GO:0005280

MF

hydrogen:amino acid symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in).

SLC36A1

GO:0005283

MF

sodium:amino acid symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in).

SLC38A1

GO:0005289

MF

high-affinity arginine transmembrane transporter activity

Catalysis of the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

SLC7A2

GO:0005290

MF

L-histidine transmembrane transporter activity

Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid.

SLC38A1

GO:0005292

MF

high-affinity lysine transmembrane transporter activity

Catalysis of the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

SLC7A2

GO:0005308

MF

creatine transmembrane transporter activity

Enables the directed movement of creatine across a membrane. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.

SLC6A8, SLC16A12

GO:0005309

MF

creatine:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in).

SLC6A8

GO:0005310

MF

dicarboxylic acid transmembrane transporter activity

Enables the transfer of dicarboxylic acids from one side of the membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.

SLC25A10

GO:0005313

MF

L-glutamate transmembrane transporter activity

Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid.

SLC25A12, SLC1A3, SLC1A2, SLC25A13

GO:0005314

MF

high-affinity glutamate transmembrane transporter activity

Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + H+(out) = glutamate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

SLC1A3, SLC1A2, SLC1A6

GO:0005315

MF

inorganic phosphate transmembrane transporter activity

Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

SLC20A2, SLC20A1, ANKH

GO:0005316

MF

high-affinity inorganic phosphate:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.

SLC20A1

GO:0005319

MF

lipid transporter activity

Enables the directed movement of lipids into, out of or within a cell, or between cells.

APOE, APOA2, APOD, GM2A, SLCO2A1

GO:0005324

MF

long-chain fatty acid transporter activity

Enables the directed movement of long-chain fatty acids into, out of or within a cell, or between cells. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.

FABP3, ABCD3

GO:0005328

MF

neurotransmitter:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in).

SLC6A1, SLC6A6, SLC6A8, SLC6A14

GO:0005329

MF

dopamine transmembrane transporter activity

Enables the transfer of dopamine from one side of the membrane to the other. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.

SLC22A1, SLC22A3

GO:0005332

MF

gamma-aminobutyric acid:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in).

SLC6A1

GO:0005333

MF

norepinephrine transmembrane transporter activity

Enables the transfer of norepinephrine from one side of the membrane to the other. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.

SLC22A1

GO:0005337

MF

nucleoside transmembrane transporter activity

Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.

SLC29A1

GO:0005338

MF

nucleotide-sugar transmembrane transporter activity

Enables the transfer of a nucleotide-sugar from one side of the membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.

SLC35D2, SLC35E3

GO:0005344

MF

oxygen transporter activity

Enables the directed movement of oxygen into, out of or within a cell, or between cells.

HBB, HBG1, HBA1, CYGB, IPCEF1, NGB

GO:0005345

MF

purine nucleobase transmembrane transporter activity

Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.

AQP9

GO:0005347

MF

ATP transmembrane transporter activity

Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.

SLC25A17

GO:0005350

MF

pyrimidine nucleobase transmembrane transporter activity

Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.

AQP9

GO:0005351

MF

sugar:proton symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + H+(out) = sugar(in) + H+(in).

SLC2A10, SLC35A2, SLC35A1, SLC35A5, SLC2A6, SLC35A3

GO:0005353

MF

fructose transmembrane transporter activity

Enables the transfer of fructose from one side of the membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.

SLC2A5

GO:0005355

MF

glucose transmembrane transporter activity

Enables the transfer of the hexose monosaccharide glucose from one side of the membrane to the other.

SLC2A10, PPBP, SLC2A1, SLC2A3, SLC2A4, SLC2A5, MFSD4B, SLC2A14, SLC2A6

GO:0005369

MF

taurine:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in).

SLC6A6

GO:0005372

MF

water transmembrane transporter activity

Enables the directed movement of water (H2O) from one side of a membrane to the other.

AQP9, AQP2, SLC14A1

GO:0005375

MF

copper ion transmembrane transporter activity

Catalysis of the transfer of copper (Cu) ions from one side of a membrane to the other.

ATOX1, SLC31A1, SLC31A2, SLC11A2

GO:0005381

MF

iron ion transmembrane transporter activity

Catalysis of the transfer of iron (Fe) ions from one side of a membrane to the other.

SLC11A2, TTYH1, SLC40A1

GO:0005384

MF

manganese ion transmembrane transporter activity

Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other.

ZP3, SLC11A1, SLC11A2

GO:0005385

MF

zinc ion transmembrane transporter activity

Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.

SLC39A6, SLC39A14, SLC39A4, SLC30A8, SLC39A8, SLC39A10, SLC30A1

GO:0005388

MF

calcium-transporting ATPase activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).

ATP2A2, ATP2B1, ATP2B4, ATP2C1

GO:0005391

MF

sodium:potassium-exchanging ATPase activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).

ATP1B1, ATP1A2, ATP12A, ATP1B3

GO:0005415

MF

nucleoside:sodium symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in).

SLC28A3

GO:0005427

MF

proton-dependent oligopeptide secondary active transmembrane transporter activity

Catalysis of the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.

CDH17

GO:0005432

MF

calcium:sodium antiporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).

SLC3A2

GO:0005436

MF

sodium:phosphate symporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).

SLC20A2, SLC20A1

GO:0005451

MF

monovalent cation:proton antiporter activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out).

SLC47A1

GO:0005452

MF

inorganic anion exchanger activity

Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out).

SLC4A2, SLC4A8, SLC4A4

GO:0005456

MF

CMP-N-acetylneuraminate transmembrane transporter activity

Enables the transfer of a CMP-N-acetylneuraminate from one side of the membrane to the other.

SLC35A1

GO:0005459

MF

UDP-galactose transmembrane transporter activity

Catalysis of the transfer of a UDP-galactose from one side of the membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.

SLC35A2

GO:0005461

MF

UDP-glucuronic acid transmembrane transporter activity

Catalysis of the transfer of a UDP-glucuronic acid from one side of the membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.

SLC35D1

GO:0005462

MF

UDP-N-acetylglucosamine transmembrane transporter activity

Enables the transfer of a UDP-N-acetylglucosamine from one side of the membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.

SLC35A3

GO:0005477

MF

pyruvate secondary active transmembrane transporter activity

Catalysis of the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.

SLC16A7

GO:0005483

MF

soluble NSF attachment protein activity

Interacting selectively and non-covalently with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.

NAPB

GO:0005484

MF

SNAP receptor activity

Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.

SNAP23, GOSR2, STX7, STX6, VAMP4, SEC22B, STX11, SNAP29, STX2, VAMP7, SNAP25, VAMP2, STX4, STX3, VAMP3, SEC22A, BET1L, VTI1B

GO:0005487

MF

nucleocytoplasmic transporter activity

Enables the directed movement of substances between the nucleus and the cytoplasm of a cell.

XPO1, TPR, NUP62, NUP153, NUP107, NUP160, NUP35, NUP58, UPF3A, NUP62CL, RBM22, NXF1

GO:0005496

MF

steroid binding

Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.

PGRMC2, ESR1, NR3C1, SHBG, PGR, CYP3A4, CYP21A2, AR, ESRRA, HSD11B2, PAQR8, ESR2, GPER1, PAQR5

GO:0005497

MF

androgen binding

Interacting selectively and non-covalently with any androgen, male sex hormones.

ALDH1A1, SHBG, AR, TSPO

GO:0005499

MF

vitamin D binding

Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).

GC, KL

GO:0005501

MF

retinoid binding

Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.

RBP1, PTGDS

GO:0005504

MF

fatty acid binding

Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.

NDUFAB1, APOC1, PMP2, ALB, FABP4, NME2, PTGDS, FABP5

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

PLOD2, SCD, P4HA2, CYP27B1, CYP26A1, SC5D, ETHE1, CH25H, FTL, FTH1, CYP1A1, CYP17A1, CYP11A1, CYP2E1, MFI2, CYP3A4, CYP21A2, ALOX5, FDX1, CYP2D6, CYP2A6, CYP19A1, CYP2C9, P4HA1, CYP11B1, ALOX15, CYP11B2, CYP2B6, CYP3A5, CYP3A7, CALR, NOS3, XDH, ABCE1, HBB, HBG1, HBA1, LCN2, PLOD1, AOX1, MSMO1, PTGIS, CYP1B1, CYP51A1, JMJD6, OGFOD3, CYP2R1, KDM7A, CYP4V2, FA2H, CYP2U1, SCD5, MINA, P3H2, TPH2, CYP2W1, CYGB, ACO2, ADI1, EGLN3, CYP3A43, CYP26B1, NFU1, CYP8B1

GO:0005507

MF

copper ion binding

Interacting selectively and non-covalently with copper (Cu) ions.

ATOX1, CCS, AOC2, F8, IL1A, ALB, ANG, PRNP, TP53, SOD3, F5, TYR, PAM, MT3, LOX, GPC1, SNCA, LOXL1, COX17, AOC3, MOXD1, COMMD1, LOXL4, P2RX4, S100A13, HEPH, METTL17, PRND, LOXL2, COX11

GO:0005509

MF

calcium ion binding

Interacting selectively and non-covalently with calcium ions (Ca2+).

ESYT2, CIB4, MASP2, MATN2, EML1, NDUFAB1, NCAN, PRRG1, PCDH17, CLGN, PLSCR1, CETN3, DHH, ACTN4, CALU, EDIL3, NOL3, EFCAB14, RAB11FIP3, PDCD6, SLC25A12, SLIT2, CLSTN1, LETM1, GUCA1C, EFEMP2, F2, C1R, LDLR, CRP, APCS, BGLAP, MMP1, ANXA1, S100B, S100A8, CLEC3B, S100A9, S100A6, ANXA2, THBS1, ANXA6, MGP, ANXA5, MMP10, SPARC, ANXA4, C1S, HSPA5, MBL2, ANXA3, ACTN1, MYL4, BMP1, VCAN, TPT1, LCP1, PRKCSH, NID1, PLA2G2A, HSP90B1, MYL6B, ARSA, ATP2A2, PAM, CDH2, MYL12A, CAPN3, SYT1, ENPP1, CALB2, MMP8, FBLN1, MMP11, MYL9, S100P, S100A4, PON1, CALR, CANX, S100A2, SRI, S100A7, S100A11, CDH5, MAN1A1, PRSS3, THBS4, FBN1, FBN2, ACTN2, HPCAL1, SNCA, PLA2G5, EPS15, GPD2, NOTCH1, IQGAP1, PLA2G4A, CD97, COMP, MMP14, ANXA11, PLCD1, MMP15, MMP16, CDH6, CDH11, CDH12, CDH13, CDH15, TPD52, MYL6, S100A10, NCALD, CALM2, NCS1, TPM4, ADAM8, JAG1, NUCB2, DLK1, CRB1, FBLN2, VLDLR, HSPG2, LRP2, MYL7, MYL5, DSC2, NUCB1, DST, NOTCH2, PPP2R3A, PCDH1, PPP3CA, TBC1D8B, ASPH, EFEMP1, FSTL1, CDH17, CBLB, MMRN1, PKD2, ENPP2, NID2, DAG1, DSG2, ADGRE1, RCN2, GAS6, SPARCL1, FAT1, ITPR2, ITPR3, ITPR1, PLS1, MELK, LTBP1, RCN1, RYR3, RGN, ITSN1, CACNA1E, AOC3, PGS1, GNPTAB, EYS, EFCAB2, TBC1D9B, MCTP1, CRELD2, CCBE1, PAMR1, TBC1D9, FBN3, LPCAT2, RASGRP2, NOTCH2NL, SPATA21, NECAB2, S100A7A, C2CD5, SULF2, SULF1, SCUBE1, SCUBE3, FAM20C, MICU2, RASEF, NIN, EFCAB3, USP32, REPS2, DNER, MCFD2, PCDH19, SYTL5, FAT3, STAB2, GPR98, TTN, SPOCK2, EDEM1, RYR2, CCDC47, FKBP10, EFHD2, SYTL4, REPS1, VWCE, S100A16, CALML4, PPP3R2, NECAB3, NOX5, NELL2, MMP19, S100A13, CHP1, CIB1, EGFL8, SPOCK3, AIF1L, SDF4, EFCAB11, SLC25A23, CDHR2, PCDH11Y, PLA2G12A, EDEM3, PCDHAC1, EHD4, TTYH1, SMOC2, CLSTN2, EFCAB1, ADGRL3, PCDH9, SLC24A3, SYTL2, PCDH18, CD248, MMP25, CD93, PLCB1, CRTAC1, MAN1C1, DLL4, DUOX2, DUOX1, PLSCR4, LTBP3, KCNIP2, FKBP14, STAB1, CELSR3, ITSN2, EHD3, SEPN1, DSPP, STIM2, PCDH10, ANXA10, CDH22, SLC25A13, MAN1B1, NRXN1, HEG1, PADI4, HPCAL4, EPDR1, GUCA1B, PCDHGC3, PCDHA7, PCDHA6, PCDHA4, PCDHA12, RPH3AL, MACF1, MYO5A, PCDHB9, PCDHB3, PCDHB14, PCDHA9, PCDHA8, PCDHA5, PCDHA3, PCDHA2, PCDHA13, PCDHA11, PCDHA10, PCDHA1, PCDHAC2, MMP24, FKBP7, PCLO

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

UBA6, MED19, CIB4, UBE2QL1, ELOVL7, SH3PXD2B, ZC3H12D, VPS37C, CNOT1, UNC119B, WASH1, NEURL1B, STRA13, BBIP1, MIF4GD, FAM195B, AGPS, UBXN8, DDX39A, ACOT7, MYO1C, SNAP23, HAX1, EYA2, AIP, MASP2, RAB27B, TLR4, APBB1, LGALS8, RNF103, ATOX1, SUPT5H, DFFA, HIP1, CLIC1, WWP2, CDC7, ARNTL, PIK3CD, WASL, FOXN3, IPO5, IGF2BP3, PLK4, MEIS1, EXOC5, NR5A2, NDUFA4, BIN1, KPNA3, KRIT1, SDCBP, NOP56, DDX3X, PEX12, KPNA4, TRIM38, PPP6C, FBP2, UBE2C, ACACB, DLGAP1, PLPP3, ARID1A, BHLHE40, SOCS2, CDK2AP1, SOCS3, SOCS6, TRAFD1, DYNC1I1, COPE, CTDSP2, CCS, GOSR2, TOR1A, ADAM10, ENC1, ITGB1BP1, MAP2K7, ACOT8, PDCD5, CHEK1, TPP1, NDC80, TNPO2, MSTN, TSPAN4, IRF6, TAX1BP3, PCDH17, TIMM23, CASK, EREG, AURKA, RAB29, PPP1R12A, XPO1, PIP5K1B, U2SURP, ANKRD28, SMAD7, FYB, NPC1, ANGPT2, SCAMP1, SCAMP2, KPNA5, ARPC2, ARPC3, MDM4, POLR1C, PLSCR1, AXIN1, CETN3, UBD, GSTA4, NPHP1, FANCG, OGT, GRM6, SIVA1, PMM2, INPP4B, MID1, HMGB3, GPR37, HDAC3, BIRC5, STX7, TOX3, FOXP2, TLR3, MAGEB4, INSIG1, NUPL2, CFLAR, SOCS1, MAFG, ZSCAN9, DHX15, ASAP2, ZBTB24, PSMD3, RBFOX2, SIAH2, ZNHIT1, MAP3K13, DAPK3, TGFB1I1, AP5Z1, CTIF, MAP3K7, DHH, RIPK2, HOXA3, PRPF3, COCH, CBFA2T2, PPIH, OIP5, RAD51C, MED7, ATP8B1, BCL2L11, FOXO3, SPRY2, SPRY1, CHMP2A, TSPAN6, PLRG1, PRC1, ZNF207, BUB1, BUB3, ACTN4, TRIAP1, TRAF3IP2, STX6, SGTA, SSNA1, SLC25A17, NUDT21, C21orf2, NRDC, CALU, AHCYL1, ORC5, TYROBP, PDE6D, RAD21, PPP1R12B, BNIP3L, PARK2, SMARCA5, SPAG9, KIF5C, NUAK1, TRAK2, OPA1, ZEB2, PIP5K1C, KIF1B, KDM1A, FZD6, PPL, BRINP1, PLXNC1, SNX3, SORBS3, GMDS, CCNT1, GREM1, BUB1B, EIF4E2, CCNT2, TLR2, TSPAN2, EXOC3, RAD1, REV3L, JAK2, PRMT3, SRPX2, LPXN, CTNND1, SLC19A2, PFKFB2, PQBP1, DKC1, TRIM13, EDF1, BRD4, RAMP1, RAMP3, TBL1X, NBN, NOL3, MITF, ADAM23, LDB3, ROCK2, MFAP3L, ATG13, OBSL1, ZC3H11A, RAB11FIP3, SOCS5, CNOT3, SIN3B, DNAJB6, LRP5, GADD45B, NDUFS2, ZPR1, USP12, SEMA7A, PDCD6, ATP6V1G1, VPS4B, MPDU1, ZNF217, H2AFY, FLNB, NCOR1, VAMP4, PEX14, ULK1, TULP3, SEC22B, PRPF40A, TACC1, POLQ, VPS26A, ERN1, LGR5, PSIP1, SRSF10, GMNN, CLN5, HSBP1, KHDRBS3, TADA3, BANF1, STX11, PRKRA, LRP6, USP2, OFD1, PPM1B, ADAP1, UTP20, RP2, WDHD1, RAD51D, BCAR3, POP7, PSMD10, TRAPPC6A, STAM2, TUSC2, RASSF9, FLOT1, CLPX, NEBL, RNF8, CIAO1, SLC22A5, PDE9A, SRP72, URI1, USP1, TPPP, SLIT2, ATG12, TOX4, SEC24D, SUPT7L, FCHSD2, UBXN7, ERLIN2, DKK1, GLS, RHOBTB3, TRIM37, SEC31A, CLSTN1, CEP152, HEXIM1, CCNB2, UBR5, FSBP, MFN2, IKBKAP, OAZ2, CSPG5, LETM1, SNX4, ZWINT, LUC7L3, KIF20A, KIF4A, MBD4, GADD45G, TNKS, VAPB, SNAPIN, SMC2, FARS2, ZBTB7A, BMP10, CD2BP2, PARN, PSMG1, ABCA1, TDP2, POLR1A, PCNT, YEATS4, CNOT4, STAMBP, NFATC1, EYA4, APBB3, SNAP29, FGF19, LSM8, WIZ, STAU1, MAP4K4, AIFM1, CLIC3, LATS1, DDAH2, CBX7, EFEMP2, MBD3, PTTG1, BCL10, NDUFB10, ZBED1, PEX11B, ACTL6A, CCNE2, WHSC1, LDHA, F8, EGFR, F2, HP, PLG, PLAU, PLAT, ADA, CA2, SPINK1, SERPINC1, SERPINA1, SERPINA3, AGT, A2M, C3, TIMP1, CST3, KNG1, FOS, MYC, PDGFB, LDLR, TGFA, TGFB1, NGF, PRL, GH1, INS, IGF2, TNF, IL1A, CD4, COL1A1, COL3A1, CRYAB, LMNA, APOA1, APOE, APOA2, FGA, FGB, FGG, CRP, APOH, FN1, RBP4, TTR, ALB, TFRC, TF, FTL, FTH1, MT2A, ESR1, ANG, SLPI, VTN, HMGCR, RAF1, ANXA1, PDGFA, APOB, NR3C1, MYCN, KRT1, S100B, VWF, GAPDH, ERBB2, NTRK1, TP53, CYBB, GNAI2, GYPC, IGF1, ATP1B1, APP, APOD, ITGB3, ITGB2, S100A8, INHA, SERPINE1, SLC25A5, SERPINA5, SERPING1, CFI, ISG15, ALPL, EIF2S1, IL6, ICAM1, RPLP1, RPLP0, SCG5, JUN, FABP3, SSB, ITGB1, PRKCB, KRT18, KRT8, INSR, FYN, RB1, PGR, PTMA, CDK1, S100A9, S100A6, EIF4E, ENO1, NPM1, TPM3, ITGAV, LPL, SERPINE2, TH, LDHB, P4HB, KLK3, ANXA2, TUBB, ADRB2, DCN, PSAP, CTSL, PFN1, EPRS, CTSB, HSP90AA1, HNRNPC, UQCRH, LYN, ERCC1, THBS1, IGF1R, COL1A2, ANXA6, CD55, SLC3A2, HSP90AB1, SOD3, MME, INHBA, MGP, CD14, PTPRC, MET, MFI2, ADRB1, CFH, ITGA5, VIM, KRT19, KRT7, GNAI3, KRT16, RPSA, IL6R, SNRPA, FGF2, HOXB5, GSTP1, CST2, SNRPC, CD48, LGALS1, HMGB1, PAEP, FBP1, SPARC, INHBB, WNT2, HMOX1, PDGFRB, HNRNPA1, SNRPA1, CTSH, FGR, PARP1, POLA1, ALOX5, ALDOC, H2AFZ, HIST1H2AG, FBXO45, UBC, TRAPPC2, HSPA1A, HSPA1B, GLI2, GLI3, RAP2A, SRGN, CXCL8, CCL3, MYBL2, AR, RRAS, HIST1H1E, BCL2, SPP1, DLAT, NR2F1, TXN, COX5B, MAPT, PRKAR1A, KIT, CD28, HSPD1, THRA, CLU, GHR, IRF1, HSPA5, EGR2, SLC2A1, PDHB, ITGAM, PYGB, PYGM, MBL2, RALA, RALB, LAMP1, FGFR1, TOP1, TOP2A, VDR, ESRRA, PC, DMD, SFTPC, IGF2R, CDK4, PRPS2, ODC1, PCNA, SLC25A4, F5, TPR, CKB, FCGR1A, BMP2, BMP4, BCKDHA, SKI, ACTN1, XRCC5, UNG, IFITM1, GP1BB, CCL4, TDGF1, LAMP2, RNH1, CCL5, CFTR, EEF2, PDIA4, P4HA1, TPT1, GYS1, PRKAR2A, ADRB3, GTF2F2, SELL, MIF, HGF, HCLS1, DRD2, PKM, HSP90B1, CCNB1, MYL6B, SLC2A4, SNRPB, TYR, IDE, IL1R1, MMP9, POU2F1, HNRNPL, DARS, ETS1, JUP, ETS2, PVR, GSPT1, ARSA, EZR, FOSL1, FOSL2, VAV1, AREG, CD46, NME1, VEGFA, HIVEP1, RPS2, CHN1, TCF4, ST6GAL1, TCF3, DSP, MUC1, ALOX15, H2AFX, PFKFB1, ITGB4, CREB1, PDGFRA, PECAM1, HIST1H1C, EPCAM, SELE, ATP2A2, CD36, PLCG2, ZNF20, ZNF24, HMGA1, TMEM11, IFNAR1, PRKCA, JUNB, ITGA2, GJA1, UBTF, JUND, TAL1, ATF7, PRKACA, DES, CEBPB, PTPN2, DDX5, PFKL, LGALS3, IGFBP3, PSMC3, TCP1, ERCC2, RPL35A, ITGB5, ARF4, ADRA2B, RPL7, EGR1, SON, RPL17, RCC1, SDC1, ATF1, ATF3, ATF4, ATF6, PAM, EPOR, CD58, POLR2E, CD53, ELK1, TNNI3, WT1, NFKB1, NCF2, FST, ATP2B1, CD33, CCNA2, TNFRSF1B, RAB3B, RAB5A, NR1D1, MSH3, PSMB1, ITGAX, BCL3, MAK, HNF1A, EFNA1, RASA1, MAL, FLNA, AGXT, SYT1, TNFAIP3, SAT1, ZP3, FGFR2, ERBB3, SDHB, CD9, BCKDHB, TGM2, OSBP, IL10, SCP2, UBA1, NME2, ENPP1, GAL, HNRNPA2B1, NR4A1, CA4, MRC1, XPA, ITGA6, SFPQ, TUBG1, PPIB, ANOS1, JAK1, PTPRB, PTPRD, SP100, AHCY, CFL1, ATP2B4, FSHR, IL32, IL4R, NR2F2, GADD45A, EEF1B2, IGFBP5, POLR2A, CDK2, APC, CD24, ADRA1D, F2R, MCM3, NFYB, AZGP1, BRD2, FAS, YY1, DNAJB1, MT3, PSMA1, PSMA2, PSMA3, PSMA4, LMO2, S100P, ITGA3, PTX3, CTNNA2, DNMT1, RPL13, S100A4, HMGB2, PTBP1, TARS, ZFP36, PLN, KLRC1, CD27, MST1, ACVR2A, MAPK3, G0S2, DPP4, ARNT, RPL10, CALR, CANX, IL1R2, PIK3R1, PSMB5, GSTM2, ABCD3, LOX, NDUFS1, POLD1, SMARCA1, MAPK1, MZF1, RXRB, RBL1, GRN, PTPRM, S100A2, CTGF, EPHA3, KDM5A, IL12A, CASP1, NOS3, CD40LG, PBLD, PRDX6, ECHS1, PEBP1, PDIA3, PPP2R1A, PPP2R1B, CDC27, CCND2, CCND3, CDC25A, PPIF, HLA-A, AVPR2, LRPAP1, AGTR1, CLIP1, SRI, POLR2B, SDHA, CORO1A, GDI1, S100A7, MAT2A, PRKAR2B, RRM2, SDC4, TIA1, DNAJA1, AKT1, AKT2, HNRNPH3, HNRNPH1, YWHAB, SFN, FCGR2B, CCKBR, OTX2, MC4R, DCTD, GBP1, GTF2H1, STX2, CTH, CDH5, CKS2, HIST1H2BB, TTK, MCM4, MCM5, MCM7, SDC2, SHMT1, HSPA4, GRK5, PRSS3, BTC, USP6, CA8, CTNNA1, CTNNB1, PHB, NF2, RDX, RPA3, RFC4, RFC2, RPL22, GTF2F1, ADM, PTGS2, RORA, PTGER4, THBS4, CBS, FBN1, FBN2, IRS1, AGL, MYH9, ACTN2, BSG, TIMP3, FUS, DDIT3, AHR, FLT4, PSMC2, TRIM23, MAP2K2, RPL4, PPP1CC, BMPR1A, ACVR1B, TGFBR1, LTBR, SERPINB5, SERPINF1, SREBF1, SCNN1A, SRP14, TGFBR2, NUP62, PPARG, HPCAL1, ZEB1, PIGA, TALDO1, SNCA, RBMX, BRCA1, COIL, CDKN1A, FEN1, CAPG, IL6ST, CCT6A, PBX1, MLH1, STAT3, RFC5, RFC3, PMEL, CCNF, EIF2S3, ID1, ETV5, BCL6, RGS2, BUD31, UBA7, PPP1R2, CSK, MAP3K8, ADCYAP1R1, PRKCI, STAT5A, SKIV2L2, PIK3CA, PIK3CB, EPS15, RPS27, ABL2, NCAPD3, LIFR, LRPPRC, CDKN2B, CDKN2C, NSG1, HTT, ECE1, GDF5, CTSK, MATR3, MSH2, SYK, PSMC4, GATA4, NKX2-1, PPIC, CBX5, MAPK8, MAPK9, MKI67, RANGAP1, RECQL, NOP2, ATRX, CRKL, NSF, CDKN1B, NOTCH1, IER3, BRCC3, RPL5, RPL21, RPL28, RPS9, RPS5, RPS10, MAP1B, YAP1, IQGAP1, EIF1AX, ZFP36L2, MTNR1A, ATP5O, LIMS1, NPBWR1, PREP, GLRB, LEPR, SOX9, CD151, IFNAR2, NRIP1, NMU, CSNK1A1, CSNK1D, PIK3CG, CD97, TRPC1, MAPKAPK2, SLC11A2, FASN, CDK8, DHPS, CCT3, CDC34, CENPA, CENPF, SRP9, UBE2A, PPM1F, HOXA1, CSNK1E, ARL4D, PSMB3, MCM2, COMP, TMED10, RBM25, CLK2, VEGFB, PSEN1, NUP153, RANBP2, PSEN2, TSC2, GSK3B, SEPHS1, CDKN1C, MRE11A, AGTR2, GNAQ, MEOX1, MMP14, GDI2, EMD, SERPINB9, PDLIM4, MXI1, ASCL1, TNFSF10, KNTC1, PPT1, CCT8, ATP1A2, ANXA11, PAPOLA, FXR1, RAB5C, RAB7A, RAB9A, RAB27A, SCNN1G, DAP3, ZNF83, DNA2, SMARCA2, SMARCA4, BCAP31, BRCA2, IRAK1, CAV2, PSMD7, STAT5B, USP11, CLCN3, VAMP7, PRKX, NR0B1, NEK2, CCNG1, HNRNPA3, HNRNPM, KPNA2, KPNA1, POLR2J, MAP2K6, ARHGDIA, ARHGDIB, AGFG1, STAT2, GTF2A1, GTF2A2, MSH6, ZNF136, RBM5, EFNA4, MRPL12, NDST1, HMGA2, PLK1, DAPK1, CEBPG, RABGGTB, AP2S1, TTC3, PLA2G16, IST1, POLG, BLM, RARS, HIRA, ATXN3, ATXN1, ATN1, TERF1, OAZ1, YARS, PRKAG1, PRKAA2, RAD23A, RAD23B, EPHB4, EPHB1, EPHA4, GAS1, EMP1, EMP2, EMP3, EIF5, GEM, RRAD, NR1H2, CSE1L, VCP, HADHB, F2RL1, MLLT10, NAP1L1, CASP9, CASP6, CDH15, FOXG1, TPD52, SEC13, SNU13, GFER, HNRNPH2, SUMO3, EIF3B, BID, POLE2, AP1S2, HDAC4, EIF6, CTBP2, PEX3, SYNJ2BP, GEMIN4, KLF3, NUP107, SESN2, FOXL2, ANTXR2, ADAMTS12, TIRAP, ARPC4, CD81, PTEN, PPP4C, GABARAPL2, ACTB, RAC3, EIF4A1, SNAP25, PRPS1, SHFM1, S100A10, CDC42, DSTN, SRP54, RAB2A, RAB5B, CKS1B, CXCR4, UBE2D3, UBE2M, ABCE1, RPS3A, RPL26, PSME3, RPL15, ATP6V0D1, RPL37A, RHOA, NCALD, HSPE1, SEC61A1, STXBP1, B2M, TGFB2, NPC2, PKIA, SUMO2, DCAF7, LMO4, NUTF2, USP46, RPS7, PPP1CA, PPP1CB, CALM2, NCS1, PSMC1, RPS15A, UBE2H, YWHAE, RPS14, RPS18, RPS13, SNRPF, LSM3, LSM6, SNRPD1, SNRPD2, SNRPD3, BTG1, TMSB4X, PSMC6, RPL7A, RAB11A, PPP2CB, RPL23A, RPS6, HIST1H4A, RAB1A, RAP1A, RPS25, RPS26, RBX1, GNB2, RPL30, RPL31, RPL10A, RPL11, PPIA, RPS27A, UBA52, GRB2, TRA2B, RAC1, AP2B1, VAMP2, GNAI1, YWHAZ, UBE2B, SNRPN, DYNLL1, DYNLT1, SKP1, EIF5A, RACK1, ACTG1, UBE2I, YBX1, TPM4, EEF1A1, TUBA1B, TUBA4A, HIST1H3D, HBB, HBA1, CXADR, IGBP1, ADAM8, RPP30, GTF2I, DLG4, PIP4K2B, SRPK2, CCT2, JAG1, PRKDC, ADAM17, BLOC1S1, BTG2, ELF3, NTHL1, MAP1A, CRADD, ADARB1, MT1H, MT1X, GPSM2, SLC7A9, SARNP, HTRA3, RPL24, RPL36A, CBX1, SMAD3, ARF1, ARF5, ERH, RPL19, H3F3A, GNAS, TNFAIP6, SHC2, DAB2, VLDLR, HSPG2, PKD1, LRP2, XIAP, FOXO4, RBM3, CYCS, MPP1, GTF2B, CDK6, CDK5, CDK16, PURA, HSF1, REEP5, HNRNPU, IRF9, MDM2, SPTBN1, E2F1, SET, SRSF2, RUNX1, PMP22, FABP5, ANK2, IL1RL1, DR1, MC2R, XPC, EWSR1, POU5F1, COL4A3, OCRL, ROR1, MEF2A, CENPE, KIF23, ID2, APBA1, SP3, DSC2, ID3, RPL18A, MAP2K1, TEK, FKBP4, GUCY2D, CREB5, DST, HHEX, GNA12, CAV1, TGFBR3, PLAUR, COL10A1, RELA, NOTCH2, TLE1, TLE3, PRKCQ, ACVR1, AKR1C1, REL, CD164, YWHAH, PTK2, LIPE, ZBTB16, SRSF11, PRKCD, RNASEL, DUSP2, PTPN11, PPP2R3A, EXOSC9, MEF2C, TYRO3, APLP2, SULT2A1, RING1, RAD51, PAX8, FMR1, PRDX1, SOX4, C1QBP, COL16A1, TJP1, ZFP36L1, KHDRBS1, BAX, MCL1, PPARA, SOS1, SOS2, TNK2, SRSF1, FOXM1, AES, PPP3CA, IL10RB, DDR1, GOLGA2, CD47, PPID, SSRP1, ZNF844, DMPK, RBBP4, NCBP1, KCNA1, EP300, AHNAK, ARL16, HSPA14, AP1B1, CPSF1, BST2, NUP160, SREBF2, ARHGEF5, FOXO1, TBL3, KCNMA1, ASPH, TFCP2, AKAP13, EFEMP1, KCNH2, TROAP, CDC20, FSTL1, STX4, MERTK, GRIN2A, HYAL2, TRIM26, ILF2, ILF3, PTPRJ, EPS8, FOXC1, ANK3, DLG1, TAF10, MYO1E, BNIP3, CSTF3, TIAM1, MALL, AKAP6, STRN3, STK4, TRAF1, ZBTB17, CHAF1A, NR1H3, CALCOCO2, EIF2B5, TARDBP, FADD, MAP2K5, MAPK7, PAK2, CBX3, CBLB, PSMD2, MMRN1, GPS2, SELENBP1, SRSF9, SRSF5, SRSF6, MAD2L1, PTGDR, TRIM28, STX3, G3BP1, CLN3, NMI, PTK7, SKP2, GRB10, MTA1, PPIL2, PPP2R5C, PDE3B, PDCL, MAPK8IP2, UBE2V1, ORC1, ILK, IKZF1, SNTA1, SNTB2, XRCC4, UNC119, OS9, GOLGA4, ADAM9, MYO9B, NFATC2, GAB1, SMAD4, BIRC3, PICALM, MTM1, SQSTM1, MED21, TRPC3, PRPF4B, EIF4EBP1, EIF4EBP2, RIPK1, HDAC1, CAMK2D, DCTN2, PKD2, NAE1, DGKZ, SNX1, MTMR2, CUL2, CUL3, CUL4A, CUL4B, TP53BP2, PTCH1, RAB32, FHL1, ACVR2B, ALCAM, RUNX3, PMAIP1, EXOSC2, BMPR2, SNTB1, GTF2H2, C1D, RAPGEF1, CACNA1C, RUNX2, CBFB, NFYC, CDK13, CKAP5, CIRBP, CAMK1, HNRNPD, TOB2, NID2, DAG1, BOP1, SEPT6, EIF3A, ARHGEF7, SPIDR, GIT2, TFDP1, DCTN1, NPAT, E2F2, EIF2B1, EIF4A2, SELPLG, CTTN, TRIM25, FASTK, FLNC, GAS6, HES1, SLBP, RBM39, NEDD9, FAT1, MCM6, ITPR3, MXD4, NBR1, ITPR1, PUM1, ESPL1, MDC1, KANK1, MELK, SMC1A, GSE1, DIP2A, LTBP1, CASP8, KIF22, MEF2D, CHD4, ARID5B, DRAP1, KPNB1, NR1D2, CUL7, FRMPD4, NCAPH, KIAA0101, EMC2, WTAP, MORF4L2, SEPT2, SART3, NCAPD2, SUZ12, EXOSC7, TRAM2, JOSD1, ARL6IP1, KARS, RRS1, POLD3, KIF14, POSTN, EEA1, NCF4, PDIA6, PAFAH1B3, PCOLCE, PEA15, CDK10, PRKD1, PCM1, PPP2R5A, PTGES3, STK38, NECTIN1, NONO, PTPRK, RABEP1, RNPS1, RBBP5, ERBB4, RALBP1, ZMYND11, ANKRD1, TMED2, PCBP1, TCEB1, TCEB2, UBE3C, TOMM20, PUM3, DLGAP5, TLR1, SEC23A, SHB, NR0B2, STIL, FCN2, SPA17, TAF5, TAF11, MAPRE2, TEAD4, TEAD2, TAF1A, TGFBI, NCOA2, DIXDC1, TRADD, TSN, TRIP11, TRIP13, TRIP6, TWIST1, MAPRE1, TSC22D1, ELAVL1, KISS1, TAB1, SLC1A5, MPPED2, NCOA1, SMAD2, SMAD1, ITSN1, UBE2V2, STK11, STXBP2, CCDC85B, VAMP3, NEDD8, ADIPOQ, USF2, RAB11B, EZH2, ZFHX3, ZYX, ZNF124, HSPB2, SEPT7, ADRM1, CCDC6, IGFBP7, PDCD2, SLC15A2, PKN1, PKN2, TAF12, CRY1, MAPK14, CDC37, DPYSL2, FXN, OCLN, DBN1, PTGIS, NFIL3, HIF1A, IFI16, CDKN3, CLPP, UGP2, AOC3, ATP6V1F, TPD52L1, LONRF1, SWI5, PDS5A, ZNF423, KIZ, QRICH1, HFE, FAM161A, TKFC, TBRG1, TIMM50, LGALSL, ANO6, MRPL51, AMOT, C4orf46, PDCD4, CEP55, NCBP3, KLHL12, PLEKHO1, HSD17B12, CDCA8, SGOL2, CCDC93, PAN3, TMEM97, ODF2, ZNF326, TTMP, NOM1, PDZD11, CENPW, DNAJC21, SGOL1, FAM76B, DOCK11, TJAP1, GNAS, BRMS1L, LDLRAP1, PLEKHS1, FNBP1L, UBR4, ARHGAP21, AVPI1, PHF19, RBM26, WLS, CPSF3L, DCAF8, COL13A1, DEPDC1, ATPAF1, CROCC, CDC42BPA, PDE4DIP, ARHGEF16, SHE, LRRC16A, CD276, TNS2, KANK2, ICE2, CEP135, TBC1D9B, INTS3, ANKRD40, ATL3, TTC19, SFRP4, ZFAND6, OTUD7B, LAIR1, THOC7, SIGIRR, LAMTOR1, JADE1, PTCRA, NIPBL, CXorf57, JMJD6, FAAP20, PTRF, MAST2, FAM117B, TATDN1, MTFR2, NFRKB, KLC3, LRRC8B, RFWD3, KLHL35, PSRC1, BORA, SHQ1, SPSB3, BRAT1, ZC3H14, LARP1, RICTOR, AGTRAP, FIP1L1, MOXD1, C6orf89, OLFM4, PLXDC2, APOOL, ATF7IP, RAD9B, MPRIP, HACD2, RNF111, CCDC141, RBPMS2, TBC1D9, C11orf57, PHLPP2, BBS12, USP34, RAPH1, IKBIP, KCTD1, RPS27L, CBLL1, NOL8, SUPT6H, RUFY3, RHOU, DHX30, CYFIP1, MCM10, COPS6, EPM2AIP1, DHX32, RAB11FIP2, CXXC5, SETX, NOTCH2NL, ZFYVE16, TMC6, NUFIP2, RNF144B, MAVS, NPHP3, COMMD6, WAPL, SPRED1, RBBP6, NECAB2, TECPR1, HUWE1, NEK8, SDCCAG8, ZBTB33, TMEM150A, PEG10, SYVN1, TTC7B, PABPN1, MTDH, MAGI2, RTN4RL1, NOXA1, ALYREF, CD163, TAX1BP1, CAND1, HOOK3, LONP2, NLRC5, CHD1L, GPBP1, RPS19BP1, CARM1, COMMD2, ANKLE2, CEP57, CACUL1, KIF18B, KMT5C, HOMER1, GATAD2A, DCP2, TMPRSS6, ERC1, ZDHHC17, CRLF3, SIAH1, TRAPPC5, CREBRF, FOXP4, MAP4K3, NOSTRIN, CCDC103, CARKD, FAM114A1, LRRC8A, CHERP, TRIM42, BBS7, WWC1, CCAR1, SLF2, SCUBE3, SKA3, DNAJC10, TP53INP2, SIRT2, FAM20C, TMEM183A, SMC5, YAF2, AMOTL1, SUPV3L1, FANCM, ZNF440, C1orf174, TRIM22, C6orf165, HACE1, MICU2, ZBED8, KIAA0319L, ZNF101, KMT2E, SCYL3, XRN1, UNC5B, ABI1, NLGN4X, SPG20, CNTROB, AHI1, CCAR2, VPS52, NUP93, CRIPAK, CFAP52, ARHGAP24, APITD1, AGGF1, ASCC3, CLIP4, PPM1K, MPP5, FNBP4, ZCCHC7, NIN, MINK1, ZNF276, TAB3, NKAP, CISD2, RPP25L, TBC1D19, COMMD1, RNF182, EID2, NATD1, CD177, ZNF655, KIAA1958, JMY, BANP, EIF1AD, SREK1IP1, IQUB, FAM73A, ZBTB38, FAM184A, GOLM1, PCSK9, POC1A, SPC24, SLC38A9, INO80E, SERBP1, KCTD6, HJURP, C11orf65, SMG8, TNRC6A, CPEB3, ABCF1, BVES, PIK3C3, MCPH1, ARMC2, APPL2, VPS37A, ZMIZ2, ZNF397, TMEM185A, FLCN, NUP43, NUP37, NUP35, REPS2, GPRC5A, BBS1, SPTSSB, DNER, MYRIP, FBXO18, CASC5, NPB, SVIP, ATL2, CEP70, TPCN2, THOC2, INADL, CTCFL, KIF18A, RP9, C1orf216, KCNG3, GADD45GIP1, WDR48, RHEBL1, GABPB2, BBS10, TTC8, MPLKIP, SMARCC2, ZNF420, UHMK1, OSR1, DEPTOR, PUM2, ZCCHC10, TBC1D16, ZNF502, ZNF564, TBC1D15, POC1B, SPATA18, ENOX1, LRRC20, PIFO, PNPT1, SPPL3, SPPL2A, HM13, AGR3, BICD2, NEK9, MGARP, LRRC8C, RB1CC1, MICAL1, PXYLP1, RNF128, SH3RF2, UTP15, GEMIN5, FBF1, RAPGEF6, PARD3, IPO4, FNIP1, UBASH3B, DUSP19, SETD7, SCARB1, THAP3, FRS2, ZC3H15, RAB2B, PPP1R13L, HDAC7, CEMIP, PTPMT1, PDCD6IP, FBLIM1, BLNK, TRIM41, MITD1, ZFAND2B, CHTF18, TMEM170A, SKA2, TNFAIP8L1, UBLCP1, ZFPM2, APH1B, KCNE4, PHIP, RASSF5, PRPF31, EDARADD, PALLD, METTL21A, GEMIN6, ATRIP, PSPC1, GPR98, SYNE2, NANOS1, PPM1E, MYLIP, KAT6B, RSPH1, KCTD13, TTN, RFFL, RAPGEF4, SEC14L1, CPT1B, GBF1, RTF1, TOPBP1, ELMO1, BAP1, FAM168A, NR4A3, NDRG1, DOCK2, TBC1D5, EDEM1, NUP205, APPBP2, ANKS1A, NSMAF, PIGK, SORL1, ANP32B, ESR2, TFG, RYR2, GTF2H4, HDAC2, STAM, PROX1, CREBBP, KAT6A, SYMPK, N4BP2L2, TAF15, GOLGA1, NRCAM, KAT2B, RPGR, INPP5D, DDX17, BCL2L2, TANK, KIFAP3, APBB2, RAD50, ERCC4, UFD1L, HPS1, GATA6, FGF13, FGF14, SMARCC1, RAB8B, BAD, KHSRP, ARHGEF2, EMG1, GLMN, USP13, CUL5, ATP6V0A1, LPP, RBPMS, EXT2, KISS1R, PRKCDBP, POP5, MYDGF, LOH12CR1, MAL2, PIGT, FBXO32, L3MBTL2, TMEM203, UBE2E3, WBP2, FBXW5, NCLN, TEKT1, PMEPA1, ERGIC1, UTP4, TP53INP1, MARVELD3, EXOC4, JAKMIP2, TTC17, CLUAP1, ACD, PBXIP1, MCUR1, KIAA1143, EME1, RAD51AP1, EXOSC8, BORCS7, ARRDC3, CREB3L1, SKA1, APH1A, ARL8A, TRIM43, UPRT, MOAP1, MIEF2, SYTL4, RPUSD4, HAUS1, FAF2, PLEKHB2, OPTN, AP2M1, TUBGCP3, GPRASP2, REPS1, DNAJC19, MSI2, SPDL1, ELP4, YIPF6, HOOK2, SEH1L, FBXO17, C19orf60, SGF29, MVB12A, PTCD3, CYFIP2, NRBF2, EDC3, CDCA5, STAMBPL1, CPNE2, DTD2, S100A16, OTUB1, DPH3, BICD1, MRPL48, ZNF274, VMP1, AURKB, DCUN1D1, SMARCD1, CDCA7L, DDX27, BORCS6, C5orf30, ZC2HC1A, TONSL, GRAMD3, SH3YL1, MED30, NAF1, INTS4, RBM17, AJUBA, ABHD14B, SEC22A, NSL1, PAWR, RSRC1, ITCH, LOXL4, EAF1, CHAMP1, L3MBTL3, SLC41A2, ZFYVE19, RITA1, ZC3H10, PBK, DNAJC1, ZNF512B, FAM84B, EXOC2, EHMT2, MARK4, PRMT6, DHRS1, CEP19, UBE2E2, C9orf72, PRIMPOL, AK8, PRICKLE1, YTHDC1, KREMEN1, VSTM2L, SPATA13, ZMAT2, ANKRD27, IPO9, NECAB3, INPP4A, UHRF2, NEDD4L, QKI, NEK1, SMG1, KIF20B, DLC1, TEFM, RAB3IP, MTMR9, VPS35, PHF12, HHIP, MAGI1, SPAG5, ZNF300, SNX18, PASK, NR1H4, CIC, MED15, ERGIC2, MCCC1, USP28, FNBP1, TRIB3, TP53RK, RANBP9, CSRNP1, UBL7, SRPK1, SMC6, DCLRE1C, STRBP, ORAI2, ZNF587, CEP89, RSF1, RBM15, SPEN, UHRF1, TCF12, MYCBP, CDC5L, PFDN5, GPER1, MPHOSPH8, PKP4, PIK3R4, P2RX4, S100A13, SCAF11, TEAD3, KLF6, TTC1, CDCA3, PHB2, RAD9A, PKMYT1, CHP1, KIF2C, MAP3K5, FEZ1, LYST, DOK1, HSD17B10, SMAD5, BARD1, HNRNPAB, LITAF, CDC6, NPAS2, MDFI, TXN2, EPAS1, CIB1, CCT7, PRMT1, PKP2, SH3GL2, CITED1, CITED2, RARRES2, VRK1, GDF15, NIPSNAP1, NCAPG, PAIP2, NABP2, ZFYVE21, TCF25, SOST, VIMP, SLF1, DBNDD2, CORO1B, BUD13, ORAI3, UQCC2, GINS4, UTP23, CENPK, RHNO1, FAM64A, CCM2, INPP5K, NDFIP1, SYT11, WAC, PAGR1, TMEM43, TBCD, NDUFAF3, CENPO, DOHH, SPON2, POLR3C, HNRNPUL1, PDCD10, RPP25, HTATIP2, DDX23, APOO, FAM195A, RSRP1, C9orf16, C1orf50, SLC25A23, DUSP26, ADI1, RNF126, SNRNP25, DSCC1, MLST8, PHF20, DUSP23, NUP58, GGACT, GNL3, TIMM21, TIPIN, TMEM106C, NUP85, ELOVL1, KATNAL1, HIRIP3, IFT27, CCDC94, RBM4, CARD10, SSBP3, SORBS1, TRPM6, LGR4, BBS2, BBC3, C1QTNF1, NAA15, PINK1, CLEC7A, TMEM59, OSBPL1A, FANCD2, EMILIN2, BEX2, PACSIN1, HDAC8, CADM1, POLDIP3, CDHR2, NIFK, PARD6B, HELZ2, NUF2, ASPSCR1, UACA, RAB34, WDR11, TBL1XR1, PRKD2, FAM129A, FOXP3, UBXN6, CD244, SPRY4, TRIM9, TRIM6, TRIM2, XPO4, CEP44, STRADB, WDR12, TINAGL1, NDEL1, DERL2, MAP1LC3B, SENP6, ELOVL4, CCDC90B, NIF3L1, CTDSP1, EIF5A2, MFF, NAA50, UBA5, MKRN2, PAIP1, KATNBL1, COMMD4, TOLLIP, USP44, RACGAP1, ENKD1, CCDC113, WWP1, GBP3, GABARAPL1, DDX47, RAB1B, NAPB, DNTTIP1, CSRNP2, SDCBP2, METTL9, TRPV6, UPF3A, CDT1, EHD4, SEMA6A, HSD3B7, BLZF1, SLC38A1, PDCL3, TNKS2, RASSF4, DHX36, HIPK2, ADAMTS10, FOXP1, KCTD10, TXNIP, ACBD3, CENPH, DSN1, CHMP4B, FBXL15, MAP1LC3A, RHOJ, FAM83D, SMARCAD1, FBXO44, RGCC, ZNF335, ELOVL6, FAM96A, OBFC1, ARMC7, RPAP3, EGLN3, GAREM1, DOCK5, METTL17, SUDS3, AUNIP, PHAX, CSRP2BP, NOL11, DDX31, MOB1A, AKTIP, ECT2, PLEKHF2, ZWILCH, REEP1, MED20, ELP3, LIN28A, MEAF6, ADGRL3, PLEKHA5, SMURF2, UPF2, PLEKHA2, CACYBP, RRAGC, BEX1, TNS1, SPC25, TAF9B, LGR6, APOBEC3G, CENPJ, MCCC2, METTL14, CWC22, SYTL2, TNRC6C, ROBO2, AGO4, CHD8, TRIM39, POLD4, GOPC, MYO10, CD209, SLC40A1, HMG20A, SSU72, VTA1, TNFRSF12A, MYOZ1, PARD6A, ACKR4, EXOSC4, NOP10, NGB, BRD7, MKKS, PNRC2, MED4, CD93, MRPL40, CRTAC1, HEYL, TCF7L2, RTN4, CYLD, HPS4, RRAGD, PFDN4, KMT5A, NECTIN3, EXOSC3, KIF13B, GPHN, NPDC1, PDLIM7, POLE4, EIF2B3, MBNL1, DLL4, ARHGEF4, ARHGEF3, EIF4ENIF1, TSHZ2, SH2B1, POLE3, CHRAC1, PRTFDC1, BAZ1A, LATS2, AASDHPPT, PLSCR4, SMCO4, CDC42SE2, UBQLN4, SNX15, RAB6B, INIP, RASSF1, RPRM, TOMM22, RAD18, HOMER3, PDS5B, RNF146, ACSS1, TMEM106B, UFSP2, TDP1, POT1, NUDT15, EXOC1, NDFIP2, TMEM30A, PARVA, INTS7, FANCI, ARL8B, GNL3L, ASF1B, INTS10, DNAAF2, THAP1, MED9, RNF216, PAG1, PARPBP, PAK1IP1, AURKAIP1, CLN6, NMRK1, GEMIN8, NDUFB11, HYPK, LYAR, SYBU, MKS1, NDE1, CDKN2AIP, GAR1, STAB1, AATF, SPHK1, ABI2, DACT1, BCLAF1, ELOVL5, MIS18A, UGGT1, CDK12, PLK2, ERAP1, PRR13, CLIC5, DTL, ZNF224, MAT2B, EHD3, FLRT3, SEPN1, MPP6, CWC15, MRPL15, CRIPT, NDUFAF4, HACD3, NDUFA13, VAPA, AKAP7, SH3BP4, HMG20B, SPATA7, ZBTB4, STIM2, SLAIN2, FNIP2, BCCIP, ARMCX1, CTTNBP2NL, CHD7, CPSF2, RCOR3, KLHL42, ANKFY1, RERE, SUCLA2, WRAP73, DPM3, ATXN10, NFKBIL1, DNMT3B, SPRR3, ORC3, CLCF1, SAE1, NLK, PI4KB, MYOT, PPARGC1A, UXT, ASH2L, HDAC6, SPAST, VPS29, EIF3K, CTSZ, DNAJB9, RNF14, CTNNAL1, MORF4L1, NXF1, SEL1L, SLC25A10, TJP2, DNAJB4, VTI1B, LRWD1, ZRANB1, TES, KDM5B, DMBT1, PARP2, LIMD1, SEC63, ZC3H7B, KLHL3, SUN2, LAMTOR3, AFF4, MLH3, MKRN1, CHORDC1, TBK1, TRPS1, DCDC2, SLC7A8, DDX20, NUFIP1, USP25, SAP30BP, LGALS13, PUF60, EVL, EIF2B4, ATP6V1H, DACH1, DNAI1, ZNF639, MUTYH, BAZ1B, KLF15, DUSP13, AK3, SCOC, CNOT7, TSPYL4, GGT7, RABGEF1, ANXA10, ZMYM5, ERRFI1, TSKS, CDC23, GGA2, GGA1, NAGPA, ZNF580, LSM7, FEM1B, FBXO10, FBXO9, FBXL2, TNIK, PITPNC1, PILRB, PILRA, NXT1, NUDT5, GTF3C4, ADAMTS7, FBXO5, AMFR, AGO2, VAV3, MYH2, NUP50, ZHX1, INTS6, BAG5, RAB21, RAB22A, PNMA2, BLOC1S6, NRXN1, RAB23, CCPG1, ASAP1, MKL2, ANKRD50, YEATS2, CNOT6, MYO5B, FZD4, CORO1C, PYCARD, PADI4, FZR1, HPCAL4, MYO6, COL17A1, NFU1, PRPF19, SYNPO2, SUFU, BOK, SNX12, G3BP2, POLI, STUB1, MAGED2, CDC14A, SNX6, FAF1, PPIE, TIMELESS, TTF2, TFR2, MACF1, PPP6R1, TNRC6B, SMG5, EXOC7, USP22, TBC1D2B, TRAK1, DICER1, MAPRE3, PA2G4, EXO1, SMC3, MAPK8IP1, HDAC5, ZNF148, HHLA3, TRPC6, NIP7, RUVBL2, CDYL, AKT3, GINS2, LZTS1, HPSE, RNF6, POLH, PRELID1, RUVBL1, TNFSF13B, BCS1L, INVS, FARSA, ITM2B, ASF1A, DRG1, BTRC, CNPY2, SSX2IP, ATP11B, DLGAP4, STK38L, NISCH, PIKFYVE, EPB41L3, SIK3, USP20, FAN1, LAMTOR2, COA3, PTPN22, POLR1D, AP3M1, LEMD3, CARHSP1, THRAP3, GIT1, UBE2D4, SUGT1, LSM2, SH3GLB1, CAB39, LUC7L2, SBDS, CCDC53, FAM96B, PAM16, BOLA1, RABGAP1, TSC22D4, NOC2L, KNSTRN, L3MBTL1, ZNF175, TLN1, KIF3A, TRRAP, TCAF1, DAAM1, PLXND1, USP15, FAM65B, GPSM3, DTNA, LOXL2, MAP4K5, WIPI2, AMMECR1, ARIH1, LSM5, LSM4, SAMM50, CSDC2, HSPB11, CEP83, NUB1, YTHDF2, NME7, PCDHB14, HEY1, UCHL5, ATP6V1D, TNPO3, N6AMT1, GMPPB, MAFB, RBM8A, WIF1, SNX9, SNX5, HEBP2, FHOD1, NCOR2, F11R, SPIN1, FKBP7, TACC3, EID1, ARFGEF2, MAD1L1, STK24, COMMD10, SNCAIP, TEX264, IGF2BP2, SLC30A1, SESN1, TNFRSF11A, NCOA3, SLC4A4, MAP3K4, WASF2, LOC93622

GO:0005516

MF

calmodulin binding

Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.

MYO1G, MYO1C, CASK, ADCY3, EDF1, MYO1D, PCNT, EGFR, MAP2, GAP43, DDX5, ATP2B1, SYT1, ATP2B4, ITPKA, NOS3, MARCKS, MIP, CTH, USP6, MYH9, MYH11, RGS2, PHKA2, PHKA1, IQGAP1, MAPKAPK2, PCYT1A, RGS4, CNN1, DAPK1, GEM, RRAD, VAMP2, SPTBN1, EWSR1, CALD1, TJP1, PPP3CA, CAMSAP2, MYO1E, STRN3, SNTA1, SNTB2, MYO9B, CAMK2D, IQGAP2, SNTB1, CACNA1C, CAMK1, EEA1, RYR3, CNN3, MYLK, UBR4, CAMSAP1, PNCK, IQGAP3, CAMK1D, AEBP1, ASPM, TRPV1, ENKUR, TRPM4, TTN, RYR2, RIT1, MKNK1, IQCG, TRPV6, TRPV4, MKNK2, MYO10, PLCB1, STRN4, SPHK1, NDUFAF4, CAMSAP3, ARPP21, ADD3, FBXL2, MYH2, MYO5B, MYO6, INVS, MYO5A, MYH4

GO:0005518

MF

collagen binding

Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).

SMAD7, COCH, ITGA10, PDGFB, FN1, VTN, PDGFA, VWF, DCN, CTSL, CTSB, SPARC, SRGN, NID1, MMP9, CD44, ITGA2, PPIB, CTSS, COL5A3, ITGA3, CTSK, COMP, SERPINH1, LUM, SMAD3, COL14A1, DDR1, ADAM9, SMAD4, ITGA9, NID2, SPARCL1, PCOLCE, TGFBI, HSD17B12, CCBE1, PODN, GPR126, C1QTNF1, DSPP, ITGA11, PCOLCE2, ADGRG1

GO:0005519

MF

cytoskeletal regulatory protein binding

Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton.

CDC42EP3

GO:0005520

MF

insulin-like growth factor binding

Interacting selectively and non-covalently with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.

CYR61, WISP2, WISP1, IGF1R, IGFBP1, IGFBP3, CTGF, HTRA3, IGFBP7, HTRA1, KAZALD1, ESM1, CRIM1

GO:0005521

MF

lamin binding

Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.

BNIP3L, PRNP, PPP1CC, IFI27, TMPO, TMPO, PLCB1, SUN2

GO:0005522

MF

profilin binding

Interacting selectively and non-covalently with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.

RHOQ, HTT, CTTN, DBN1, EVL, PCLO

GO:0005523

MF

tropomyosin binding

Interacting selectively and non-covalently with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.

NEBL, S100A6, TNNT1, TMOD1, LMOD1, CALD1, PYCARD

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

UBA6, UBE2QL1, VWA8, SMCHD1, MYO1G, TK2, DDX39A, MYO1C, CDC7, PIK3CD, RTCA, PIK3C2A, PLK4, DDX3X, NME4, UBE2C, ACACB, PDXK, CHD1, CHD2, TOR1A, ABCD4, RIOK3, MAP2K7, CHEK1, OPLAH, CASK, AURKA, SLC27A2, BTAF1, PIP5K1B, MAST4, PFAS, DCLK1, MUSK, MAPK13, ABCC4, ABCC5, DHX15, IRAK2, DYNC1LI2, MAP3K13, DAPK3, MAP3K7, RIPK2, RAD51C, ATP8B1, ASNA1, BUB1, GATC, KIF1C, ORC5, DHX16, SMARCA5, ADCY3, KIF5C, NUAK1, PIP5K1C, KIF1B, ACSL4, ADCY9, BUB1B, JAK2, PFKFB2, DNAJA2, FAM20B, ATP9A, ROCK2, VPS4B, ENTPD3, ULK1, NME6, POLQ, ERN1, RPS6KA5, TRMU, RAD51D, GATB, PAK3, CLPX, SLC22A5, RECQL4, STK17B, MYO1D, ABCA8, RHOBTB3, FSBP, UBE4B, KIF20A, KIF4A, PAPSS2, SMC2, FARS2, ABCA1, MAP4K4, LATS1, TTLL1, EGFR, PGK1, AK1, ASS1, RAF1, TK1, ERBB2, NTRK1, TP53, ATP1B1, PCCA, PRKCB, INSR, FYN, CDK1, CSF1R, EPRS, HSP90AA1, LYN, IGF1R, HSP90AB1, ASNS, MET, PDGFRB, FGR, HSPA1A, HSPA1B, KIT, HSPD1, HSPA5, BCR, FGFR1, TOP2A, PC, MTHFD1, PSKH1, CDK4, PRPS2, HARS, CKB, CKMT1A, XRCC5, CFTR, GTF2F2, PKM, HSP90B1, IDE, DARS, NME1, PFKFB1, PDGFRA, ATP2A2, HSPA6, PRKCA, CKMT2, SYN1, PRKACA, CTPS1, DDX5, PFKL, PSMC3, TCP1, ERCC2, LIG1, HK1, ATP2B1, MSH3, NPR2, MAK, CDK11B, ATP6V1B2, FGFR2, ERBB3, GART, PAICS, UBA1, NME2, ENPP1, JAK1, ATP2B4, ITPKA, DTYMK, RRM1, CDK2, MCM3, TARS, ACVR2A, AK4, MAPK3, DCK, CAD, ABCD3, SMARCA1, MAPK1, EPHA3, EPHB2, LTK, ATP5D, CMPK1, PEBP1, WEE1, MAT2A, DNAJA1, AKT1, AKT2, GK, ACSL1, ABCC1, TTK, MCM4, MCM5, MCM7, HSPA1L, HSPA4, GRK5, RFC4, RFC2, MYH9, TIE1, ADRBK2, MYH11, CHKA, FLT4, PSMC2, MAP2K2, BMPR1A, ACVR1B, TGFBR1, TGFBR2, CCT6A, MLH1, RFC5, UBA7, CSK, MAP3K8, PRKCI, ACTR1B, SKIV2L2, PIK3CA, PIK3CB, ABL2, HELZ, MSH2, GRK6, SYK, PSMC4, MAPK8, MAPK9, MKI67, RECQL, ATRX, NSF, GCLC, CSNK1A1, CSNK1D, PIK3CG, MAPKAPK2, CDK8, CCT3, CDC34, UBE2A, HARS2, SARS, CSNK1E, MCM2, CLK2, GSK3B, SEPHS1, MTHFS, GMPS, CDK7, CCT8, ATP1A2, PAPOLA, DNA2, SMARCA2, SMARCA4, IRAK1, CLCN3, CLCN4, CLCN5, CLCN6, CLCN7, PRKX, ADCY7, NEK2, NEK3, NEK4, UBE2E1, JAK3, MAP2K6, MSH6, KIF11, PLK1, DAPK1, MVD, LIMK2, BLM, RARS, PMS1, YARS, PRKAG1, PRKAA2, ATP12A, EPHA5, EPHB4, EPHB1, EPHA4, ALDH18A1, VCP, SIK1, NLRP5, ACTB, EIF4A1, PRPS1, UBE2D3, UBE2M, ACTR3, ACTR2, ABCE1, HSPE1, PSMC1, UBE2H, PSMC6, ACTA2, UBE2B, ACTG1, ACTG2, UBE2I, ACTC1, PIP4K2B, SRPK2, CCT2, PRKDC, ATP2C1, CDK3, CDK6, CDK5, CDK16, HNRNPU, RUNX1, GALK2, ROR1, CENPE, KIF23, MAP2K1, TEK, FKBP4, GUCY2D, MVK, PRKCQ, ACVR1, PTK2, PRKCD, RNASEL, TYRO3, RAD51, TNK2, DDR1, SLFN5, DMPK, DNAH14, HSPA14, TWF1, MERTK, ILF2, MYO1E, STK4, COASY, MAP2K5, MAPK7, PAK2, G3BP1, PTK7, ORC1, ILK, MYO9B, PRPF4B, RIPK1, CAMK2D, ITPK1, DGKZ, ACVR2B, RUNX3, BMPR2, RUNX2, CDK13, CAMK1, DYNC1H1, EIF4A2, FASTK, MCM6, KCNJ11, MELK, SMC1A, KIF22, CHD4, SHPRH, LARS2, KARS, KIF14, PDK1, CDK10, PRKD1, STK38, PPP2R4, ERBB4, RPS6KA2, RPS6KA1, TESK1, TRIP13, MYLK, STK11, PKN1, PKN2, MAPK14, NTRK2, PDK4, AMHR2, UBE2S, GUK1, DGUOK, PFKFB3, PFKFB4, AAK1, ERCC6L, HKDC1, PGS1, CHD9, TKFC, TTLL9, NADK2, AASDH, ATP13A5, SBK1, ACSM3, PAN3, CMPK2, DDX60L, EARS2, TOR2A, DGKK, ABCC10, IDNK, ERCC6L2, ATAD3B, MLK4, CDC42BPA, NADSYN1, TWF2, STYK1, MAST2, PNCK, PPIP5K1, PAPD4, ATAD2, MTHFD1L, DSTYK, AATK, DNAH12, GK5, BBS12, NEK10, DDX46, DHX30, PARS2, DHX32, NRK, SETX, DHX29, NEK8, STK32C, AACS, LONP2, NLRC5, CHD1L, DGKH, KIF18B, SGK223, CAMK1D, DNAH10, MAP4K3, NAV2, CARKD, TEX14, DHX40, FAM20C, SMC5, DHX37, SUPV3L1, FANCM, SCYL3, ABCA6, TOR2A, UBE2J2, ASCC3, MINK1, ATAD1, TDRD9, STKLD1, ABCF1, PIK3C3, TRPV1, ANKK1, FBXO18, NEK11, TTL, KIF18A, BBS10, UHMK1, NUBPL, NEK9, TRPM4, DDX54, HELQ, STK35, NEK7, DNAH5, ATP8B4, GSG2, CHTF18, DCAKD, DNAJA4, ABCA5, TTN, HSPH1, KIAA0232, DYRK2, RAD54L, SYN2, DDX17, RAD50, RFK, UBE2E3, UBE2W, SGK3, ULK4, DNAH11, KTI12, MMAB, AURKB, DDX27, MASTL, MYO19, PBK, SCYL1, MARK4, UBE2E2, AK8, NEK1, TRNT1, SMG1, KIF20B, ALPK1, TRPM7, MAGI1, PASK, MCCC1, PEO1, TRIB3, TP53RK, SRPK1, SMC6, NMNAT3, YME1L1, PIK3R4, P2RX4, PKMYT1, KIF2C, MAP3K5, CDC6, CCT7, TEP1, VRK1, MKNK1, DDX23, FICD, KIFC1, KATNAL1, PAPOLG, CDK19, TRPM6, PINK1, HELZ2, WNK3, PANK2, PRKD2, UCK2, STRADB, DDX24, UBA5, SIK2, QRSL1, DDX47, ABCG8, EHD4, TAOK3, DHX36, HIPK2, TPK1, TOR3A, WNK1, SMARCAD1, DHX35, PIF1, ACSS3, YTHDC2, ATP13A3, UBE2Z, DDX31, CNNM2, PANK3, UCK1, CLK4, TRPV4, MKNK2, ETNK1, NEK6, MCCC2, CHD8, CSNK1G1, MYO10, ABCB6, PNPLA8, UBE2T, MKKS, ATP13A2, KIF13B, GPHN, ACSS2, CTPS2, ABCB10, LATS2, HELLS, KIF15, NRBP2, BMP2K, PDS5B, SMC4, MDN1, ACSS1, DDX28, ATAD3A, MTPAP, NMRK1, UCKL1, DDX43, SPHK1, DNAH9, ZAK, CDK12, PLK2, EHD3, NDUFA13, MARK1, PAK7, CHD7, DNAH1, EIF2AK4, STARD9, SUCLA2, NLK, PI4KB, SPAST, EPHA6, ABCF2, PRKAG3, MLH3, CHORDC1, TBK1, IP6K2, DDX20, SHPK, BAZ1B, AK3, MCM8, TNIK, TLK1, ACSL6, MYH2, TAOK2, RIMKLB, MYO5B, TPX2, MYO6, TTF2, DICER1, CDK11A, SMC3, GNE, RUVBL2, AKT3, CHKB, RUVBL1, BCS1L, FARSA, ITM2B, ATP11B, STK38L, PIKFYVE, SIK3, DDX52, THRAP3, UBE2D4, RTCB, KIF3A, MYO5A, MAP4K5, HYOU1, NME7, CDC42BPB, IRAK3, RAD54B, MYH4, STK24, CSNK1G3, MAP3K4, DDX49

GO:0005525

MF

GTP binding

Interacting selectively and non-covalently with GTP, guanosine triphosphate.

GTPBP10, RAB27B, RHOD, RAB29, OPA1, EIF5B, RP2, MFN2, DIRAS3, NRAS, KRAS, TUBB4A, GNAI2, SCG5, INSR, TUBB, HSP90AA1, ANXA6, HSP90AB1, GNAI3, RAP2A, RRAS, RALA, RALB, EEF2, RAC2, GSPT1, NME1, RHOQ, ARF4, RAB3B, RAB5A, NPR2, TGM2, TUBG1, AK4, GNA11, ADSS, GBP1, GBP2, PCK1, TRIM23, GNL1, EIF2S3, GLUD2, ARL4D, SEPHS1, GNAQ, RAB5C, RAB7A, RAB9A, RAB28, RAB27A, DAPK1, SUCLG1, EIF5, GEM, RRAD, RAC3, CDC42, SRP54, RAB4B, RAB2A, RAB5B, RAP2B, RHOA, RRAS2, RAB11A, RHOB, RAB1A, RAP1A, RAC1, GNAI1, EEF1A1, TUBA1B, TUBA4A, TUBB4B, ARF1, ARF5, GNAS, FKBP4, GUCY2D, GNA12, EEF1A2, ARL16, ARHGEF5, RAB40B, ARHGAP5, TUBB3, RAB31, RAB32, TUBA3C, TUBB2A, RAB33A, SEPT6, SEPT2, RHEB, RAB11B, SEPT7, PCK2, TSR1, RABL6, IFI44L, GNAS, ATL3, RAB12, GBP6, TUBA1A, RHOU, MMAA, ARL17A, RASEF, ADSSL1, GTPBP8, GUF1, NIN, ARL14, ATL2, RHEBL1, URGCP, RAB2B, RAB8B, RIT1, GTPBP3, RERG, ARL8A, UPRT, RASD2, RAB39B, NUDT16, ARL5B, GFM1, RASL10B, RASL11B, MTG1, TUBB6, TUBB2B, GNL3, IFT27, RAB34, GBP3, RAB1B, EHD4, TUBB1, RHOJ, MTG2, RRAGC, RRAGD, RAB6B, ARL8B, GNL3L, NKIRAS1, EHD3, DNAJC27, AK3, TUBE1, TUBD1, RAB21, RAB22A, RAB23, TPX2, AGAP1, RASD1, DRG1, HBS1L, MFHAS1, SRPRB, GMPPB, ARL5A, SAR1B

GO:0005528

MF

FK506 binding

Interacting selectively and non-covalently with the 23-membered macrolide lactone FK506.

NFATC1, FKBP2, FKBP3, FKBP4, FKBP5, FKBP10, FKBP14, FKBP11, FKBP7

GO:0005534

MF

galactose binding

Interacting selectively and non-covalently with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.

COLEC12

GO:0005536

MF

glucose binding

Interacting selectively and non-covalently with the D- or L-enantiomer of glucose.

SLC2A3, G6PD, GYS1, HK1, UGP2, HKDC1

GO:0005537

MF

mannose binding

Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.

CLN5, MBL2, IGF2R, MRC1, BSG, LMAN2L, CD209

GO:0005539

MF

glycosaminoglycan binding

Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.

SERPINA5, SERPINE2, DCN, VCAN, BGN, TGFBR2, TGFBR3, NDNF, SPOCK2, EPYC, SPOCK3

GO:0005540

MF

hyaluronic acid binding

Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.

NCAN, HMMR, HAPLN1, VCAN, CD44, TNFAIP6, C1QBP, HYAL2, CEMIP, STAB2, BCAN, STAB1, LYVE1

GO:0005542

MF

folic acid binding

Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.

DHFR, TYMS, FOLR1, SLC19A1, MTHFS, SLC46A1

GO:0005543

MF

phospholipid binding

Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.

NR5A2, SEC14L2, ABCA1, GOT2, APOA1, APOE, APOA2, APOC3, APOH, ANXA1, APOB, ANXA5, PLA2G2A, PTAFR, PON1, GRK5, NUP62, SNCA, PRKCI, VAMP2, SPTBN1, PLA2G7, APOA5, NBEAL1, NUP35, NSMAF, BAD, SYTL4, OSBPL1A, PACSIN1, NUP62CL, SPTBN4, MAP1LC3A, BIN2, ARHGAP26, NSFL1C, PLA2G4C, AGAP1

GO:0005544

MF

calcium-dependent phospholipid binding

Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.

ESYT2, ANXA1, ANXA2, ANXA6, ANXA5, ANXA4, ANXA3, SYT1, PLA2G4A, ANXA11, C2CD5, SYTL5, SYTL4, SYTL2, ANXA10, PCLO

GO:0005545

MF

1-phosphatidylinositol binding

Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.

SYT1, PICALM, EEA1, ZFYVE16, SCARB1, PLEKHA4, PLEKHA5, ZFYVE1, SNX9

GO:0005546

MF

phosphatidylinositol-4,5-bisphosphate binding

Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.

MYO1G, KRIT1, TULP3, ANXA2, PFN1, ALOX15, SYT1, ACTN2, TIRAP, FCHO2, TWF1, FRMPD4, LDLRAP1, TWF2, COMMD1, STXBP6, PARD3, SNX21, SNX18, MAPKAP1, SYTL2, ADAP2, PLCB1, EXOC1, MARK1, ASAP1

GO:0005547

MF

phosphatidylinositol-3,4,5-trisphosphate binding

Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.

MYO1G, OGT, CYTH3, ADAP1, NPM1, AKT1, IQGAP1, IQGAP2, ZFYVE16, COMMD1, PARD3, ARAP3, ARAP2, GBF1, ARAP1, MAPKAP1, RACGAP1, ZFYVE1, MYO10, ADAP2, ASAP1

GO:0005548

MF

phospholipid transporter activity

Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.

ABCA1, APOA1, MFSD2A, OSBPL8

GO:0005549

MF

odorant binding

Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell.

OR5A2, OR5L2, OR14C36

GO:0008009

MF

chemokine activity

The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.

CXCL14, PPBP, PF4, CXCL1, CXCL8, CCL3, CCL4, CCL2, CCL5, CXCL2, CXCL5, CXCL12, CCL20, CCL8, CXCL6, CXCL16, CKLF

GO:0008013

MF

beta-catenin binding

Interacting selectively and non-covalently with the beta subunit of the catenin complex.

TAX1BP3, SMAD7, AXIN1, KLF4, FOXO3, PARK2, TBL1X, ESR1, GLI3, AR, CDH2, APC, CDH5, CTNNA1, RORA, NR4A2, SOX9, NUMB, PSEN1, GSK3B, SKP1, CXADR, SMAD3, FOXO4, EP300, FOXO1, PTPRJ, SHROOM2, KANK1, PTPRK, CARM1, DLG5, LZIC, MED12, DACT3, TBL1XR1, SOX17, CHD8, TCF7L1, TCF7L2, DACT1, ASH2L, HDAC6, SUFU, BTRC

GO:0008017

MF

microtubule binding

Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.

EML1, KRIT1, DYNC1I1, MID1, BIRC5, BCL2L11, PRC1, ZNF207, KIF1C, KIF5C, OPA1, KIF1B, PEX14, TPPP, KIF20A, KIF4A, VAPB, EML2, CRYAB, PRNP, GAPDH, S100A8, S100A9, MAPT, MAP2, NEFH, TPT1, EZR, APC, CLIP1, SNCA, LRPPRC, MAP1B, KIF11, PLK1, GABARAPL2, RAB11A, RAE1, MAP1A, CENPE, KIF23, FMR1, GOLGA2, TIAM1, KIF22, CHD4, FAM175B, KIF14, CNN3, MAPRE2, DPYSL2, CCDC88A, CAMSAP1, SAXO2, MAST2, KLC3, PSRC1, HOOK3, GAS2L3, CEP57, KIF18B, KIF18A, MDM1, SKA2, NDRG1, FGF13, ARHGEF2, JAKMIP2, SKA1, MARK4, KIF20B, CHP1, KATNB1, KIFC1, KATNAL1, NUSAP1, NDEL1, MAP1LC3B, RACGAP1, MAP1LC3A, FAM83D, REEP1, TRPV4, EML4, KIF13B, KIF15, SYBU, NDE1, CRIPT, VAPA, STARD9, UXT, HDAC6, SPAST, SUN2, MACF1, MAPRE3, LZTS1, SBDS, HDGFRP3, KIF3A

GO:0008020

MF

G-protein coupled photoreceptor activity

Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.

OPN1SW, ELOVL4, OPN3

GO:0008022

MF

protein C-terminus binding

Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.

MIF4GD, MYO1C, FOXN3, KPNA3, SDCBP, PEX12, KCNK3, TAX1BP3, DAPK3, JAK2, TBL1X, VPS4B, YEATS4, EML2, BCL10, ERBB2, ATP1B1, ERCC1, VIM, TOP2A, XRCC5, TCF4, ATP2A2, ERCC2, SDC1, ATF4, NCF2, SYT1, FBLN1, CTGF, CORO1A, YWHAB, STIP1, CTNNB1, PHB, PPP1CC, COIL, ID1, OPRL1, CSK, MSH2, MKI67, YAP1, CENPF, MRE11A, CDK7, BCAM, BRCA2, ATXN1, SYNJ2BP, PPP2CB, DLG4, DAB2, HSPG2, MAP2K1, DST, ZBTB16, RAD51, TJP1, EP300, SREBF2, CDC20, DLG1, ITGB3BP, XRCC4, NPAT, KCNJ11, MDC1, MAPRE1, CEP135, NIPBL, PXK, SIAH1, CEP120, TOPBP1, ERCC4, MED12, OPTN, HIC2, MAGI1, PHB2, CIB1, CITED1, SDCBP2, GOPC, VTA1, MID1IP1, IFT46, HOMER3, RBFOX1, SAE1, PLEKHB1, AGO2, HPCAL4, PRRC2C

GO:0008026

MF

ATP-dependent helicase activity

Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.

BLM, ERCC6L2, TTF2

GO:0008028

MF

monocarboxylic acid transmembrane transporter activity

Enables the transfer of monocarboxylic acids from one side of the membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.

SLC16A6, SLC16A3, SLC16A7, BSG, SLC16A14, SLC16A9

GO:0008035

MF

high-density lipoprotein particle binding

Interacting selectively and non-covalently with high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE.

APOA1, APOA2, CD36, SCARB1, APOL2

GO:0008046

MF

axon guidance receptor activity

Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.

EPHB2, EPHB1, ROBO2

GO:0008047

MF

enzyme activator activity

Binds to and increases the activity of an enzyme.

OGT, CFLAR, ASAP2, PPP1R12B, PRKRA, PSAP, CXCL1, TRIM23, MMP15, MMP16, CASP9, PRKCD, TAB1, HSPB2, PITRM1, APOA5, RICTOR, MGST2, RAB3GAP2, SAE1, DBF4, GTF3C4, MMP24

GO:0008048

MF

calcium sensitive guanylate cyclase activator activity

Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.

GUCA1C, GUCA1B

GO:0008061

MF

chitin binding

Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.

CHI3L1, CTBS, CHIT1

GO:0008066

MF

glutamate receptor activity

Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.

GRM8, GRM6, GRM3

GO:0008073

MF

ornithine decarboxylase inhibitor activity

The stopping, prevention or reduction of the activity of the enzyme ornithine decarboxylase.

OAZ2, OAZ1

GO:0008080

MF

N-acetyltransferase activity

Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.

ESCO2, NAT14, NAT9

GO:0008081

MF

phosphoric diester hydrolase activity

Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

PLCXD2, PLCXD3

GO:0008083

MF

growth factor activity

The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.

MSTN, EREG, GDF9, FGF18, DKK1, CSPG5, GDF11, BMP10, FGF19, BMP15, F2, AGT, TIMP1, PDGFB, TGFA, TGFB1, NGF, GH1, IGF2, PPBP, AMH, PDGFA, IGF1, INHA, IL6, GPI, INHBA, FGF2, CXCL1, INHBB, BMP2, BMP4, BMP3, TDGF1, BMP1, HGF, LIF, AREG, VEGFA, TYMP, OGN, IL11, KITLG, MDK, FGF7, BMP6, IL10, BDNF, GRN, CTGF, IL12A, FGF9, BMP8B, BTC, THBS4, LEP, GDF5, CXCL12, PGF, VEGFB, VEGFC, HDGF, INHBC, GFER, FGF12, TGFB2, JAG1, NDP, NRG1, EFEMP1, RABEP1, IL34, BMP8A, FGF13, FGF11, FGF14, HBEGF, GDF15, PDGFD, CD320, PDGFC, CLCF1, OSGIN1, NENF, HDGFRP3

GO:0008092

MF

cytoskeletal protein binding

Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).

FRMD3, TOR1A, LDB3, NEBL, FARP2, ALDOA, FABP3, ANXA2, TPM1, ALDOC, B4GALT1, DES, PTPN4, CORO1A, ACTN2, CDK5, ANK3, DLG1, PKD2, FLNC, ABI1, DLG5, MYLIP, SORBS1, PACSIN1, EPB41L4B, CAPN10, EPB41L4A, LIN7C, RPH3AL, FARP1

GO:0008093

MF

cytoskeletal adaptor activity

The binding activity of a molecule that brings together a cytoskeletal protein and one or more other molecules, permitting them to function in a coordinated way.

SDCBP, OBSL1, SORBS2, ANK2, ANK3, BICD1, ABI2, BAIAP2L1