go_id,ontology,go_term,term_definition,evidence
GO:0002540,BP,"leukotriene production involved in inflammatory response","The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.",IEA
GO:0004051,MF,"arachidonate 5-lipoxygenase activity","Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.",IDA
GO:0005506,MF,"iron ion binding","Interacting selectively and non-covalently with iron (Fe) ions.",IEA
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS
GO:0005635,CC,"nuclear envelope","The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).",IBA
GO:0005641,CC,"nuclear envelope lumen","The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.",IEA
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0006691,BP,"leukotriene metabolic process","The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.",IEA
GO:0016363,CC,"nuclear matrix","The dense fibrillar network lying on the inner side of the nuclear membrane.",IEA
GO:0019370,BP,"leukotriene biosynthetic process","The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.",IDA
GO:0019372,BP,"lipoxygenase pathway","The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.",TAS
GO:0031965,CC,"nuclear membrane","Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.",IEA
GO:0055114,BP,"oxidation-reduction process","A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.",IEA
GO:2001300,BP,"lipoxin metabolic process","The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.",TAS