Pathway ID | hsa04668 |
Pathway Term | TNF signaling pathway |
Pathway Source | KEGG |
Gene Symbol | Description | Entrez ID | Uniprot ID | Chromosomal Location |
---|---|---|---|---|
AKT3 |
v-akt murine thymoma viral oncogene homolog 3 |
10000 |
Q9Y243 |
chr1: 243,488,233-243,851,079 |
TAB1 |
TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
10454 |
Q15750 |
chr22: 39,399,741-39,437,060 |
CEBPB |
CCAAT/enhancer binding protein (C/EBP), beta |
1051 |
P17676 |
chr20: 50,190,734-50,192,689 |
MAP3K8 |
mitogen-activated protein kinase kinase kinase 8 |
1326 |
P41279 |
chr10: 30,433,937-30,461,833 |
CREB1 |
cAMP responsive element binding protein 1 |
1385 |
P16220 |
chr2: 207,529,737-207,603,431 |
MAPK14 |
mitogen-activated protein kinase 14 |
1432 |
Q16539 |
chr6: 36,027,677-36,111,236 |
JAG1 |
jagged 1 |
182 |
P78504 |
chr20: 10,637,684-10,674,107 |
EDN1 |
endothelin 1 |
1906 |
P05305 |
chr6: 12,290,363-12,297,194 |
AKT1 |
v-akt murine thymoma viral oncogene homolog 1 |
207 |
P31749 |
chr14: 104,769,349-104,795,751 |
AKT2 |
v-akt murine thymoma viral oncogene homolog 2 |
208 |
P31751 |
chr19: 40,230,317-40,285,536 |
FOS |
FBJ murine osteosarcoma viral oncogene homolog |
2353 |
P01100 |
chr14: 75,278,774-75,282,230 |
TAB3 |
TGF-beta activated kinase 1/MAP3K7 binding protein 3 |
257397 |
Q8N5C8 |
chrX: 30,827,442-30,975,084 |
CXCL1 |
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
2919 |
P09341 |
chr4: 73,869,393-73,871,242 |
CXCL2 |
chemokine (C-X-C motif) ligand 2 |
2920 |
P19875 |
chr4: 74,097,035-74,099,293 |
BIRC3 |
baculoviral IAP repeat containing 3 |
330 |
Q13489 |
chr11: 102,317,450-102,339,403 |
ICAM1 |
intercellular adhesion molecule 1 |
3383 |
P05362 |
chr19: 10,270,835-10,286,615 |
FAS |
Fas cell surface death receptor |
355 |
P25445 |
chr10: 88,990,582-89,015,785 |
IL1B |
interleukin 1 beta |
3553 |
P01584 |
chr2: 112,829,751-112,836,903 |
IL6 |
interleukin 6 |
3569 |
P05231 |
chr7: 22,725,884-22,732,002 |
JUN |
jun proto-oncogene |
3725 |
P05412 |
chr1: 58,780,788-58,784,327 |
JUNB |
jun B proto-oncogene |
3726 |
P17275 |
chr19: 12,791,496-12,793,315 |
LIF |
leukemia inhibitory factor |
3976 |
P15018 |
chr22: 30,240,447-30,246,851 |
MAP3K5 |
mitogen-activated protein kinase kinase kinase 5 |
4217 |
Q99683 |
chr6: 136,557,047-136,792,518 |
MMP9 |
matrix metallopeptidase 9 |
4318 |
P14780 |
chr20: 46,008,908-46,016,561 |
MMP14 |
matrix metallopeptidase 14 |
4323 |
P50281 |
chr14: 22,836,557-22,849,027 |
ATF4 |
activating transcription factor 4 |
468 |
P18848 |
chr22: 39,519,695-39,522,685 |
NFKB1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
4790 |
P19838 |
chr4: 102,501,329-102,617,302 |
PIK3CA |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha |
5290 |
P42336 |
chr3: 179,148,114-179,240,093 |
PIK3CB |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta |
5291 |
P42338 |
chr3: 138,652,699-138,834,938 |
PIK3CD |
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta |
5293 |
O00329 |
chr1: 9,651,732-9,729,114 |
PIK3R1 |
phosphoinositide-3-kinase regulatory subunit 1 |
5295 |
P27986 |
chr5: 68,215,720-68,301,821 |
MAPK1 |
mitogen-activated protein kinase 1 |
5594 |
P28482 |
chr22: 21,754,500-21,867,680 |
MAPK3 |
mitogen-activated protein kinase 3 |
5595 |
P27361 |
chr16: 30,114,105-30,123,506 |
MAPK8 |
mitogen-activated protein kinase 8 |
5599 |
P45983 |
chr10: 48,306,639-48,439,360 |
MAPK9 |
mitogen-activated protein kinase 9 |
5601 |
P45984 |
chr5: 180,233,143-180,292,099 |
MAPK13 |
mitogen-activated protein kinase 13 |
5603 |
O15264 |
chr6: 36,127,809-36,144,524 |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
5604 |
Q02750 |
chr15: 66,386,817-66,492,312 |
MAP2K6 |
mitogen-activated protein kinase kinase 6 |
5608 |
P52564 |
chr17: 69,414,698-69,543,331 |
MAP2K7 |
mitogen-activated protein kinase kinase 7 |
5609 |
O14733 |
chr19: 7,903,843-7,914,478 |
PTGS2 |
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
5743 |
P35354 |
chr1: 186,671,791-186,680,427 |
RELA |
v-rel avian reticuloendotheliosis viral oncogene homolog A |
5970 |
Q04206 |
chr11: 65,653,596-65,663,094 |
BCL3 |
B-cell CLL/lymphoma 3 |
602 |
P20749 |
chr19: 44,747,705-44,760,044 |
CCL2 |
chemokine (C-C motif) ligand 2 |
6347 |
P13500 |
chr17: 34,255,218-34,257,203 |
CCL5 |
chemokine (C-C motif) ligand 5 |
6352 |
P13501 |
chr17: 35,871,491-35,880,793 |
CCL20 |
chemokine (C-C motif) ligand 20 |
6364 |
P78556 |
chr2: 227,813,842-227,817,564 |
CXCL5 |
chemokine (C-X-C motif) ligand 5 |
6374 |
P42830 |
chr4: 73,995,642-73,998,779 |
SELE |
selectin E |
6401 |
P16581 |
chr1: 169,722,641-169,764,705 |
MAP3K7 |
mitogen-activated protein kinase kinase kinase 7 |
6885 |
O43318 |
chr6: 90,513,573-90,587,045 |
TNF |
tumor necrosis factor |
7124 |
P01375 |
chr6: 31,575,567-31,578,336 |
TNFAIP3 |
TNF alpha induced protein 3 |
7128 |
P21580 |
chr6: 137,867,188-137,883,312 |
TNFRSF1B |
tumor necrosis factor receptor superfamily member 1B |
7133 |
P20333 |
chr1: 12,167,003-12,209,228 |
TRAF1 |
TNF receptor associated factor 1 |
7185 |
Q13077 |
chr9: 120,902,393-120,929,173 |
VCAM1 |
vascular cell adhesion molecule 1 |
7412 |
P19320 |
chr1: 100,719,742-100,739,045 |
VEGFC |
vascular endothelial growth factor C |
7424 |
P49767 |
chr4: 176,683,538-176,792,727 |
ITCH |
itchy E3 ubiquitin protein ligase |
83737 |
Q96J02 |
chr20: 34,363,235-34,511,393 |
CASP8 |
caspase 8 |
841 |
Q14790 |
chr2: 201,233,443-201,287,711 |
TRADD |
TNFRSF1A-associated via death domain |
8717 |
Q15628 |
chr16: 67,154,180-67,160,298 |
RIPK1 |
receptor interacting serine/threonine kinase 1 |
8737 |
Q13546 |
chr6: 3,063,991-3,115,187 |
FADD |
Fas associated via death domain |
8772 |
Q13158 |
chr11: 70,203,163-70,207,390 |
IL18R1 |
interleukin 18 receptor 1 |
8809 |
Q13478 |
chr2: 102,311,529-102,398,775 |
CFLAR |
CASP8 and FADD like apoptosis regulator |
8837 |
O15519 |
chr2: 201,116,104-201,176,687 |
SOCS3 |
suppressor of cytokine signaling 3 |
9021 |
O14543 |
chr17: 78,356,778-78,360,077 |
CREB3L1 |
cAMP responsive element binding protein 3-like 1 |
90993 |
Q96BA8 |
chr11: 46,277,661-46,321,422 |
RPS6KA5 |
ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
9252 |
O75582 |
chr14: 90,847,862-91,060,636 |
CREB5 |
cAMP responsive element binding protein 5 |
9586 |
Q02930 |
chr7: 28,299,321-28,825,894 |