go_id,ontology,go_term,term_definition,evidence
GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA
GO:0005680,CC,"anaphase-promoting complex","A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.",IDA
GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA
GO:0007067,BP,"mitotic nuclear division","A cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.",IEA
GO:0031145,BP,"anaphase-promoting complex-dependent catabolic process","The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.",TAS
GO:0042787,BP,"protein ubiquitination involved in ubiquitin-dependent protein catabolic process","The process in which a ubiquitin group, or multiple groups, are covalently attached to the target protein, thereby initiating the degradation of that protein.",IEA
GO:0043161,BP,"proteasome-mediated ubiquitin-dependent protein catabolic process","The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.",TAS
GO:0051301,BP,"cell division","The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.",IEA
GO:0051436,BP,"negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.",TAS
GO:0051437,BP,"positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition","Any process that activates, maintains or increases the rate of ubiquitin ligase activity that contributes to the regulation of the mitotic cell cycle phase transition.",TAS
GO:0051439,BP,"regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.",TAS
GO:0070979,BP,"protein K11-linked ubiquitination","A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.",IDA