Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:2000649

BP

regulation of sodium ion transmembrane transporter activity

Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.

FXYD1, FXYD4, FGF12, YWHAH, RANGRF

GO:2000650

BP

negative regulation of sodium ion transmembrane transporter activity

Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity.

CAMK2D, PCSK9, OSR1, NEDD4L

GO:2000651

BP

positive regulation of sodium ion transmembrane transporter activity

Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.

DMD, GLRX, ANK3, WNK3

GO:2000653

BP

regulation of genetic imprinting

Any process that modulates the frequency, rate or extent of genetic imprinting.

PIK3CA, TRIM28

GO:2000657

BP

negative regulation of apolipoprotein binding

Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding.

MAPK3

GO:2000660

BP

negative regulation of interleukin-1-mediated signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway.

IL6, IL1RN, IL1R2, ZNF675

GO:2000661

BP

positive regulation of interleukin-1-mediated signaling pathway

Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway.

IL1R1

GO:2000663

BP

negative regulation of interleukin-5 secretion

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-5 secretion.

TNFRSF21

GO:2000664

BP

positive regulation of interleukin-5 secretion

Any process that activates or increases the frequency, rate or extent of interleukin-5 secretion.

IL17RB

GO:2000666

BP

negative regulation of interleukin-13 secretion

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-13 secretion.

TNFRSF21

GO:2000667

BP

positive regulation of interleukin-13 secretion

Any process that activates or increases the frequency, rate or extent of interleukin-13 secretion.

PAEP, IL17RB

GO:2000669

BP

negative regulation of dendritic cell apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.

GAS6, LILRB1

GO:2000670

BP

positive regulation of dendritic cell apoptotic process

Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.

LYN

GO:2000672

BP

negative regulation of motor neuron apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process.

ZPR1

GO:2000675

BP

negative regulation of type B pancreatic cell apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.

CAST, SRSF6, TCF7L2

GO:2000676

BP

positive regulation of type B pancreatic cell apoptotic process

Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process.

EIF2S1, IL6, HDAC1, CAPN10

GO:2000678

BP

negative regulation of transcription regulatory region DNA binding

Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.

SRI, LHX2, PPARA, ZNF675, HEY1

GO:2000679

BP

positive regulation of transcription regulatory region DNA binding

Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.

KLF4, TGFB1, IGF1, RB1, PARP1, HMGA2, TWIST1, TRIM6

GO:2000681

BP

negative regulation of rubidium ion transport

Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transport.

CAB39

GO:2000682

BP

positive regulation of rubidium ion transport

Any process that activates or increases the frequency, rate or extent of rubidium ion transport.

WNK3

GO:2000685

BP

positive regulation of cellular response to X-ray

Any process that activates or increases the frequency, rate or extent of cellular response to X-ray.

HMGA2

GO:2000687

BP

negative regulation of rubidium ion transmembrane transporter activity

Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transmembrane transporter activity.

CAB39

GO:2000688

BP

positive regulation of rubidium ion transmembrane transporter activity

Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity.

WNK3

GO:2000691

BP

negative regulation of cardiac muscle cell myoblast differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.

PRICKLE1

GO:2000696

BP

regulation of epithelial cell differentiation involved in kidney development

Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development.

PRKX

GO:2000707

BP

positive regulation of dense core granule biogenesis

Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis.

PRKCA

GO:2000724

BP

positive regulation of cardiac vascular smooth muscle cell differentiation

Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.

GPER1

GO:2000726

BP

negative regulation of cardiac muscle cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation.

DKK1, BMP2, SOX6

GO:2000727

BP

positive regulation of cardiac muscle cell differentiation

Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.

GREM1, TGFB1, EFNB2, NRG1, MEF2C

GO:2000736

BP

regulation of stem cell differentiation

Any process that modulates the frequency, rate or extent of stem cell differentiation.

TEAD2

GO:2000737

BP

negative regulation of stem cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.

STAT3, NOTCH1, YAP1, ZFP36L2, JAG1, HES1, TRIM6

GO:2000738

BP

positive regulation of stem cell differentiation

Any process that activates or increases the frequency, rate or extent of stem cell differentiation.

GSK3B, PWP1

GO:2000739

BP

regulation of mesenchymal stem cell differentiation

Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation.

PDGFRA

GO:2000741

BP

positive regulation of mesenchymal stem cell differentiation

Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation.

SOX6, SOX9, LTBP3

GO:2000744

BP

positive regulation of anterior head development

Any process that activates or increases the frequency, rate or extent of anterior head development.

SSBP3

GO:2000751

BP

histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore

Any histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore.

GSG2

GO:2000753

BP

positive regulation of glucosylceramide catabolic process

Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process.

PRKCD

GO:2000755

BP

positive regulation of sphingomyelin catabolic process

Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process.

PRKCD

GO:2000757

BP

negative regulation of peptidyl-lysine acetylation

Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation.

HDAC1, HDAC2, KLF15

GO:2000761

BP

positive regulation of N-terminal peptidyl-lysine acetylation

Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.

SOX4

GO:2000766

BP

negative regulation of cytoplasmic translation

Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.

FMR1, CPEB4, CPEB2, CPEB3, UNK

GO:2000767

BP

positive regulation of cytoplasmic translation

Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.

EEF2

GO:2000768

BP

positive regulation of nephron tubule epithelial cell differentiation

Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.

CD24

GO:2000772

BP

regulation of cellular senescence

Any process that modulates the frequency, rate or extent of cellular senescence.

ARNTL, NUAK1, RSL1D1, BMPR1A, NEK4, PNPT1, NEK6, ZNF277

GO:2000773

BP

negative regulation of cellular senescence

Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.

BCL6, PRKDC, CDK6, TWIST1, BCL2L12

GO:2000774

BP

positive regulation of cellular senescence

Any process that activates or increases the frequency, rate or extent of cellular senescence.

EEF1E1, KRAS, HMGA1, HMGA2, YPEL3, PAWR

GO:2000775

BP

histone H3-S10 phosphorylation involved in chromosome condensation

Any histone H3-S10 phosphorylation that is involved in chromosome condensation.

CCNB1

GO:2000777

BP

positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia

Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.

SIRT2

GO:2000778

BP

positive regulation of interleukin-6 secretion

Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.

IL1B, HMGB1, PAEP, HSPD1, XBP1, F2R, F2RL1, HYAL2, TWIST1, TRPV4, IL1RAP, PYCARD

GO:2000779

BP

regulation of double-strand break repair

Any process that modulates the frequency, rate or extent of double-strand break repair.

DEK

GO:2000780

BP

negative regulation of double-strand break repair

Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair.

UBR5, TWIST1, RNF169, OTUB1

GO:2000781

BP

positive regulation of double-strand break repair

Any process that activates or increases the frequency, rate or extent of double-strand break repair.

FOXM1, SPIDR, SLF2, NUDT16, SLF1

GO:2000785

BP

regulation of autophagosome assembly

Any process that modulates the frequency, rate or extent of autophagosome assembly.

TBC1D12, RAB5A, RAB7A, NPRL3, RAB33A, RAB1B, TBC1D14, PIKFYVE

GO:2000786

BP

positive regulation of autophagosome assembly

Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.

RALB, PIP4K2B, RAB3GAP1, KIAA1324, RAB3GAP2, SH3GLB1

GO:2000791

BP

negative regulation of mesenchymal cell proliferation involved in lung development

Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.

NFIB

GO:2000793

BP

cell proliferation involved in heart valve development

Any cell proliferation that is involved in heart valve development.

TWIST1

GO:2000794

BP

regulation of epithelial cell proliferation involved in lung morphogenesis

Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.

SOX9

GO:2000795

BP

negative regulation of epithelial cell proliferation involved in lung morphogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.

NFIB

GO:2000802

BP

positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation

Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.

TWIST1

GO:2000806

BP

positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled

Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.

SETX

GO:2000807

BP

regulation of synaptic vesicle clustering

Any process that modulates the frequency, rate or extent of synaptic vesicle clustering.

PCDH17

GO:2000808

BP

negative regulation of synaptic vesicle clustering

Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering.

PTEN

GO:2000809

BP

positive regulation of synaptic vesicle clustering

Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering.

CDH2, MAGI2, NLGN1

GO:2000810

BP

regulation of bicellular tight junction assembly

Any process that modulates the frequency, rate or extent of tight junction assembly.

MYO1C, SNAI2, GJA1, PRKACA, PKP2

GO:2000811

BP

negative regulation of anoikis

Any process that stops, prevents or reduces the frequency, rate or extent of anoikis.

SNAI2, ITGB1, ITGA5, BCL2, PIK3CA, NOTCH1, CAV1, TLE1, PTK2, MCL1, NTRK2, PDK4

GO:2000812

BP

regulation of barbed-end actin filament capping

Any process that modulates the frequency, rate or extent of barbed-end actin filament capping.

MTPN

GO:2000813

BP

negative regulation of barbed-end actin filament capping

Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping.

LRRC16A

GO:2000818

BP

negative regulation of myoblast proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation.

MSTN

GO:2000819

BP

regulation of nucleotide-excision repair

Any process that modulates the frequency, rate or extent of nucleotide-excision repair.

CUL4A

GO:2000820

BP

negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation

Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation.

HEY1

GO:2000821

BP

regulation of grooming behavior

Any process that modulates the frequency, rate or extent of grooming behavior.

MC4R, DLG4, NRXN1

GO:2000824

BP

negative regulation of androgen receptor activity

Any process that stops, prevents or reduces the frequency, rate or extent of androgen receptor activity.

HEYL

GO:2000825

BP

positive regulation of androgen receptor activity

Any process that activates or increases the frequency, rate or extent of androgen receptor activity.

BUD31

GO:2000827

BP

mitochondrial RNA surveillance

The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.

SUPV3L1

GO:2000828

BP

regulation of parathyroid hormone secretion

Any process that modulates the frequency, rate or extent of parathyroid hormone secretion.

GNAS, GNAS

GO:2000830

BP

positive regulation of parathyroid hormone secretion

Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion.

FGFR1

GO:2000845

BP

positive regulation of testosterone secretion

Any process that activates or increases the frequency, rate or extent of testosterone secretion.

TMF1

GO:2000850

BP

negative regulation of glucocorticoid secretion

Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion.

CRY1

GO:2000852

BP

regulation of corticosterone secretion

Any process that modulates the frequency, rate or extent of corticosterone secretion.

POMC

GO:2000860

BP

positive regulation of aldosterone secretion

Any process that activates or increases the frequency, rate or extent of aldosterone secretion.

BMP6, C1QTNF1

GO:2000864

BP

regulation of estradiol secretion

Any process that modulates the frequency, rate or extent of estradiol secretion.

KDM5B

GO:2000870

BP

regulation of progesterone secretion

Any process that modulates the frequency, rate or extent of progesterone secretion.

GDF9

GO:2000872

BP

positive regulation of progesterone secretion

Any process that activates or increases the frequency, rate or extent of progesterone secretion.

RETN

GO:2000969

BP

positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Any process that activates or increases the frequency, rate or extent of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity.

ARC

GO:2000973

BP

regulation of pro-B cell differentiation

Any process that modulates the frequency, rate or extent of pro-B cell differentiation.

SOS1, FLCN, FNIP1

GO:2000974

BP

negative regulation of pro-B cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.

NOTCH1, HES1

GO:2000978

BP

negative regulation of forebrain neuron differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation.

HES1

GO:2000979

BP

positive regulation of forebrain neuron differentiation

Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation.

PROX1

GO:2000984

BP

negative regulation of ATP citrate synthase activity

Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity.

CHCHD10, PHPT1

GO:2000987

BP

positive regulation of behavioral fear response

Any process that activates or increases the frequency, rate or extent of behavioral fear response.

PENK, GJA1, MEF2C

GO:2001013

BP

epithelial cell proliferation involved in renal tubule morphogenesis

Any epithelial cell proliferation that is involved in renal tubule morphogenesis.

MTSS1, LGR5, MEF2C, LGR4

GO:2001014

BP

regulation of skeletal muscle cell differentiation

Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.

DDX5, NR1D2, DDX17, UQCC2

GO:2001015

BP

negative regulation of skeletal muscle cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.

S100B, CAPN3

GO:2001016

BP

positive regulation of skeletal muscle cell differentiation

Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.

ARNTL, GPC1, MEF2C

GO:2001020

BP

regulation of response to DNA damage stimulus

Any process that modulates the frequency, rate or extent of response to DNA damage stimulus.

IER3, NEK4, CASP9, MCL1, NPAS2

GO:2001022

BP

positive regulation of response to DNA damage stimulus

Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.

MYC, HMGA2, PRKCD, FMR1, NSMCE4A, BCLAF1

GO:2001023

BP

regulation of response to drug

Any process that modulates the frequency, rate or extent of response to drug.

ADIRF

GO:2001027

BP

negative regulation of endothelial cell chemotaxis

Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis.

THBS1, NOTCH1

GO:2001028

BP

positive regulation of endothelial cell chemotaxis

Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.

HSPB1, MET, SEMA5A, PRKD1, PRKD2

GO:2001032

BP

regulation of double-strand break repair via nonhomologous end joining

Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining.

WHSC1, DEK