go_id,ontology,go_term,term_definition,evidence
GO:0004930,MF,"G-protein coupled receptor activity","Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.",IMP
GO:0006629,BP,"lipid metabolic process","The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.",NAS
GO:0007186,BP,"G-protein coupled receptor signaling pathway","A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription.  The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).",TAS
GO:0007568,BP,aging,"A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).",IEA
GO:0016021,CC,"integral component of membrane","The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IEA
GO:0040016,BP,"embryonic cleavage","The first few specialized divisions of an activated animal egg.",IEA
GO:1901991,BP,"negative regulation of mitotic cell cycle phase transition","Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.",ISS