go_id,ontology,go_term,term_definition,evidence GO:0003924,MF,"GTPase activity","Catalysis of the reaction: GTP + H2O = GDP + phosphate.",IEA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005525,MF,"GTP binding","Interacting selectively and non-covalently with GTP, guanosine triphosphate.",IEA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA GO:0007266,BP,"Rho protein signal transduction","A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.",TAS GO:0008360,BP,"regulation of cell shape","Any process that modulates the surface configuration of a cell.",IBA GO:0030036,BP,"actin cytoskeleton organization","A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.",NAS GO:0051056,BP,"regulation of small GTPase mediated signal transduction","Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.",TAS GO:0061299,BP,"retina vasculature morphogenesis in camera-type eye","The process in which the vasculature of the retina is generated and organized.",ISS GO:0070062,CC,"extracellular exosome","A membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.",IDA