go_id,ontology,go_term,term_definition,evidence
GO:0005201,MF,"extracellular matrix structural constituent","The action of a molecule that contributes to the structural integrity of the extracellular matrix.",IBA
GO:0005509,MF,"calcium ion binding","Interacting selectively and non-covalently with calcium ions (Ca2+).",IDA
GO:0005576,CC,"extracellular region","The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.",IEA
GO:0005578,CC,"proteinaceous extracellular matrix","A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.",IEA
GO:0010811,BP,"positive regulation of cell-substrate adhesion","Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.",IEA
GO:0031012,CC,"extracellular matrix","A structure lying external to one or more cells, which provides structural support for cells or tissues.",IDA|ISS
GO:0050840,MF,"extracellular matrix binding","Interacting selectively and non-covalently with a component of the extracellular matrix.",IEA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA
GO:1903561,CC,"extracellular vesicle","Any vesicle that is part of the extracellular region.",IDA