go_id,ontology,go_term,term_definition,evidence GO:0000015,CC,"phosphopyruvate hydratase complex","A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.",IEA GO:0000287,MF,"magnesium ion binding","Interacting selectively and non-covalently with magnesium (Mg) ions.",IDA GO:0004634,MF,"phosphopyruvate hydratase activity","Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.",TAS GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA GO:0006094,BP,gluconeogenesis,"The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.",IBA|IEA|TAS GO:0007568,BP,aging,"A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).",IEA GO:0042493,BP,"response to drug","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.",IEA GO:0042803,MF,"protein homodimerization activity","Interacting selectively and non-covalently with an identical protein to form a homodimer.",IEA GO:0043403,BP,"skeletal muscle tissue regeneration","The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.",IEA GO:0046982,MF,"protein heterodimerization activity","Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.",IPI GO:0061621,BP,"canonical glycolysis","The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.",TAS GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA