go_id,ontology,go_term,term_definition,evidence GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0005739,CC,mitochondrion,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",IEA GO:0005759,CC,"mitochondrial matrix","The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.",TAS GO:0042273,BP,"ribosomal large subunit biogenesis","A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.",IMP GO:0043023,MF,"ribosomal large subunit binding","Interacting selectively and non-covalently with any part of the larger ribosomal subunit.",IDA GO:0070130,BP,"negative regulation of mitochondrial translation","Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.",IDA GO:0090071,BP,"negative regulation of ribosome biogenesis","Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.",IEA