go_id,ontology,go_term,term_definition,evidence GO:0003676,MF,"nucleic acid binding","Interacting selectively and non-covalently with any nucleic acid.",IEA GO:0004842,MF,"ubiquitin-protein transferase activity","Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.",IBA GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0007250,BP,"activation of NF-kappaB-inducing kinase activity","The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.",NAS GO:0016874,MF,"ligase activity","Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.",IEA GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA GO:0070534,BP,"protein K63-linked ubiquitination","A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.",ISS