go_id,ontology,go_term,term_definition,evidence GO:0000302,BP,"response to reactive oxygen species","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.",TAS GO:0004601,MF,"peroxidase activity","Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.",TAS GO:0004602,MF,"glutathione peroxidase activity","Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.",IBA GO:0005788,CC,"endoplasmic reticulum lumen","The volume enclosed by the membranes of the endoplasmic reticulum.",IDA GO:0016021,CC,"integral component of membrane","The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IEA GO:0055114,BP,"oxidation-reduction process","A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.",IEA GO:0098869,BP,"cellular oxidant detoxification","Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.",IEA