go_id,ontology,go_term,term_definition,evidence GO:0000070,BP,"mitotic sister chromatid segregation","The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.",TAS GO:0000776,CC,kinetochore,"A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.",IDA GO:0000777,CC,"condensed chromosome kinetochore","A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.",IEA GO:0000922,CC,"spindle pole","Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.",IDA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0007051,BP,"spindle organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.",IMP GO:0007059,BP,"chromosome segregation","The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.",IMP GO:0015630,CC,"microtubule cytoskeleton","The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.",IDA GO:0035371,CC,"microtubule plus-end","The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.",IDA GO:0051301,BP,"cell division","The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.",IEA GO:0051988,BP,"regulation of attachment of spindle microtubules to kinetochore","Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.",IMP|NAS GO:0072686,CC,"mitotic spindle","A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.",IEA