Pathway Description

Pathway ID WP51
Pathway Term Regulation of Actin Cytoskeleton
Pathway Source WikiPathways
Gene Symbol Description Entrez ID Uniprot ID Chromosomal Location

ABI2

abl-interactor 2

10152

Q9NYB9

chr2: 203,328,219-203,447,723

F2

coagulation factor II (thrombin)

2147

P00734

chr11: 46,719,180-46,739,506

F2R

coagulation factor II (thrombin) receptor

2149

P25116

chr5: 76,716,043-76,735,781

FN1

fibronectin 1

2335

P02751

chr2: 215,360,440-215,436,172

ENAH

enabled homolog (Drosophila)

55740

Q8N8S7

chr1: 225,486,835-225,653,142

SSH2

slingshot protein phosphatase 2

85464

Q76I76

chr17: 29,625,938-29,930,276

RRAS2

related RAS viral (r-ras) oncogene homolog 2

22800

P62070

chr11: 14,277,926-14,364,506

PDGFRB

platelet-derived growth factor receptor, beta polypeptide

5159

P09619

chr5: 150,113,837-150,155,872

PIP4K2B

phosphatidylinositol-5-phosphate 4-kinase, type II, beta

8396

P78356

chr17: 38,765,689-38,800,126

WASF2

WAS protein family member 2

10163

Q9Y6W5

chr1: 27,404,226-27,490,158

PTK2

protein tyrosine kinase 2

5747

Q05397

chr8: 140,657,900-141,002,216

DIAPH3

diaphanous related formin 3

81624

Q9NSV4

chr13: 59,665,583-60,163,987

ARHGEF7

Rho guanine nucleotide exchange factor 7

8874

Q14155

chr13: 111,114,559-111,305,737

VAV1

vav guanine nucleotide exchange factor 1

7409

P15498

chr19: 6,772,714-6,857,366

PIP5K1B

phosphatidylinositol-4-phosphate 5-kinase, type I, beta

8395

O14986

chr9: 68,705,414-69,009,176

CD14

CD14 molecule

929

P08571

chr5: 140,631,728-140,633,701

NRAS

neuroblastoma RAS viral (v-ras) oncogene homolog

4893

P01111

chr1: 114,704,469-114,716,894

PFN1

profilin 1

5216

P07737

chr17: 4,945,652-4,949,061

GNA12

guanine nucleotide binding protein (G protein) alpha 12

2768

Q03113

chr7: 2,728,112-2,844,324

KRAS

Kirsten rat sarcoma viral oncogene homolog

3845

P01116

chr12: 25,204,789-25,250,936

CHRM2

cholinergic receptor, muscarinic 2

1129

P08172

chr7: 136,868,669-137,020,255

CFL1

cofilin 1 (non-muscle)

1072

P23528

chr11: 65,823,022-65,862,026

MYLK

myosin light chain kinase

4638

Q15746

chr3: 123,610,049-123,884,331

CHRM3

cholinergic receptor, muscarinic 3

1131

P20309

chr1: 239,386,565-239,915,452

PIP5K1C

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma

23396

O60331

chr19: 3,630,183-3,700,479

RDX

radixin

5962

P35241

chr11: 110,174,880-110,296,722

CYFIP2

cytoplasmic FMR1 interacting protein 2

26999

Q96F07

chr5: 157,266,079-157,395,595

PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

57144

Q9P286

chr20: 9,537,389-9,839,041

CSK

c-src tyrosine kinase

1445

P41240

chr15: 74,782,057-74,803,198

PDGFA

platelet-derived growth factor alpha polypeptide

5154

P04085

chr7: 497,258-520,296

PDGFB

platelet-derived growth factor beta polypeptide

5155

P01127

chr22: 39,223,359-39,244,751

PDGFRA

platelet-derived growth factor receptor, alpha polypeptide

5156

P16234

chr4: 54,229,097-54,298,247

TMSB4X

thymosin beta 4, X-linked

7114

P62328

chrX: 12,975,108-12,977,227

APC

adenomatous polyposis coli

324

P25054

chr5: 112,707,498-112,846,239

EZR

ezrin

7430

P15311

chr6: 158,765,741-158,819,412

CDC42

cell division cycle 42

998

P60953

chr1: 22,052,627-22,092,946

SOS2

SOS Ras/Rho guanine nucleotide exchange factor 2

6655

Q07890

chr14: 50,117,120-50,231,558

PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

5063

O75914

chrX: 110,944,285-111,227,361

RAF1

Raf-1 proto-oncogene, serine/threonine kinase

5894

P04049

chr3: 12,583,601-12,664,226

ARHGEF4

Rho guanine nucleotide exchange factor 4

50649

Q9NR80

chr2: 130,836,916-131,047,263

FGF9

fibroblast growth factor 9

2254

P31371

chr13: 21,671,383-21,704,498

FGF7

fibroblast growth factor 7

2252

P21781

chr15: 49,423,096-49,488,775

PAK2

p21 protein (Cdc42/Rac)-activated kinase 2

5062

Q13177

chr3: 196,739,857-196,832,647

FGF2

fibroblast growth factor 2 (basic)

2247

P09038

chr4: 122,826,708-122,898,236

RHOA

ras homolog family member A

387

P61586

chr3: 49,359,145-49,412,998

PPP1R12A

protein phosphatase 1 regulatory subunit 12A

4659

O14974

chr12: 79,773,563-79,935,460

ACTN1

actinin, alpha 1

87

P12814

chr14: 68,874,143-68,979,440

RAC2

ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

5880

P15153

chr22: 37,225,261-37,244,448

MAP2K2

mitogen-activated protein kinase kinase 2

5605

P36507

chr19: 4,090,321-4,124,129

RAC3

ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)

5881

P60763

chr17: 82,031,624-82,034,204

PIK3R4

phosphoinositide-3-kinase regulatory subunit 4

30849

Q99570

chr3: 130,678,935-130,746,829

MAP2K1

mitogen-activated protein kinase kinase 1

5604

Q02750

chr15: 66,386,817-66,492,312

FGFR2

fibroblast growth factor receptor 2

2263

P21802

chr10: 121,478,334-121,598,458

FGFR1

fibroblast growth factor receptor 1

2260

P11362

chr8: 38,411,138-38,468,834

SSH3

slingshot protein phosphatase 3

54961

Q8TE77

chr11: 67,303,448-67,312,607

FGF14

fibroblast growth factor 14

2259

Q92915

chr13: 101,710,804-102,402,457

FGF11

fibroblast growth factor 11

2256

Q92914

chr17: 7,438,273-7,444,937

IQGAP1

IQ motif containing GTPase activating protein 1

8826

P46940

chr15: 90,388,218-90,502,243

FGF12

fibroblast growth factor 12

2257

P61328

chr3: 192,139,395-192,767,764

FGF13

fibroblast growth factor 13

2258

Q92913

chrX: 138,614,731-139,222,777

MAPK3

mitogen-activated protein kinase 3

5595

P27361

chr16: 30,114,105-30,123,506

ACTG1

actin gamma 1

71

P63261

chr17: 81,509,971-81,523,847

FGF19

fibroblast growth factor 19

9965

O95750

chr11: 69,698,232-69,704,642

RAC1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

5879

P63000

chr7: 6,374,523-6,403,977

SOS1

SOS Ras/Rac guanine nucleotide exchange factor 1

6654

Q07889

chr2: 38,981,396-39,124,345

MAPK1

mitogen-activated protein kinase 1

5594

P28482

chr22: 21,754,500-21,867,680

EGFR

epidermal growth factor receptor

1956

P00533

chr7: 55,019,021-55,211,628

RRAS

related RAS viral (r-ras) oncogene homolog

6237

P10301

chr19: 49,635,292-49,640,201

FGF18

fibroblast growth factor 18

8817

O76093

chr5: 171,419,656-171,457,623

PIK3C3

phosphatidylinositol 3-kinase catalytic subunit type 3

5289

Q8NEB9

chr18: 41,955,206-42,087,830

PIP4K2A

phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

5305

P48426

chr10: 22,534,849-22,714,555

ACTB

actin, beta

60

P60709

chr7: 5,527,151-5,563,784

PIK3C2A

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha

5286

O00443

chr11: 17,077,730-17,207,983

ROCK2

Rho-associated, coiled-coil containing protein kinase 2

9475

O75116

chr2: 11,179,761-11,348,330

GIT1

G protein-coupled receptor kinase interacting ArfGAP 1

28964

Q9Y2X7

chr17: 29,573,469-29,594,054

PIK3CA

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

5290

P42336

chr3: 179,148,114-179,240,093

PIK3CB

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

5291

P42338

chr3: 138,652,699-138,834,938

PIK3CD

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

5293

O00329

chr1: 9,651,732-9,729,114

PIK3CG

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

5294

P48736

chr7: 106,865,278-106,907,145

PIK3R1

phosphoinositide-3-kinase regulatory subunit 1

5295

P27986

chr5: 68,215,720-68,301,821