go_id,ontology,go_term,term_definition,evidence GO:0000398,BP,"mRNA splicing, via spliceosome","The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.",IGI GO:0000932,CC,"cytoplasmic mRNA processing body","A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci.",IEA GO:0003723,MF,"RNA binding","Interacting selectively and non-covalently with an RNA molecule or a portion thereof.",IEA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005654,CC,nucleoplasm,"That part of the nuclear content other than the chromosomes or the nucleolus.",IDA GO:0005688,CC,"U6 snRNP","A ribonucleoprotein complex that contains small nuclear RNA U6.",IBA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0017070,MF,"U6 snRNA binding","Interacting selectively and non-covalently with the U6 small nuclear RNA (U6 snRNA).",NAS GO:0017160,MF,"Ral GTPase binding","Interacting selectively and non-covalently with Ral protein, any member of the Ral subfamily of the Ras superfamily of monomeric GTPases.",IPI GO:0043928,BP,"exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail.",TAS GO:0044822,MF,"poly(A) RNA binding","Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.",IDA GO:0046540,CC,"U4/U6 x U5 tri-snRNP complex","A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins.",IBA GO:0071011,CC,"precatalytic spliceosome","A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.",IBA GO:0071013,CC,"catalytic step 2 spliceosome","A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.",IDA GO:1990726,CC,"Lsm1-7-Pat1 complex","A conserved protein complex that plays an important role in coupling deadenylation and decapping in the 5'-to-3' mRNA decay pathway. An example is found in S. cerevisiae.",IBA