go_id,ontology,go_term,term_definition,evidence GO:0005789,CC,"endoplasmic reticulum membrane","The lipid bilayer surrounding the endoplasmic reticulum.",IEA GO:0006508,BP,proteolysis,"The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.",IEA GO:0008237,MF,"metallopeptidase activity","Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.",IDA|IMP|TAS GO:0016020,CC,membrane,"A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.",IDA GO:0016021,CC,"integral component of membrane","The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IEA GO:0046872,MF,"metal ion binding","Interacting selectively and non-covalently with any metal ion.",IEA