go_id,ontology,go_term,term_definition,evidence GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0005884,CC,"actin filament","A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.",IBA GO:0006897,BP,endocytosis,"A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.",IEA GO:0007275,BP,"multicellular organism development","The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).",IEA GO:0007283,BP,spermatogenesis,"The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.",IEA GO:0008360,BP,"regulation of cell shape","Any process that modulates the surface configuration of a cell.",IBA GO:0017124,MF,"SH3 domain binding","Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.",IEA GO:0030048,BP,"actin filament-based movement","Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.",IBA GO:0030154,BP,"cell differentiation","The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.",IEA GO:0038096,BP,"Fc-gamma receptor signaling pathway involved in phagocytosis","An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.",TAS GO:0051015,MF,"actin filament binding","Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.",IBA GO:0051127,BP,"positive regulation of actin nucleation","Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.",IBA