go_id,ontology,go_term,term_definition,evidence GO:0001525,BP,angiogenesis,"Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.",IEA GO:0001938,BP,"positive regulation of endothelial cell proliferation","Any process that activates or increases the rate or extent of endothelial cell proliferation.",TAS GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0006457,BP,"protein folding","The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.",IEA GO:0006915,BP,"apoptotic process","A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.",IEA GO:0008479,MF,"queuine tRNA-ribosyltransferase activity","Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.",IBA GO:0008616,BP,"queuosine biosynthetic process","The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.",IBA GO:0016032,BP,"viral process","A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.",IEA GO:0043184,MF,"vascular endothelial growth factor receptor 2 binding","Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2.",ISS GO:0044183,MF,"protein binding involved in protein folding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.",IEA GO:0045766,BP,"positive regulation of angiogenesis","Any process that activates or increases angiogenesis.",IEA GO:0050730,BP,"regulation of peptidyl-tyrosine phosphorylation","Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.",IMP GO:2000059,BP,"negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process","Any process that stops, prevents, or reduces the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process.",IEA