go_id,ontology,go_term,term_definition,evidence
GO:0001972,MF,"retinoic acid binding","Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.",IDA
GO:0005506,MF,"iron ion binding","Interacting selectively and non-covalently with iron (Fe) ions.",IEA
GO:0005789,CC,"endoplasmic reticulum membrane","The lipid bilayer surrounding the endoplasmic reticulum.",IEA
GO:0006766,BP,"vitamin metabolic process","The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.",TAS
GO:0006805,BP,"xenobiotic metabolic process","The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.",IEA
GO:0008401,MF,"retinoic acid 4-hydroxylase activity","Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.",IDA|TAS
GO:0016709,MF,"oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.",IDA
GO:0019825,MF,"oxygen binding","Interacting selectively and non-covalently with oxygen (O2).",TAS
GO:0020037,MF,"heme binding","Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.",NAS
GO:0031090,CC,"organelle membrane","A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.",IEA
GO:0034653,BP,"retinoic acid catabolic process","The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.",IDA
GO:0042573,BP,"retinoic acid metabolic process","The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.",IDA
GO:0048387,BP,"negative regulation of retinoic acid receptor signaling pathway","Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.",IDA
GO:0055114,BP,"oxidation-reduction process","A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.",IEA