go_id,ontology,go_term,term_definition,evidence GO:0000812,CC,"Swr1 complex","A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.",IBA GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0006334,BP,"nucleosome assembly","The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.",IDA GO:0006913,BP,"nucleocytoplasmic transport","The directed movement of molecules between the nucleus and the cytoplasm.",IDA|TAS GO:0016023,CC,"cytoplasmic, membrane-bounded vesicle","A membrane-bounded vesicle found in the cytoplasm of the cell.",IEA GO:0016569,BP,"chromatin modification","The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.",IEA GO:0019212,MF,"phosphatase inhibitor activity","Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.",ISS GO:0042393,MF,"histone binding","Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.",IPI GO:0042981,BP,"regulation of apoptotic process","Any process that modulates the occurrence or rate of cell death by apoptotic process.",TAS GO:0043086,BP,"negative regulation of catalytic activity","Any process that stops or reduces the activity of an enzyme.",IEA GO:0043486,BP,"histone exchange","The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.",IBA