go_id,ontology,go_term,term_definition,evidence
GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA
GO:0003779,MF,"actin binding","Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.",IEA
GO:0004721,MF,"phosphoprotein phosphatase activity","Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.",TAS
GO:0004725,MF,"protein tyrosine phosphatase activity","Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.",IBA
GO:0005615,CC,"extracellular space","That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.",TAS
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005856,CC,cytoskeleton,"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.",IBA
GO:0006470,BP,"protein dephosphorylation","The process of removing one or more phosphoric residues from a protein.",IEA
GO:0008064,BP,"regulation of actin polymerization or depolymerization","Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.",TAS
GO:0008138,MF,"protein tyrosine/serine/threonine phosphatase activity","Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.",IEA
GO:0010591,BP,"regulation of lamellipodium assembly","Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.",IBA
GO:0030036,BP,"actin cytoskeleton organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.",NAS
GO:0035335,BP,"peptidyl-tyrosine dephosphorylation","The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.",IEA
GO:0050770,BP,"regulation of axonogenesis","Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.",ISS