go_id,ontology,go_term,term_definition,evidence GO:0000139,CC,"Golgi membrane","The lipid bilayer surrounding any of the compartments of the Golgi apparatus.",IEA GO:0004842,MF,"ubiquitin-protein transferase activity","Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.",IBA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0005783,CC,"endoplasmic reticulum","The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).",IDA GO:0006351,BP,"transcription, DNA-templated","The cellular synthesis of RNA on a template of DNA.",IEA GO:0006355,BP,"regulation of transcription, DNA-templated","Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.",IBA GO:0007030,BP,"Golgi organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.",IMP GO:0007049,BP,"cell cycle","The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.",NAS GO:0016567,BP,"protein ubiquitination","The process in which one or more ubiquitin groups are added to a protein.",IMP GO:0016601,BP,"Rac protein signal transduction","A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.",IDA GO:0017137,MF,"Rab GTPase binding","Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.",IDA GO:0030334,BP,"regulation of cell migration","Any process that modulates the frequency, rate or extent of cell migration.",IBA GO:0032580,CC,"Golgi cisterna membrane","The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.",IEA GO:0042787,BP,"protein ubiquitination involved in ubiquitin-dependent protein catabolic process","The process in which a ubiquitin group, or multiple groups, are covalently attached to the target protein, thereby initiating the degradation of that protein.",IEA GO:0048365,MF,"Rac GTPase binding","Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.",IEA GO:0061025,BP,"membrane fusion","The membrane organization process that joins two lipid bilayers to form a single membrane.",TAS GO:0070936,BP,"protein K48-linked ubiquitination","A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.",IEA