Search Geneontologies

Geneontologies

GO ID Ontology GO Term Term Definition Proteins

GO:2000351

BP

regulation of endothelial cell apoptotic process

Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.

TEK

GO:2000352

BP

negative regulation of endothelial cell apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.

KRIT1, FGA, FGB, FGG, SERPINE1, ICAM1, SCG2, TNFAIP3, TEK, MAPK7, SEMA5A, GAS6, ANGPT1, NDNF

GO:2000353

BP

positive regulation of endothelial cell apoptotic process

Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.

FOXO3, THBS1, CD40LG, COL18A1, PRKCI, AKR1C3, ANO6, GPER1, RGCC, CD248

GO:2000354

BP

regulation of ovarian follicle development

Any process that modulates the frequency, rate or extent of ovarian follicle development.

GNRH1

GO:2000355

BP

negative regulation of ovarian follicle development

Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.

AMH

GO:2000360

BP

negative regulation of binding of sperm to zona pellucida

Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.

ZP3

GO:2000366

BP

positive regulation of STAT protein import into nucleus

Any process that activates or increases the frequency, rate or extent of STAT protein import into nucleus.

IL6, LEP, ERBB4

GO:2000368

BP

positive regulation of acrosomal vesicle exocytosis

Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.

ZP3

GO:2000369

BP

regulation of clathrin-dependent endocytosis

Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis.

PIK3CB, TNK2, AAK1

GO:2000370

BP

positive regulation of clathrin-dependent endocytosis

Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.

WASL, DAB2

GO:2000373

BP

positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity

Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.

PLSCR1, HNRNPU, UHRF1

GO:2000376

BP

positive regulation of oxygen metabolic process

Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.

MT3

GO:2000377

BP

regulation of reactive oxygen species metabolic process

Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.

PARK2, TUSC2, ARF4, MPV17, EIF6, FOXM1, FOXO1, CYP1B1, PID1, PINK1

GO:2000378

BP

negative regulation of reactive oxygen species metabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.

PARK2, CRYAB, MYCN, BCL2, G6PD, MT3, BRCA1, PLIN5, BNIP3, HIF1A, SIRT2, PINK1, AATF

GO:2000379

BP

positive regulation of reactive oxygen species metabolic process

Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.

F2, AGT, PDGFB, TP53, THBS1, PDGFRB, NQO2, CD36, GADD45A, TSPO, AGTR1, TGFBR2, CDKN1A, LEP, AKR1C3, XDH, ROMO1, GRB2, RIPK1, MAPK14, DUOXA1, PID1, NOX4

GO:2000386

BP

positive regulation of ovarian follicle development

Any process that activates or increases the frequency, rate or extent of ovarian follicle development.

ZP3

GO:2000388

BP

positive regulation of antral ovarian follicle growth

Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.

ZP3

GO:2000391

BP

positive regulation of neutrophil extravasation

Any process that activates or increases the frequency, rate or extent of neutrophil extravasation.

IL1A, IL1R1, ADAM8

GO:2000393

BP

negative regulation of lamellipodium morphogenesis

Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis.

KANK1, ARPIN

GO:2000394

BP

positive regulation of lamellipodium morphogenesis

Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis.

ENPP2, ARHGEF7, CORO1B, CORO1C

GO:2000402

BP

negative regulation of lymphocyte migration

Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.

WASL

GO:2000405

BP

negative regulation of T cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration.

APOD

GO:2000406

BP

positive regulation of T cell migration

Any process that activates or increases the frequency, rate or extent of T cell migration.

CCL5, CXCL12, CCL20, PYCARD

GO:2000415

BP

positive regulation of fibronectin-dependent thymocyte migration

Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration.

ADAM8

GO:2000418

BP

positive regulation of eosinophil migration

Any process that activates or increases the frequency, rate or extent of eosinophil migration.

ADAM8

GO:2000420

BP

negative regulation of eosinophil extravasation

Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation.

PTGER4

GO:2000425

BP

regulation of apoptotic cell clearance

Any process that modulates the frequency, rate or extent of apoptotic cell clearance.

ITGAV

GO:2000427

BP

positive regulation of apoptotic cell clearance

Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance.

C3, C4A, C4B, CCL2, MFGE8

GO:2000438

BP

negative regulation of monocyte extravasation

Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation.

PLCB1

GO:2000439

BP

positive regulation of monocyte extravasation

Any process that activates or increases the frequency, rate or extent of monocyte extravasation.

PDGFD

GO:2000446

BP

regulation of macrophage migration inhibitory factor signaling pathway

Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.

ANGPT1

GO:2000454

BP

positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation

Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.

FADD

GO:2000458

BP

regulation of astrocyte chemotaxis

Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.

GPR183

GO:2000463

BP

positive regulation of excitatory postsynaptic potential

Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.

PTEN, DLG4, NLGN1, NRXN1, RIMS2

GO:2000465

BP

regulation of glycogen (starch) synthase activity

Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity.

PPP1R3F

GO:2000466

BP

negative regulation of glycogen (starch) synthase activity

Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity.

GSK3B, INPP5K

GO:2000467

BP

positive regulation of glycogen (starch) synthase activity

Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity.

IGF2, ADIPOQ, EPM2AIP1

GO:2000473

BP

positive regulation of hematopoietic stem cell migration

Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.

PTPRC

GO:2000478

BP

positive regulation of metanephric glomerular visceral epithelial cell development

Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.

ADIPOQ

GO:2000479

BP

regulation of cAMP-dependent protein kinase activity

Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity.

MST1, SESN2

GO:2000480

BP

negative regulation of cAMP-dependent protein kinase activity

Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.

PRKAR1A, PRKAR2A, PRKAR2B, PKIA, PKIG

GO:2000481

BP

positive regulation of cAMP-dependent protein kinase activity

Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity.

ATP2B4, ADIPOQ

GO:2000482

BP

regulation of interleukin-8 secretion

Any process that modulates the frequency, rate or extent of interleukin-8 secretion.

CRP

GO:2000483

BP

negative regulation of interleukin-8 secretion

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-8 secretion.

ANXA1, ANXA4, PTPN22

GO:2000484

BP

positive regulation of interleukin-8 secretion

Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.

CD58, F2R, WNT5A, F2RL1, HYAL2, CD244, PYCARD

GO:2000486

BP

negative regulation of glutamine transport

Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport.

LEP

GO:2000490

BP

negative regulation of hepatic stellate cell activation

Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation.

GCLC, CYGB

GO:2000491

BP

positive regulation of hepatic stellate cell activation

Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.

PDGFRB, LEP, RPS6KA1

GO:2000502

BP

negative regulation of natural killer cell chemotaxis

Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis.

CCL2

GO:2000503

BP

positive regulation of natural killer cell chemotaxis

Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis.

CXCL14, CCL3, CCL4, CCL5

GO:2000504

BP

positive regulation of blood vessel remodeling

Any process that activates or increases the frequency, rate or extent of blood vessel remodeling.

TMBIM1

GO:2000505

BP

regulation of energy homeostasis

Any process that modulates the frequency, rate or extent of energy homeostasis.

CD36, LEPR, PRKAA2, FOXO1, NR1D2, BMP8A, NR4A3, PASK

GO:2000506

BP

negative regulation of energy homeostasis

Any process that stops, prevents or reduces the frequency, rate or extent of energy homeostasis.

FLCN, GHRL

GO:2000507

BP

positive regulation of energy homeostasis

Any process that activates or increases the frequency, rate or extent of energy homeostasis.

TRPV4, PPARGC1A, GHRL

GO:2000510

BP

positive regulation of dendritic cell chemotaxis

Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.

CALR, IL12A, C1QBP, GAS6

GO:2000516

BP

positive regulation of CD4-positive, alpha-beta T cell activation

Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.

CD55

GO:2000521

BP

negative regulation of immunological synapse formation

Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation.

LGALS3

GO:2000533

BP

negative regulation of renal albumin absorption

Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption.

GAS6

GO:2000534

BP

positive regulation of renal albumin absorption

Any process that activates or increases the frequency, rate or extent of renal albumin absorption.

ADIPOQ

GO:2000535

BP

regulation of entry of bacterium into host cell

Any process that modulates the frequency, rate or extent of entry of bacterium into host cell.

CXCL8, CAV1, EXOC2, FUCA2, EXOC7

GO:2000536

BP

negative regulation of entry of bacterium into host cell

Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell.

ITGAV

GO:2000541

BP

positive regulation of protein geranylgeranylation

Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation.

MUSK

GO:2000543

BP

positive regulation of gastrulation

Any process that activates or increases the frequency, rate or extent of gastrulation.

OTX2, RACK1, TENM4, OSR1

GO:2000544

BP

regulation of endothelial cell chemotaxis to fibroblast growth factor

Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.

FGF2

GO:2000546

BP

positive regulation of endothelial cell chemotaxis to fibroblast growth factor

Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.

FGF18, FGF2, FGFR1

GO:2000553

BP

positive regulation of T-helper 2 cell cytokine production

Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.

IL6

GO:2000560

BP

positive regulation of CD24 biosynthetic process

Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process.

PLCB1

GO:2000563

BP

positive regulation of CD4-positive, alpha-beta T cell proliferation

Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.

CD55

GO:2000564

BP

regulation of CD8-positive, alpha-beta T cell proliferation

Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.

IRF1

GO:2000566

BP

positive regulation of CD8-positive, alpha-beta T cell proliferation

Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.

HLA-E, CD244

GO:2000568

BP

positive regulation of memory T cell activation

Any process that activates or increases the frequency, rate or extent of memory T cell activation.

TNFSF4

GO:2000570

BP

positive regulation of T-helper 2 cell activation

Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation.

TNFSF4, PRKCQ

GO:2000572

BP

positive regulation of interleukin-4-dependent isotype switching to IgE isotypes

Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.

TNFSF4

GO:2000573

BP

positive regulation of DNA biosynthetic process

Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.

PAK3, MYC, PDGFB, PDGFRB, HGF, PRKD2, RGCC, NOX4

GO:2000574

BP

regulation of microtubule motor activity

Any process that modulates the frequency, rate or extent of microtubule motor activity.

CCDC42B, NDEL1, NDE1

GO:2000584

BP

negative regulation of platelet-derived growth factor receptor-alpha signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.

ADIPOQ

GO:2000587

BP

negative regulation of platelet-derived growth factor receptor-beta signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.

PTPN2

GO:2000590

BP

negative regulation of metanephric mesenchymal cell migration

Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration.

ADIPOQ

GO:2000591

BP

positive regulation of metanephric mesenchymal cell migration

Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration.

PDGFB

GO:2000594

BP

positive regulation of metanephric DCT cell differentiation

Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation.

PAX8

GO:2000601

BP

positive regulation of Arp2/3 complex-mediated actin nucleation

Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.

WASL, CYFIP1, ABI2

GO:2000609

BP

regulation of thyroid hormone generation

Any process that modulates the frequency, rate or extent of thyroid hormone generation.

DUOXA1, DUOXA2

GO:2000611

BP

positive regulation of thyroid hormone generation

Any process that activates or increases the frequency, rate or extent of thyroid hormone generation.

PAX8

GO:2000612

BP

regulation of thyroid-stimulating hormone secretion

Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion.

PAX8

GO:2000615

BP

regulation of histone H3-K9 acetylation

Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation.

CHEK1

GO:2000616

BP

negative regulation of histone H3-K9 acetylation

Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation.

ZNF451

GO:2000617

BP

positive regulation of histone H3-K9 acetylation

Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation.

BRCA1, SMAD4, NAP1L2

GO:2000620

BP

positive regulation of histone H4-K16 acetylation

Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation.

BRCA1

GO:2000623

BP

negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.

SECISBP2

GO:2000627

BP

positive regulation of miRNA catabolic process

Any process that activates or increases the frequency, rate or extent of miRNA catabolic process.

PNPT1

GO:2000628

BP

regulation of miRNA metabolic process

Any process that modulates the frequency, rate or extent of miRNA metabolic process.

KHSRP

GO:2000630

BP

positive regulation of miRNA metabolic process

Any process that activates or increases the frequency, rate or extent of miRNA metabolic process.

NFKB1, RELA

GO:2000632

BP

negative regulation of pre-miRNA processing

Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing.

BCDIN3D

GO:2000637

BP

positive regulation of gene silencing by miRNA

Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA.

ZFP36, STAT3, FXR1, FMR1, PUM1, PUM2, AJUBA, LIMD1

GO:2000641

BP

regulation of early endosome to late endosome transport

Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.

MAPK3, MAPK1, MAP2K2, MAP2K1

GO:2000642

BP

negative regulation of early endosome to late endosome transport

Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport.

SNX3, SNX12

GO:2000643

BP

positive regulation of early endosome to late endosome transport

Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport.

EZR, RDX, DAB2, MTMR2, RAB21

GO:2000645

BP

negative regulation of receptor catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process.

MTMR2

GO:2000647

BP

negative regulation of stem cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.

SNAI2, FBLN1

GO:2000648

BP

positive regulation of stem cell proliferation

Any process that activates or increases the frequency, rate or extent of stem cell proliferation.

KDM1A, PTPRC, EPCAM, HMGA2