go_id,ontology,go_term,term_definition,evidence
GO:0000977,MF,"RNA polymerase II regulatory region sequence-specific DNA binding","Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.",IDA
GO:0000981,MF,"RNA polymerase II transcription factor activity, sequence-specific DNA binding","Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.",IDA
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA
GO:0006357,BP,"regulation of transcription from RNA polymerase II promoter","Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.",TAS
GO:0007517,BP,"muscle organ development","The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.",ISS
GO:0030154,BP,"cell differentiation","The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.",IEA
GO:0030308,BP,"negative regulation of cell growth","Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.",ISS
GO:0045892,BP,"negative regulation of transcription, DNA-templated","Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.",ISS
GO:0045893,BP,"positive regulation of transcription, DNA-templated","Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.",IDA