GO:2000054

BP

negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification

Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.

SFRP1, SOST

GO:2000055

BP

positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification

Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.

LRP6

GO:2000057

BP

negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.

SFRP5

GO:2000059

BP

negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process.

PSEN1, HFE, PDCL3, TRIM39, SUFU

GO:2000060

BP

positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Any process that activates or increases the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process.

AXIN1, CLU, PTEN, PTK2, FBXO22

GO:2000065

BP

negative regulation of cortisol biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process.

BMP2, DKK3

GO:2000074

BP

regulation of type B pancreatic cell development

Any process that modulates the frequency, rate or extent of pancreatic B cell development.

ARNTL, RHEB

GO:2000077

BP

negative regulation of type B pancreatic cell development

Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.

GSK3B

GO:2000078

BP

positive regulation of type B pancreatic cell development

Any process that activates or increases the frequency, rate or extent of pancreatic B cell development.

BAD

GO:2000080

BP

negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.

SFRP1

GO:2000095

BP

regulation of Wnt signaling pathway, planar cell polarity pathway

Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.

NPHP3, MKS1, DACT1

GO:2000096

BP

positive regulation of Wnt signaling pathway, planar cell polarity pathway

Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.

DAB2, RSPO3

GO:2000097

BP

regulation of smooth muscle cell-matrix adhesion

Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion.

PLAU

GO:2000098

BP

negative regulation of smooth muscle cell-matrix adhesion

Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion.

APOD, SERPINE1

GO:2000105

BP

positive regulation of DNA-dependent DNA replication

Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication.

BMP4, BMP6

GO:2000107

BP

negative regulation of leukocyte apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.

HCLS1, CXCL12, MERTK

GO:2000108

BP

positive regulation of leukocyte apoptotic process

Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process.

NR4A3

GO:2000109

BP

regulation of macrophage apoptotic process

Any process that modulates the frequency, rate or extent of macrophage apoptotic process.

TCP1

GO:2000110

BP

negative regulation of macrophage apoptotic process

Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process.

CCL5, VIMP

GO:2000111

BP

positive regulation of macrophage apoptotic process

Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.

MEF2C

GO:2000114

BP

regulation of establishment of cell polarity

Any process that modulates the frequency, rate or extent of establishment of cell polarity.

KRIT1, ROCK2, CDH5, RACK1, KANK1, RICTOR, RUFY3, KIF20B

GO:2000116

BP

regulation of cysteine-type endopeptidase activity

Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity.

PSMB9, BIRC3

GO:2000117

BP

negative regulation of cysteine-type endopeptidase activity

Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity.

CST3, CST2, MT3, IFI16

GO:2000119

BP

negative regulation of sodium-dependent phosphate transport

Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport.

SFRP4

GO:2000121

BP

regulation of removal of superoxide radicals

Any process that modulates the frequency, rate or extent of removal of superoxide radicals.

DHFR, CD36

GO:2000124

BP

regulation of endocannabinoid signaling pathway

Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway.

MGLL, ABHD6

GO:2000134

BP

negative regulation of G1/S transition of mitotic cell cycle

Any cell cycle regulatory process that prevents the commitment of a cell from G1 to S phase of the mitotic cell cycle.

CTDSP2, CTDSPL, RB1, BCL2, CDKN1A, CDKN2B, SMARCA4, PTEN, PKD2, FHL1, EZH2, KANK2, JADE1, ZNF655, CTDSP1, BRD7, DACT1

GO:2000137

BP

negative regulation of cell proliferation involved in heart morphogenesis

Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis.

BMP4

GO:2000138

BP

positive regulation of cell proliferation involved in heart morphogenesis

Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis.

BMP10, SOX9

GO:2000142

BP

regulation of DNA-templated transcription, initiation

Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.

RRN3

GO:2000143

BP

negative regulation of DNA-templated transcription, initiation

Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.

THRA

GO:2000144

BP

positive regulation of DNA-templated transcription, initiation

Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.

MITF, JUN, FOSL1, CTNNB1, TWIST1, SETX, BCLAF1

GO:2000145

BP

regulation of cell motility

Any process that modulates the frequency, rate or extent of cell motility.

EREG, DAPK3, ROCK2, EGFR, RAF1, ERBB2, ERBB3, BTC, ABL2, CD81, RHOA, CDK6, NRG1, ERBB4, PKN1, PKN2, ARHGAP18, HBEGF, SSX2IP

GO:2000146

BP

negative regulation of cell motility

Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.

SPINT2, FBLN1, CTNNA1, SPOCK3

GO:2000147

BP

positive regulation of cell motility

Any process that activates or increases the frequency, rate or extent of cell motility.

CSF1R, EPCAM, AKT2, TWIST1, SPOCK2, PHPT1

GO:2000156

BP

regulation of retrograde vesicle-mediated transport, Golgi to ER

Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER.

BET1L

GO:2000158

BP

positive regulation of ubiquitin-specific protease activity

Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.

VCP, TANK

GO:2000167

BP

regulation of planar cell polarity pathway involved in neural tube closure

Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.

NPHP3

GO:2000170

BP

positive regulation of peptidyl-cysteine S-nitrosylation

Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.

ACE

GO:2000171

BP

negative regulation of dendrite development

Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.

CARM1

GO:2000172

BP

regulation of branching morphogenesis of a nerve

Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve.

SHOX2, RTN4

GO:2000177

BP

regulation of neural precursor cell proliferation

Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.

FOXO3, NF2, FOXO1, SHCBP1, PTBP2

GO:2000178

BP

negative regulation of neural precursor cell proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.

SPINT2, BTG2, ID2, ILK, RAPGEF1

GO:2000179

BP

positive regulation of neural precursor cell proliferation

Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.

KDM1A, NES, ASCL1, GNG5, INSM1, KIAA1524, PROX1, DLL4, ADGRG1

GO:2000182

BP

regulation of progesterone biosynthetic process

Any process that modulates the frequency, rate or extent of progesterone biosynthetic process.

EGR1

GO:2000184

BP

positive regulation of progesterone biosynthetic process

Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process.

PPARGC1A

GO:2000188

BP

regulation of cholesterol homeostasis

Any process that modulates the frequency, rate or extent of cholesterol homeostasis.

LDLR, NR1D1, RORA, NR1H2, SREBF2, NR1H3, NR1H4

GO:2000189

BP

positive regulation of cholesterol homeostasis

Any process that activates or increases the frequency, rate or extent of cholesterol homeostasis.

NPC1, NR1H3

GO:2000191

BP

regulation of fatty acid transport

Any process that modulates the frequency, rate or extent of fatty acid transport.

NCOR1, REPIN1

GO:2000194

BP

regulation of female gonad development

Any process that modulates the frequency, rate or extent of female gonad development.

NUPR1, INSR

GO:2000195

BP

negative regulation of female gonad development

Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development.

WT1, ZFPM2

GO:2000210

BP

positive regulation of anoikis

Any process that activates or increases the frequency, rate or extent of anoikis.

SIK1, AES, MYBBP1A

GO:2000213

BP

positive regulation of glutamate metabolic process

Any process that activates or increases the frequency, rate or extent of glutamate metabolic process.

NR1H4

GO:2000224

BP

regulation of testosterone biosynthetic process

Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.

AKR1C3

GO:2000227

BP

negative regulation of pancreatic A cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation.

HES1

GO:2000230

BP

negative regulation of pancreatic stellate cell proliferation

Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation.

PPARG

GO:2000233

BP

negative regulation of rRNA processing

Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.

SHQ1, NUDT16

GO:2000249

BP

regulation of actin cytoskeleton reorganization

Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.

RHOD, SEMA3E, DAPK3, TGFB1, CSF1R, PDGFRA, ABL2, ARHGDIA, ARHGDIB, PHPT1, F11R

GO:2000251

BP

positive regulation of actin cytoskeleton reorganization

Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.

HAX1, HCLS1, CDK5, TEK, BAIAP2L1

GO:2000252

BP

negative regulation of feeding behavior

Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.

INS, TRH, MC4R, NPY2R, RETN

GO:2000253

BP

positive regulation of feeding behavior

Any process that activates or increases the frequency, rate or extent of feeding behavior.

AGRP, NR4A3

GO:2000255

BP

negative regulation of male germ cell proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.

PTGDS, PRDX4

GO:2000256

BP

positive regulation of male germ cell proliferation

Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.

CIB1

GO:2000266

BP

regulation of blood coagulation, intrinsic pathway

Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway.

SERPINC1

GO:2000269

BP

regulation of fibroblast apoptotic process

Any process that modulates the frequency, rate or extent of fibroblast apoptotic process.

IER3IP1

GO:2000270

BP

negative regulation of fibroblast apoptotic process

Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.

PIK3CA, PIK3CG, GAS6, SFRP1, CHD8, CFDP1

GO:2000271

BP

positive regulation of fibroblast apoptotic process

Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process.

BCL2L11, STK17B, BTG1, SFRP1

GO:2000272

BP

negative regulation of receptor activity

Any process that stops, prevents or reduces the frequency, rate or extent of receptor activity.

HFE, LYPD1, PCSK9, PPARGC1A

GO:2000273

BP

positive regulation of receptor activity

Any process that activates or increases the frequency, rate or extent of receptor activity.

GREM1, IGF2, ANXA2, ACTN2, CDK5, NCOA2, HFE, PPARGC1B, SRA1, BAZ1B, MED16

GO:2000276

BP

negative regulation of oxidative phosphorylation uncoupler activity

Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity.

PPIF, TWIST1

GO:2000278

BP

regulation of DNA biosynthetic process

Any process that modulates the frequency, rate or extent of DNA biosynthetic process.

CDKN1A, SH2B1

GO:2000279

BP

negative regulation of DNA biosynthetic process

Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.

GJA1, DUSP1, BMPR2, ANKRD1, RGN, ADIPOQ, DACH1

GO:2000286

BP

receptor internalization involved in canonical Wnt signaling pathway

A receptor internalization process that contributes to canonical Wnt signaling pathway.

RAB5A, CAV1

GO:2000288

BP

positive regulation of myoblast proliferation

Any process that activates or increases the frequency, rate or extent of myoblast proliferation.

SOX15, PPARD, PITX2, PAXBP1

GO:2000296

BP

negative regulation of hydrogen peroxide catabolic process

Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process.

HP, MT3

GO:2000297

BP

negative regulation of synapse maturation

Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation.

NFATC4

GO:2000299

BP

negative regulation of Rho-dependent protein serine/threonine kinase activity

Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.

CHORDC1

GO:2000300

BP

regulation of synaptic vesicle exocytosis

Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.

SYN1, RAB5A, RIMS4, RIMS2

GO:2000301

BP

negative regulation of synaptic vesicle exocytosis

Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis.

RAP1A, FMR1

GO:2000302

BP

positive regulation of synaptic vesicle exocytosis

Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.

NLGN1

GO:2000304

BP

positive regulation of ceramide biosynthetic process

Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process.

CYR61, TNF, RACK1, PRKCD, NSMAF

GO:2000309

BP

positive regulation of tumor necrosis factor (ligand) superfamily member 11 production

Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.

ADAM8

GO:2000310

BP

regulation of N-methyl-D-aspartate selective glutamate receptor activity

Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.

DAPK1, DLG4, MEF2C, MAPK8IP2, NLGN1, PPARGC1A

GO:2000311

BP

regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Any process that modulates the frequency, rate or extent of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity.

MEF2C, MAPK8IP2, NLGN1, MINK1, CACNG8

GO:2000312

BP

regulation of kainate selective glutamate receptor activity

Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity.

KLHL24, NETO2

GO:2000318

BP

positive regulation of T-helper 17 type immune response

Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.

IL12RB1, PRKCQ

GO:2000320

BP

negative regulation of T-helper 17 cell differentiation

Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.

FOXP3

GO:2000323

BP

negative regulation of glucocorticoid receptor signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway.

ARNTL, PER1, PHB, CRY1

GO:2000327

BP

positive regulation of ligand-dependent nuclear receptor transcription coactivator activity

Any process that activates or increases the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.

CNOT6

GO:2000330

BP

positive regulation of T-helper 17 cell lineage commitment

Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment.

IL12RB1

GO:2000334

BP

positive regulation of blood microparticle formation

Any process that activates or increases the frequency, rate or extent of blood microparticle formation.

TNF, CD36

GO:2000340

BP

positive regulation of chemokine (C-X-C motif) ligand 1 production

Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.

TIRAP, TRPV4

GO:2000342

BP

negative regulation of chemokine (C-X-C motif) ligand 2 production

Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.

KLF4, MAP2K5

GO:2000343

BP

positive regulation of chemokine (C-X-C motif) ligand 2 production

Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.

TNF, CD74, MIF, TIRAP, HDAC1

GO:2000344

BP

positive regulation of acrosome reaction

Any process that activates or increases the frequency, rate or extent of the acrosome reaction.

ZP3, PLCB1

GO:2000345

BP

regulation of hepatocyte proliferation

Any process that modulates the frequency, rate or extent of hepatocyte proliferation.

SULF2

GO:2000346

BP

negative regulation of hepatocyte proliferation

Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.

CPB2

GO:2000347

BP

positive regulation of hepatocyte proliferation

Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.

XBP1, TNFAIP3

GO:2000348

BP

regulation of CD40 signaling pathway

Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway.

FANCD2

GO:2000349

BP

negative regulation of CD40 signaling pathway

Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway.

TNFAIP3