go_id,ontology,go_term,term_definition,evidence
GO:0000774,MF,"adenyl-nucleotide exchange factor activity","Stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.",TAS
GO:0001405,CC,"presequence translocase-associated import motor","Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the presequence translocase complex; hydrolyzes ATP to provide the force to drive import of proteins into the mitochondrial matrix.",IBA
GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA
GO:0005739,CC,mitochondrion,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",IEA
GO:0005759,CC,"mitochondrial matrix","The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.",TAS
GO:0006457,BP,"protein folding","The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.",IEA
GO:0030150,BP,"protein import into mitochondrial matrix","The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.",IBA
GO:0042803,MF,"protein homodimerization activity","Interacting selectively and non-covalently with an identical protein to form a homodimer.",IEA
GO:0050790,BP,"regulation of catalytic activity","Any process that modulates the activity of an enzyme.",IEA
GO:0051082,MF,"unfolded protein binding","Interacting selectively and non-covalently with an unfolded protein.",IDA
GO:0051087,MF,"chaperone binding","Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.",IDA