go_id,ontology,go_term,term_definition,evidence
GO:0005095,MF,"GTPase inhibitor activity","Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.",TAS
GO:0005198,MF,"structural molecule activity","The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell.",IBA
GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA
GO:0005856,CC,cytoskeleton,"Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.",IBA
GO:0005886,CC,"plasma membrane","The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.",IEA
GO:0006909,BP,phagocytosis,"An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.",IBA
GO:0007165,BP,"signal transduction","The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.",IEA
GO:0008360,BP,"regulation of cell shape","Any process that modulates the surface configuration of a cell.",IBA
GO:0034260,BP,"negative regulation of GTPase activity","Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.",IEA