go_id,ontology,go_term,term_definition,evidence GO:0005739,CC,mitochondrion,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",IEA GO:0005743,CC,"mitochondrial inner membrane","The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.",IEA GO:0005758,CC,"mitochondrial intermembrane space","The region between the inner and outer lipid bilayers of the mitochondrial envelope.",IDA GO:0005759,CC,"mitochondrial matrix","The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.",TAS GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA GO:0006631,BP,"fatty acid metabolic process","The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.",IEA GO:0016290,MF,"palmitoyl-CoA hydrolase activity","Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.",IDA GO:0032587,CC,"ruffle membrane","The portion of the plasma membrane surrounding a ruffle.",IEA GO:0035338,BP,"long-chain fatty-acyl-CoA biosynthetic process","The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.",TAS GO:0043491,BP,"protein kinase B signaling","A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.",IMP GO:0047617,MF,"acyl-CoA hydrolase activity","Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.",TAS GO:1902108,BP,"regulation of mitochondrial membrane permeability involved in apoptotic process","Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.",IMP