go_id,ontology,go_term,term_definition,evidence
GO:0005123,MF,"death receptor binding","Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).",IEA
GO:0005765,CC,"lysosomal membrane","The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.",TAS
GO:0005794,CC,"Golgi apparatus","A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.",IDA
GO:0010008,CC,"endosome membrane","The lipid bilayer surrounding an endosome.",TAS
GO:0016021,CC,"integral component of membrane","The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.",IEA
GO:0043086,BP,"negative regulation of catalytic activity","Any process that stops or reduces the activity of an enzyme.",IEA
GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA
GO:0090005,BP,"negative regulation of establishment of protein localization to plasma membrane","Any process that decreases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.",IMP
GO:1902042,BP,"negative regulation of extrinsic apoptotic signaling pathway via death domain receptors","Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.",IMP|TAS
GO:1902045,BP,"negative regulation of Fas signaling pathway","Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway.",IMP
GO:2000504,BP,"positive regulation of blood vessel remodeling","Any process that activates or increases the frequency, rate or extent of blood vessel remodeling.",ISS