GO:0016209

MF

antioxidant activity

Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.

HP, APOE, ALB, S100A9, MT3, PRDX2, AAED1, TP53INP1, VIMP, FAM213A

GO:0016212

MF

kynurenine-oxoglutarate transaminase activity

Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.

GOT2

GO:0016213

MF

linoleoyl-CoA desaturase activity

Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O.

FADS2

GO:0016229

MF

steroid dehydrogenase activity

Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.

HSD17B11

GO:0016230

MF

sphingomyelin phosphodiesterase activator activity

Increases the activity of the enzyme sphingomyelin phosphodiesterase.

STX4, NSMAF

GO:0016231

MF

beta-N-acetylglucosaminidase activity

Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.

MGEA5

GO:0016247

MF

channel regulator activity

Modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.

CACNG8

GO:0016248

MF

channel inhibitor activity

Stops, prevents, or reduces the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.

BCL2

GO:0016250

MF

N-sulfoglucosamine sulfohydrolase activity

Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.

SGSH

GO:0016262

MF

protein N-acetylglucosaminyltransferase activity

Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein.

OGT

GO:0016274

MF

protein-arginine N-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.

PRMT3, CARM1, PRMT6, PRMT1

GO:0016278

MF

lysine N-methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue.

SETD9, KMT5A

GO:0016279

MF

protein-lysine N-methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.

EZH2, METTL10, ETFBKMT, SETD6, SETD7, N6AMT2, METTL21A, EHMT2, KMT5A

GO:0016287

MF

glycerone-phosphate O-acyltransferase activity

Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA.

GNPAT

GO:0016289

MF

CoA hydrolase activity

Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.

ACOT8, NUDT7

GO:0016290

MF

palmitoyl-CoA hydrolase activity

Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.

ACOT7, ACOT8, GNPAT, PPT1, THEM4, ACOT4

GO:0016295

MF

myristoyl-[acyl-carrier-protein] hydrolase activity

Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate.

FASN

GO:0016296

MF

palmitoyl-[acyl-carrier-protein] hydrolase activity

Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate.

FASN

GO:0016298

MF

lipase activity

Catalysis of the hydrolysis of a lipid or phospholipid.

LYPLA1, AADAC, LIPA

GO:0016301

MF

kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

CDC7, PIK3CD, CHEK1, FAM20B, RAF1, CCL3, BCR, PRPS2, PKM, CDK2, MAPK3, MAPK1, WEE1, AKT1, CSK, PIK3CA, PIK3CB, MAPK8, CSNK1A1, PIK3CG, GSK3B, CDK7, IRAK1, PLK1, PRPS1, CDK5, DGKZ, PRKD1, RPS6KA2, RPS6KA1, PKN2, CERKL, SGMS1, PIK3C3, SGMS2, MASTL, NEK1, PKMYT1, PINK1, TPK1, TRRAP

GO:0016303

MF

1-phosphatidylinositol-3-kinase activity

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).

PIK3CD, PIK3C2A, FGF18, FGF19, FGF2, FGFR1, FGF7, FGFR2, PIK3R1, FGF9, IRS1, PIK3CA, PIK3CB, PIK3CG, GRB2, PTPN11, GAB1, PIK3C3, FRS2, PIK3R4, KL, IRS2

GO:0016308

MF

1-phosphatidylinositol-4-phosphate 5-kinase activity

Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+).

PIP5K1B, PIP5K1C, PIP4K2B, PIKFYVE

GO:0016309

MF

1-phosphatidylinositol-5-phosphate 4-kinase activity

Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

PIP4K2B

GO:0016312

MF

inositol bisphosphate phosphatase activity

Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate.

INPP5K

GO:0016314

MF

phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity

Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate.

PTEN, INPP5D

GO:0016316

MF

phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity

Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.

INPP4B, INPP4A

GO:0016361

MF

activin receptor activity, type I

Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals.

ACVR1B, ACVR1

GO:0016362

MF

activin receptor activity, type II

Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.

ACVR2B, BMPR2

GO:0016402

MF

pristanoyl-CoA oxidase activity

Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide.

ACOX3, ACOX2

GO:0016403

MF

dimethylargininase activity

Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.

DDAH1, DDAH2

GO:0016404

MF

15-hydroxyprostaglandin dehydrogenase (NAD+) activity

Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.

ABCC4, HPGD

GO:0016407

MF

acetyltransferase activity

Catalysis of the transfer of an acetyl group to an acceptor molecule.

EP300, KAT6B, CREBBP, KAT6A, KAT2B, NAA15

GO:0016409

MF

palmitoyltransferase activity

Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule.

ZDHHC20, ZDHHC17, ZDHHC14, ZDHHC6, ZDHHC7, ZDHHC2, ZDHHC9

GO:0016410

MF

N-acyltransferase activity

Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule.

HRASLS5

GO:0016411

MF

acylglycerol O-acyltransferase activity

Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule.

PNPLA2, PNPLA3

GO:0016422

MF

mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.

METTL14

GO:0016423

MF

tRNA (guanine) methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.

THUMPD3

GO:0016427

MF

tRNA (cytosine) methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine.

METTL2B, METTL2A

GO:0016428

MF

tRNA (cytosine-5-)-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine.

NSUN2

GO:0016430

MF

tRNA (adenine-N6-)-methyltransferase activity

Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine.

TRMO

GO:0016462

MF

pyrophosphatase activity

Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.

ALPL, GMPS, PRUNE2

GO:0016491

MF

oxidoreductase activity

Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

DHRS12, SCD, HSD17B6, KDM1A, FADS1, CREG1, F8, CYP1A1, CYP2E1, CYP3A4, CYP2D6, CYP2C9, CYP3A5, CHM, CHML, GDI1, FDFT1, SNCA, GDI2, SESN3, GSTO1, PIGF, PDIA5, ETFDH, DHRS13, HSDL2, SCD5, ERO1B, ZADH2, OXR1, SUMF1, RDH13, ENOX1, RTN4IP1, KIAA1191, ERO1A, FAR2, DHRS1, HTATIP2, ADI1, C1orf43, GSTO2, SEPN1, OSGIN1, DHRS7

GO:0016494

MF

C-X-C chemokine receptor activity

Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif.

CXCR2, CXCR4

GO:0016501

MF

prostacyclin receptor activity

Combining with prostacyclin (PGI(2)) to initiate a change in cell activity.

PTGDR

GO:0016504

MF

peptidase activator activity

Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.

CLPX, FN1, APP, FBLN1, MMP14, CAV1, PSME4, PCOLCE, PINK1, PCOLCE2

GO:0016505

MF

peptidase activator activity involved in apoptotic process

Increases the activity of a peptidase that is involved in the apoptotic process.

EBAG9, MAL, CTSC

GO:0016508

MF

long-chain-enoyl-CoA hydratase activity

Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms.

HSD17B4

GO:0016509

MF

long-chain-3-hydroxyacyl-CoA dehydrogenase activity

Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.

HADHB, HSD17B12

GO:0016517

MF

interleukin-12 receptor activity

Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

IL12RB1

GO:0016520

MF

growth hormone-releasing hormone receptor activity

Combining with growth hormone-releasing hormone to initiate a change in cell activity.

GHSR

GO:0016524

MF

latrotoxin receptor activity

Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

ADGRL2

GO:0016530

MF

metallochaperone activity

Assists in the delivery of metal ions to target proteins or compartments.

ATOX1

GO:0016531

MF

copper chaperone activity

Assists in the delivery of copper ions to target proteins or compartments.

ATOX1, COX17

GO:0016532

MF

superoxide dismutase copper chaperone activity

A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.

CCS

GO:0016538

MF

cyclin-dependent protein serine/threonine kinase regulator activity

Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.

CCNT1, CCNT2, CCNE2, CDK4, CCNL2, CCNL1

GO:0016594

MF

glycine binding

Interacting selectively and non-covalently with glycine, aminoethanoic acid.

CEP104, GLRB

GO:0016595

MF

glutamate binding

Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid.

CEP104, SLC1A3, GCLC

GO:0016596

MF

thienylcyclohexylpiperidine binding

Interacting selectively and non-covalently with thienylcyclohexylpiperidine.

CEP104

GO:0016597

MF

amino acid binding

Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.

DDAH1, DDAH2, GOT2, ASS1, TH, AGXT, SHMT1, SLC1A3, KARS, TPH2

GO:0016603

MF

glutaminyl-peptide cyclotransferase activity

Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3.

QPCT

GO:0016608

MF

growth hormone-releasing hormone activity

The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland.

GHRH, GHRL

GO:0016614

MF

oxidoreductase activity, acting on CH-OH group of donors

Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

AGPS, XDH, AOX1, DHCR24

GO:0016616

MF

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

CTBP2, ADHFE1, RDH11

GO:0016618

MF

hydroxypyruvate reductase activity

Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+.

GRHPR

GO:0016627

MF

oxidoreductase activity, acting on the CH-CH group of donors

Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

TM7SF2, TECRL

GO:0016628

MF

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.

DHCR24, BDH2

GO:0016641

MF

oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.

LOXL1, LOXL4

GO:0016651

MF

oxidoreductase activity, acting on NAD(P)H

Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

AIFM1, DECR1, MIOX

GO:0016655

MF

oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.

CBR1, AKR1C3, AKR1C2, AKR1C1, DCXR, DHRS4

GO:0016671

MF

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.

TXN, ERO1B, DNAJC10, ERO1A, TXN2

GO:0016679

MF

oxidoreductase activity, acting on diphenols and related substances as donors

Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.

CYP1A1

GO:0016684

MF

oxidoreductase activity, acting on peroxide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.

SESN2

GO:0016701

MF

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.

MIOX

GO:0016702

MF

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.

P4HA2, P4HA1

GO:0016705

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.

PTGIS, OGFOD3, CYP2R1, CYP4V2, CYP2W1

GO:0016706

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.

KDM5A, ALKBH5, KDM7A, MINA, EGLN3, KDM5B

GO:0016709

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

CYP26A1, MICAL2, CYP11A1, CYP2E1, CYP11B1, CYP11B2, MICAL1, CYP26B1

GO:0016711

MF

flavonoid 3'-monooxygenase activity

Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O.

CYP1A1

GO:0016712

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.

CYP2E1, CYP2D6, CYP2A6, CYP19A1, CYP2B6, CYP1B1

GO:0016715

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor.

MOXD1

GO:0016722

MF

oxidoreductase activity, oxidizing metal ions

Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered.

CYBRD1

GO:0016740

MF

transferase activity

Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.

ILVBL, PTDSS1, ILF2, BIRC3, NDUFAF6, IBA57, UHMK1, MOCOS, SCLY, TAOK3, FKRP

GO:0016742

MF

hydroxymethyl-, formyl- and related transferase activity

Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor).

ALDH1L1, ALDH1L2

GO:0016746

MF

transferase activity, transferring acyl groups

Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).

EP300, HGSNAT, KMT2C, TMEM68, LIPT1

GO:0016757

MF

transferase activity, transferring glycosyl groups

Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).

LARGE, EXT1, GTDC1, B3GNTL1, GLT8D1, EXT2, GLT1D1

GO:0016763

MF

transferase activity, transferring pentosyl groups

Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).

TYMP

GO:0016773

MF

phosphotransferase activity, alcohol group as acceptor

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).

FAM20B, G6PC, GK5

GO:0016779

MF

nucleotidyltransferase activity

Catalysis of the transfer of a nucleotidyl group to a reactant.

PAPSS2, EIF2B3, NUDT5

GO:0016780

MF

phosphotransferase activity, for other substituted phosphate groups

Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor).

PIGG

GO:0016783

MF

sulfurtransferase activity

Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).

TRMU

GO:0016784

MF

3-mercaptopyruvate sulfurtransferase activity

Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.

MPST

GO:0016787

MF

hydrolase activity

Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.

NUDT21, PRDX6, GNPDA1, HINT1, FHIT, ENPP2, IDI1, MPPED2, IAH1, ATHL1, MEST, CPSF3L, ABHD17B, ABHD17C, HAGHL, ABHD13, PLPP6, ABHD11, ABHD4, NUDT8, FAHD2A, ABHD14B, TP53RK, CDADC1, HINT2, IDI2, HINT3, ENPP5

GO:0016788

MF

hydrolase activity, acting on ester bonds

Catalysis of the hydrolysis of any ester bond.

PLA2G7, PGAP1, PTER, PGAP3, C11orf54

GO:0016790

MF

thiolester hydrolase activity

Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.

UFSP2, PPT2

GO:0016791

MF

phosphatase activity

Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.

DUSP11, CA3, ACPP, PPP1CC, PPM1F, DUSP3, PPP1CA, PPP1CB, PTPRJ, DUSP8, DUSP5, PTPRO, DUSP18, PXYLP1, DUSP23, DUSP16, DUSP13, PTPN22, DUSP10

GO:0016798

MF

hydrolase activity, acting on glycosyl bonds

Catalysis of the hydrolysis of any glycosyl bond.

MACROD2, ATHL1, MACROD1

GO:0016799

MF

hydrolase activity, hydrolyzing N-glycosyl compounds

Catalysis of the hydrolysis of any N-glycosyl bond.

MAN2A2

GO:0016805

MF

dipeptidase activity

Catalysis of the hydrolysis of a dipeptide.

PM20D2

GO:0016810

MF

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.

DPYSL4, DPYSL3

GO:0016811

MF

hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.

KLK3