go_id,ontology,go_term,term_definition,evidence
GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005813,CC,centrosome,"A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.",IDA
GO:0007020,BP,"microtubule nucleation","The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).",IEA
GO:0015630,CC,"microtubule cytoskeleton","The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.",IDA
GO:0031116,BP,"positive regulation of microtubule polymerization","Any process that activates or increases the frequency, rate or extent of microtubule polymerization.",IDA
GO:0031122,BP,"cytoplasmic microtubule organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.",IBA
GO:0035371,CC,"microtubule plus-end","The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.",IDA