go_id,ontology,go_term,term_definition,evidence
GO:0003677,MF,"DNA binding","Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).",IEA
GO:0003700,MF,"transcription factor activity, sequence-specific DNA binding","Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.",IMP
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA
GO:0005667,CC,"transcription factor complex","A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.",IEA
GO:0006325,BP,"chromatin organization","Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.",TAS
GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA
GO:0006355,BP,"regulation of transcription, DNA-templated","Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.",IBA
GO:0006357,BP,"regulation of transcription from RNA polymerase II promoter","Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.",TAS
GO:0008013,MF,"beta-catenin binding","Interacting selectively and non-covalently with the beta subunit of the catenin complex.",IEA
GO:0030111,BP,"regulation of Wnt signaling pathway","Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.",IEA
GO:0043565,MF,"sequence-specific DNA binding","Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.",ISS
GO:0044212,MF,"transcription regulatory region DNA binding","Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.",IDA
GO:0060070,BP,"canonical Wnt signaling pathway","The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.",IC
GO:1904837,BP,"beta-catenin-TCF complex assembly","The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.",TAS