go_id,ontology,go_term,term_definition,evidence GO:0000166,MF,"nucleotide binding","Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.",IEA GO:0000398,BP,"mRNA splicing, via spliceosome","The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.",IGI GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA GO:0003713,MF,"transcription coactivator activity","Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.",IEA GO:0003723,MF,"RNA binding","Interacting selectively and non-covalently with an RNA molecule or a portion thereof.",IEA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA GO:0005844,CC,polysome,"A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.",TAS GO:0008270,MF,"zinc ion binding","Interacting selectively and non-covalently with zinc (Zn) ions.",IEA GO:0030331,MF,"estrogen receptor binding","Interacting selectively and non-covalently with an estrogen receptor.",IDA GO:0031489,MF,"myosin V binding","Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.",IPI GO:0035255,MF,"ionotropic glutamate receptor binding","Interacting selectively and non-covalently with an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels.",IEA GO:0043204,CC,perikaryon,"The portion of the cell soma (cell body) that excludes the nucleus.",IEA GO:0044327,CC,"dendritic spine head","Distal part of the dendritic spine, that carries the post-synaptic density.",IEA GO:0044822,MF,"poly(A) RNA binding","Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.",IDA GO:0046965,MF,"retinoid X receptor binding","Interacting selectively and non-covalently with a retinoid X receptor.",IPI GO:0046966,MF,"thyroid hormone receptor binding","Interacting selectively and non-covalently with a thyroid hormone receptor.",IBA GO:0048471,CC,"perinuclear region of cytoplasm","Cytoplasm situated near, or occurring around, the nucleus.",IDA GO:0071277,BP,"cellular response to calcium ion","Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.",IMP GO:1903506,BP,"regulation of nucleic acid-templated transcription","Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.",IEA