3

vav guanine nucleotide exchange factor 3

10451

Q9UKW4

chr1: 107,571,160-107,965,144

MYL12A

myosin light chain 12A

10627

P19105

chr18: 3,247,481-3,256,236

RAPGEF4

Rap guanine nucleotide exchange factor 4

11069

Q8WZA2

chr2: 172,735,274-173,052,893

CLDN4

claudin 4

1364

O14493

chr7: 73,799,542-73,832,693

CLDN3

claudin 3

1365

O15551

chr7: 73,768,997-73,770,270

MAPK14

mitogen-activated protein kinase 14

1432

Q16539

chr6: 36,027,677-36,111,236

CTNNA1

catenin alpha 1

1495

P35221

chr5: 138,610,967-138,935,034

CTNNA2

catenin alpha 2

1496

P26232

chr2: 79,185,231-80,648,861

CTNNB1

catenin beta 1

1499

P35222

chr3: 41,194,837-41,260,096

CTNND1

catenin delta 1

1500

O60716

chr11: 57,753,243-57,819,546

CYBB

cytochrome b-245, beta polypeptide

1536

P04839

chrX: 37,780,011-37,813,461

GNAI1

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1

2770

P63096

chr7: 80,133,955-80,219,402

GNAI2

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

2771

P04899

chr3: 50,226,292-50,259,355

GNAI3

guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3

2773

P08754

chr1: 109,548,611-109,618,321

ICAM1

intercellular adhesion molecule 1

3383

P05362

chr19: 10,270,835-10,286,615

ITGAM

integrin subunit alpha M

3684

P11215

chr16: 31,259,990-31,332,892

ITGB1

integrin subunit beta 1

3688

P05556

chr10: 32,900,319-33,005,792

ITGB2

integrin subunit beta 2

3689

P05107

chr21: 44,885,953-44,931,989

RHOA

ras homolog family member A

387

P61586

chr3: 49,359,145-49,412,998

ARHGAP5

Rho GTPase activating protein 5

394

Q13017

chr14: 32,076,114-32,159,728

CD99

CD99 molecule

4267

P14209

chrX: 2,691,179-2,741,309

MMP2

matrix metallopeptidase 2

4313

P08253

chr16: 55,389,700-55,506,691

MMP9

matrix metallopeptidase 9

4318

P14780

chr20: 46,008,908-46,016,561

MYL5

myosin light chain 5

4636

Q02045

chr4: 673,580-682,033

NCF2

neutrophil cytosolic factor 2

4688

P19878

chr1: 183,555,563-183,590,876

NCF4

neutrophil cytosolic factor 4

4689

Q15080

chr22: 36,860,988-36,878,015

F11R

F11 receptor

50848

Q9Y624

chr1: 160,995,211-161,021,348

PECAM1

platelet/endothelial cell adhesion molecule 1

5175

P16284

chr17: 64,319,415-64,413,776

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

5290

P42336

chr3: 179,148,114-179,240,093

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

5291

P42338

chr3: 138,652,699-138,834,938

PIK3CD

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

5293

O00329

chr1: 9,651,732-9,729,114

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

5295

P27986

chr5: 68,215,720-68,301,821

PLCG2

phospholipase C gamma 2

5336

P16885

chr16: 81,739,097-81,962,693

PRKCA

protein kinase C, alpha

5578

P17252

chr17: 66,302,636-66,810,743

PRKCB

protein kinase C, beta

5579

P05771

chr16: 23,836,001-24,220,611

MAPK13

mitogen-activated protein kinase 13

5603

O15264

chr6: 36,127,809-36,144,524

PTK2

protein tyrosine kinase 2

5747

Q05397

chr8: 140,657,900-141,002,216

PTPN11

protein tyrosine phosphatase, non-receptor type 11

5781

Q06124

chr12: 112,418,351-112,509,913

JAM2

junctional adhesion molecule 2

58494

P57087

chr21: 25,639,272-25,717,562

MYL7

myosin light chain 7

58498

Q01449

chr7: 44,138,864-44,141,332

RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

5879

P63000

chr7: 6,374,523-6,403,977

RAC2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

5880

P15153

chr22: 37,225,261-37,244,448

RAP1A

RAP1A, member of RAS oncogene family

5906

P62834

chr1: 111,542,218-111,716,691

ACTB

actin, beta

60

P60709

chr7: 5,527,151-5,563,784

CXCL12

chemokine (C-X-C motif) ligand 12

6387

P48061

chr10: 44,370,165-44,386,493

ACTG1

actin gamma 1

71

P63261

chr17: 81,509,971-81,523,847

VAV1

vav guanine nucleotide exchange factor 1

7409

P15498

chr19: 6,772,714-6,857,366

VCAM1

vascular cell adhesion molecule 1

7412

P19320

chr1: 100,719,742-100,739,045

EZR

ezrin

7430

P15311

chr6: 158,765,741-158,819,412

CXCR4

chemokine (C-X-C motif) receptor 4

7852

P61073

chr2: 136,114,349-136,118,165

ACTN4

actinin, alpha 4

81

O43707

chr19: 38,647,649-38,731,583

RASSF5

Ras association (RalGDS/AF-6) domain family member 5

83593

Q8WWW0

chr1: 206,507,530-206,589,448

JAM3

junctional adhesion molecule 3

83700

Q9BX67

chr11: 134,068,925-134,152,001

ACTN1

actinin, alpha 1

87

P12814

chr14: 68,874,143-68,979,440

CLDN1

claudin 1

9076

O95832

chr3: 190,305,701-190,322,475

ROCK2

Rho-associated, coiled-coil containing protein kinase 2

9475

O75116

chr2: 11,179,761-11,348,330

CDC42

cell division cycle 42

998

P60953

chr1: 22,052,627-22,092,946