go_id,ontology,go_term,term_definition,evidence GO:0001666,BP,"response to hypoxia","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.",IEA GO:0004018,MF,"N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity","Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.",IDA|TAS GO:0005739,CC,mitochondrion,"A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.",IEA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0006164,BP,"purine nucleotide biosynthetic process","The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.",IBA GO:0006167,BP,"AMP biosynthetic process","The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.",IDA|NAS GO:0006189,BP,"de novo' IMP biosynthetic process","The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.",IEA|NAS GO:0007584,BP,"response to nutrient","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.",IEA GO:0009060,BP,"aerobic respiration","The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.",IBA GO:0009168,BP,"purine ribonucleoside monophosphate biosynthetic process","The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.",TAS GO:0014850,BP,"response to muscle activity","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.",IEA GO:0042594,BP,"response to starvation","Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.",IEA GO:0044208,BP,"de novo' AMP biosynthetic process","The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).",IBA|IEA GO:0051262,BP,"protein tetramerization","The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.",IDA GO:0070626,MF,"(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity","Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.",IBA