go_id,ontology,go_term,term_definition,evidence GO:0000932,CC,"cytoplasmic mRNA processing body","A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci.",IEA GO:0003729,MF,"mRNA binding","Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.",IBA GO:0005515,MF,"protein binding","Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).",IPI GO:0005634,CC,nucleus,"A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.",IEA GO:0005737,CC,cytoplasm,"All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.",IDA GO:0005829,CC,cytosol,"The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.",IBA GO:0008565,MF,"protein transporter activity","Enables the directed movement of proteins into, out of or within a cell, or between cells.",IBA|ISS GO:0015031,BP,"protein transport","The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.",IEA GO:0016020,CC,membrane,"A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.",IDA GO:0016605,CC,"PML body","A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.",IEA GO:0016607,CC,"nuclear speck","A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.",IEA GO:0017148,BP,"negative regulation of translation","Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.",IDA GO:0019827,BP,"stem cell population maintenance","The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.",ISS GO:0043231,CC,"intracellular membrane-bounded organelle","Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.",IDA GO:0044822,MF,"poly(A) RNA binding","Interacting non-covalently with a poly(A) RNA, a RNA molecule which has a tail of adenine bases.",IDA GO:0045665,BP,"negative regulation of neuron differentiation","Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.",IEA