go_id,ontology,go_term,term_definition,evidence GO:0000086,BP,"G2/M transition of mitotic cell cycle","The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.",TAS GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0007067,BP,"mitotic nuclear division","A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",IEA GO:0007088,BP,"regulation of mitotic nuclear division","Any process that modulates the frequency, rate or extent of mitosis.",TAS GO:0019901,MF,"protein kinase binding","Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.",IEA GO:0032880,BP,"regulation of protein localization","Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.",IEA GO:0051301,BP,"cell division","The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.",IEA GO:0060236,BP,"regulation of mitotic spindle organization","Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.",IEA