go_id,ontology,go_term,term_definition,evidence GO:0000122,BP,"negative regulation of transcription from RNA polymerase II promoter","Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.",IDA|ISS GO:0000978,MF,"RNA polymerase II core promoter proximal region sequence-specific DNA binding","Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.",IDA GO:0000982,MF,"transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding","Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.",ISS GO:0001078,MF,"transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding","Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.",IDA GO:0003682,MF,"chromatin binding","Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.",IDA GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA GO:0031065,BP,"positive regulation of histone deacetylation","Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones.",IEA GO:0045599,BP,"negative regulation of fat cell differentiation","Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.",ISS GO:0046982,MF,"protein heterodimerization activity","Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.",IPI